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  4. Ceanothic acid

Ceanothic acid  (Synonyms: Emmolic acid)

目錄號: HY-N3558 純度: ≥98.0%
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Ceanothic acid (Emmolic acid) 是樺木酸的同源物。Ceanothic acid 抑制 OVCAR-3,HeLa 和 FS-5 細胞,細胞存活率分別為 68%,65% 和 81%。

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Ceanothic acid Chemical Structure

Ceanothic acid Chemical Structure

CAS No. : 21302-79-4

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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Ceanothic acid (Emmolic acid) is a ring-A homologue of betulinic acid. Ceanothic acid inhibits OVCAR-3, HeLa, and FS-5 cells with the cell survival of 68%, 65%, and 81%, respectively[1].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
C3H 10T1/2 IC50
> 200 μM
Compound: 5
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by fluorometric microculture cytotoxicity assay
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by fluorometric microculture cytotoxicity assay
[PMID: 18842418]
DU-145 IC50
> 200 μM
Compound: 5
Cytotoxicity against human DU145 cells after 24 hrs by fluorometric microculture cytotoxicity assay
Cytotoxicity against human DU145 cells after 24 hrs by fluorometric microculture cytotoxicity assay
[PMID: 18842418]
HaCaT IC50
> 200 μM
Compound: 5
Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay
Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay
[PMID: 18842418]
HepG2 IC50
> 10 μM
Compound: 19
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
[PMID: 27617953]
PANC-1 IC50
195 μM
Compound: 5
Cytotoxicity against human PANC1 after 24 hrs by fluorometric microculture cytotoxicity assay
Cytotoxicity against human PANC1 after 24 hrs by fluorometric microculture cytotoxicity assay
[PMID: 18842418]
分子量

486.68

Formula

C30H46O5

CAS 號
性狀

固體

顏色

White to off-white

中文名稱

美洲茶酸

結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻
  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Ceanothic acid
目錄號:
HY-N3558
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