成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

  2. 誘導(dǎo)疾病模型產(chǎn)品 Membrane Transporter/Ion Channel
  3. 神經(jīng)系統(tǒng)疾病模型 Potassium Channel
  4. 震顫模型
  5. Penitrem A

Penitrem A  (Synonyms: 青霉震顫素)

目錄號: HY-N6776 純度: 98.57%
COA 產(chǎn)品使用指南

Penitrem A 是由青霉菌產(chǎn)生的吲哚二萜神經(jīng)毒性生物堿，是一種選擇性的 BK 通道拮抗劑，對多種惡性腫瘤具有抗增殖、抗侵襲作用。Penitrem A 能刺激腦皮質(zhì)突觸體增加內(nèi)源性谷氨酸、GABA 和天門冬氨酸的自發(fā)釋放，能誘發(fā)動物產(chǎn)生震顫綜合征。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報，我們不為任何個人用途提供產(chǎn)品和服務(wù)

Penitrem A Chemical Structure

Penitrem A Chemical Structure

CAS No. : 12627-35-9

1.  客戶無需承擔(dān)相應(yīng)的運輸費用。

2.  同一機構(gòu)（單位）同一產(chǎn)品試用裝僅限申領(lǐng)一次，同一機構(gòu)（單位）一年內(nèi)

     可免費申領(lǐng)三個不同產(chǎn)品的試用裝。

3.  試用裝只面向終端客戶。

規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥2240
In-stock
5 mg ￥5600
In-stock
10 mg   詢價  
50 mg   詢價  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2].

IC50 & Target

BK channel[1]
細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
8.4 μM
Compound: 9
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
[PMID: 27462726]
HL-60 IC50
7 μM
Compound: 9
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 27462726]
體內(nèi)研究
(In Vivo)

Penitrem A 可用于動物建模，構(gòu)建震顫綜合征模型。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

634.20

Formula

C37H44ClNO6
CAS 號
性狀

固體

顏色

White to light brown

中文名稱

青霉震顫素
結(jié)構(gòu)分類
初始來源

Penicillium
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥99.0%

參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的產(chǎn)品:

Your information is safe with us. * Required Fields.

   產(chǎn)品名稱：

  

* 需求量：

* 客戶姓名：

 

* Email：

* 電話：

 

* 公司或機構(gòu)名稱：

   留言給我們：

Bulk Inquiry

Inquiry Information

產(chǎn)品名稱：
Penitrem A
目錄號：
HY-N6776
需求量：