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  1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Clenbuterol hydrochloride

Clenbuterol hydrochloride  (Synonyms: 鹽酸克侖特羅; NAB-365 hydrochloride)

目錄號(hào): HY-B1614 純度: 99.98%
COA 產(chǎn)品使用指南

Clenbuterol (NAB-365) hydrochloride 是一種選擇性 β2 腎上腺素能激動(dòng)劑,可增強(qiáng)骨骼肌強(qiáng)度和肥大。Clenbuterol hydrochloride 誘導(dǎo)生長(zhǎng)因子 mRNA,激活星形膠質(zhì)細(xì)胞,保護(hù)大鼠腦組織免受缺血損傷。

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Clenbuterol hydrochloride Chemical Structure

Clenbuterol hydrochloride Chemical Structure

CAS No. : 21898-19-1

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Customer Review

Other Forms of Clenbuterol hydrochloride:

查看 Adrenergic Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 實(shí)驗(yàn)參考方法

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage[1][2][3].

體外研究
(In Vitro)

Clenbuterol increases lipolysis in rat primary adipocytes compared with control. Free glycerol release into the culture medium is 158% and 190% of control values in cultures containing 0.1, or 1 μM Clenbuterol, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

體內(nèi)研究
(In Vivo)

Clenbuterol (0.01-0.5 mg/kg; i.p.; male Long-Evans rats) hydrochloride reduces the cortical infarct volume in Long-Evans rats as measured 7 days after permanent occlusion of the middle cerebral artery[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

313.65

Formula

C12H19Cl3N2O

CAS 號(hào)
性狀

固體

顏色

White to off-white

中文名稱

鹽酸克侖特羅; 鹽酸克倫特羅

結(jié)構(gòu)分類
初始來(lái)源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn): 

DMSO 中的溶解度 : 83.33 mg/mL (265.68 mM; 超聲助溶; 吸濕的 DMSO 對(duì)產(chǎn)品的溶解度有顯著影響,請(qǐng)使用新開(kāi)封的 DMSO)

配制儲(chǔ)備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 3.1883 mL 15.9413 mL 31.8827 mL
5 mM 0.6377 mL 3.1883 mL 6.3765 mL
查看完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請(qǐng)分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用,-20°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用。

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物溶解方案計(jì)算器
請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息:

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

由于實(shí)驗(yàn)過(guò)程有損耗,建議您多配一只動(dòng)物的量
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: 99.98%

參考文獻(xiàn)
Cell Assay
[1]

MTS assay is performed to determine the number of viable cells in culture. Cells are treated with 0 (vehicle only), 0.1, or 1 μM Clenbuterol for 6, 12, 24, or 48 h. The absorbance is measured at 490 nm in a plate reader determine the formazan concentration, which is proportional to the number of living cells in culture[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Administration
[2]

Rats:
Rats are randomly divided into two treatment groups. The control group is provided with standard chow and water ad libitum for 3 weeks, while the Clenbuterol group is provided with standard chow and treated for 3 weeks with Clenbuterol administered via the drinking water (30 mg Clenbuterol/L). Body weight and the amount of water consumed are recorded twice each week. After 3 wk, the animals are anesthetized and hindlimb muscles are excised[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

參考文獻(xiàn)

完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請(qǐng)分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用,-20°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1883 mL 15.9413 mL 31.8827 mL 79.7067 mL
5 mM 0.6377 mL 3.1883 mL 6.3765 mL 15.9413 mL
10 mM 0.3188 mL 1.5941 mL 3.1883 mL 7.9707 mL
15 mM 0.2126 mL 1.0628 mL 2.1255 mL 5.3138 mL
20 mM 0.1594 mL 0.7971 mL 1.5941 mL 3.9853 mL
25 mM 0.1275 mL 0.6377 mL 1.2753 mL 3.1883 mL
30 mM 0.1063 mL 0.5314 mL 1.0628 mL 2.6569 mL
40 mM 0.0797 mL 0.3985 mL 0.7971 mL 1.9927 mL
50 mM 0.0638 mL 0.3188 mL 0.6377 mL 1.5941 mL
60 mM 0.0531 mL 0.2657 mL 0.5314 mL 1.3284 mL
80 mM 0.0399 mL 0.1993 mL 0.3985 mL 0.9963 mL
100 mM 0.0319 mL 0.1594 mL 0.3188 mL 0.7971 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Clenbuterol hydrochloride
目錄號(hào):
HY-B1614
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