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  2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Adrenergic Receptor Endogenous Metabolite
  4. Methyldopa hydrochloride

Methyldopa hydrochloride  (Synonyms: 鹽酸甲基多巴; L-(-)-α-Methyldopa hydrochloride; MK-351 hydrochloride)

目錄號(hào): HY-B0225A
產(chǎn)品使用指南

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) 是一種 α-腎上腺素能激動(dòng)劑（對(duì) α2-adrenergic receptors 有選擇性）。Methyldopa hydrochloride 是一種前體，在中樞神經(jīng)系統(tǒng)中被代謝 (α-Methylepinephrine)。

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Methyldopa hydrochloride Chemical Structure

Methyldopa hydrochloride Chemical Structure

CAS No. : 884-39-9

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Methyldopa hydrochloride 的其他形式現(xiàn)貨產(chǎn)品:

Other Forms of Methyldopa hydrochloride:

MCE 顧客使用本產(chǎn)品發(fā)表的 2 篇科研文獻(xiàn)

查看 Adrenergic Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].

IC50 & Target

α adrenergic receptor

 

體內(nèi)研究
(In Vivo)

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 60-day-old male rats[2]
Dosage: 200 mg/kg
Administration: I.p.
Result: Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
Clinical Trial
分子量

247.68

Formula

C10H14ClNO4
CAS 號(hào)
中文名稱(chēng)

鹽酸甲基多巴； 鹽酸卡比多巴EP雜質(zhì)A
結(jié)構(gòu)分類(lèi)
初始來(lái)源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Methyldopa hydrochloride
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