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  2. Anti-infection
  3. Fungal
  4. Cauloside A

Cauloside A  (Synonyms: Leontoside A)

目錄號: HY-N3557 純度: 99.55%
COA 產(chǎn)品使用指南

Cauloside A (Leontoside A) 是從 Dipsacus asper 根中分離出的皂苷。Cauloside A 具有有效的抗真菌 (antifungal) 活性。

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Cauloside A Chemical Structure

Cauloside A Chemical Structure

CAS No. : 17184-21-3

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1600
In-stock
5 mg ￥4000
In-stock
10 mg ￥6000
In-stock
50 mg   詢價  
100 mg   詢價  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity[1][2].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
29.71 μM
Compound: 10a
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23992864]
A549 IC50
40 μM
Compound: 23
Cell membrane permeabilization in human A549 cells assessed as drug level causing decrease in calcein fluorescence
Cell membrane permeabilization in human A549 cells assessed as drug level causing decrease in calcein fluorescence
[PMID: 19200744]
A549 IC50
58 μM
Compound: 23
Cytotoxicity against human A549 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human A549 cells after 48 hrs by resazurin reduction test
[PMID: 19200744]
DLD-1 IC50
54 μM
Compound: 23
Cell membrane permeabilization in human DLD1 cells assessed as drug level causing decrease in calcein fluorescence
Cell membrane permeabilization in human DLD1 cells assessed as drug level causing decrease in calcein fluorescence
[PMID: 19200744]
DLD-1 IC50
57 μM
Compound: 23
Cytotoxicity against human DLD1 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human DLD1 cells after 48 hrs by resazurin reduction test
[PMID: 19200744]
HeLa IC50
27.67 μM
Compound: 10a
Cytotoxicity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23992864]
HepG2 IC50
19.12 μM
Compound: 10a
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23992864]
HL-60 IC50
14.52 μM
Compound: 10a
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23992864]
RAW264.7 IC50
2.25 μM
Compound: 14
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitirc oxide production preincubated for 1 hr followed by LPS-stimulation and measured after 18 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitirc oxide production preincubated for 1 hr followed by LPS-stimulation and measured after 18 hrs by Griess assay
[PMID: 31301930]
U-87MG ATCC IC50
18.45 μM
Compound: 10a
Cytotoxicity against human U87MG cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human U87MG cells assessed as cell viability after 72 hrs by MTT assay
[PMID: 23992864]
分子量

604.81

Formula

C35H56O8
CAS 號
性狀

固體

顏色

White to off-white

中文名稱

葳巖仙皂苷A； 常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖苷
結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數(shù)據(jù)
細胞實驗： 

DMSO 中的溶解度 : 100 mg/mL (165.34 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 1.6534 mL 8.2671 mL 16.5341 mL
5 mM 0.3307 mL 1.6534 mL 3.3068 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: 99.55%

參考文獻

完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6534 mL 8.2671 mL 16.5341 mL 41.3353 mL
5 mM 0.3307 mL 1.6534 mL 3.3068 mL 8.2671 mL
10 mM 0.1653 mL 0.8267 mL 1.6534 mL 4.1335 mL
15 mM 0.1102 mL 0.5511 mL 1.1023 mL 2.7557 mL
20 mM 0.0827 mL 0.4134 mL 0.8267 mL 2.0668 mL
25 mM 0.0661 mL 0.3307 mL 0.6614 mL 1.6534 mL
30 mM 0.0551 mL 0.2756 mL 0.5511 mL 1.3778 mL
40 mM 0.0413 mL 0.2067 mL 0.4134 mL 1.0334 mL
50 mM 0.0331 mL 0.1653 mL 0.3307 mL 0.8267 mL
60 mM 0.0276 mL 0.1378 mL 0.2756 mL 0.6889 mL
80 mM 0.0207 mL 0.1033 mL 0.2067 mL 0.5167 mL
100 mM 0.0165 mL 0.0827 mL 0.1653 mL 0.4134 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Cauloside A
目錄號：
HY-N3557
需求量：