Prednisolone (Synonyms: 潑尼松龍)

目錄號: HY-17463 純度: 99.96%: FAQs
Data Sheet SDS COA 產(chǎn)品使用指南

摩爾計算器

Prednisolone 是一種有效的，口服活性的皮質(zhì)類固醇和糖皮質(zhì)激素。Prednisolone 的抗炎活性約為氫化可的松的四倍，同時減少了鹽和水的保留。Prednisolone 可用于眼部抗炎研究。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報，我們不為任何個人用途提供產(chǎn)品和服務(wù)

Prednisolone Chemical Structure

CAS No. : 50-24-8

1. 客戶無需承擔(dān)相應(yīng)的運輸費用。

2. 同一機構(gòu)（單位）同一產(chǎn)品試用裝僅限申領(lǐng)一次，同一機構(gòu)（單位）一年內(nèi)

可免費申領(lǐng)三個不同產(chǎn)品的試用裝。

3. 試用裝只面向終端客戶。

規(guī)格	價格	是否有貨
10 mM * 1 mL in DMSO	￥500	In-stock
500 mg	￥400	In-stock
1 g	￥500	In-stock
5 g	￥837	In-stock
10 g		詢價
50 g		詢價

or 大包裝詢價

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Customer Review

Other Forms of Prednisolone:

Prednisolone disodium phosphate In-stock
Prednisolone hemisuccinate In-stock
Prednisolone acetate In-stock
Prednisolone (Standard) In-stock
Prednisolone-d₈ 詢價

MCE 顧客使用本產(chǎn)品發(fā)表的 5 篇科研文獻

•Cell Commun Signal. 2019 Aug 14;17(1):94. [Abstract]
•Cell Rep Methods. 2023 Oct 23;3(10):100599. [Abstract]
•Cancers (Basel). 2022 Oct 19;14(20):5127. [Abstract]
•Drug Test Anal. 2020 Aug 27. [Abstract]
•Chem Biodivers. 2020 May;17(5):e2000056. [Abstract]

Prednisolone 相關(guān)產(chǎn)品

•相關(guān)化合物庫:

•同靶點產(chǎn)品:

•同靶點蛋白產(chǎn)品:

生物活性
純度 & 產(chǎn)品資料
參考文獻

生物活性

Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research^[1]^[2].

細胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
A549	EC₅₀	0.002 nM Compound: 2, pred	Agonist activity at human mineralocorticoid receptor expressed in human A549 cells by fluorescence polarization assay Agonist activity at human mineralocorticoid receptor expressed in human A549 cells by fluorescence polarization assay	[PMID: 21899328]
A549	EC₅₀	13.6 nM Compound: 2, pred	Transrepression activity of glucocorticoid receptor in human A549 cells assessed as inhibition of IL1beta-stimulated NFkappaB-dependent E-selectin transcription by luciferase reporter gene assay Transrepression activity of glucocorticoid receptor in human A549 cells assessed as inhibition of IL1beta-stimulated NFkappaB-dependent E-selectin transcription by luciferase reporter gene assay	[PMID: 21073190]
A549	EC₅₀	13.6 nM Compound: pred	Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luciferase reporter gene assay Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luciferase reporter gene assay	[PMID: 19321341]
A549	EC₅₀	14.4 nM Compound: 2, pred	Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-selectin transcription by luciferase reporter gene assay Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-selectin transcription by luciferase reporter gene assay	[PMID: 21899328]
A549	EC₅₀	15.8 nM Compound: 2, pred	Transrepression activity of glucocorticoid receptor in human A549 cells expressing AP-1 assessed as inhibition of PMA-induced AP-1 activity by luciferase reporter gene assay Transrepression activity of glucocorticoid receptor in human A549 cells expressing AP-1 assessed as inhibition of PMA-induced AP-1 activity by luciferase reporter gene assay	[PMID: 21073190]
A549	EC₅₀	16.1 nM Compound: 2, pred	Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 response element by luciferase reporter gene assay Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 response element by luciferase reporter gene assay	[PMID: 21899328]
A549	IC₅₀	5.8 nM Compound: Prednisolone	Antiinflammatory activity in human A549 cells assessed as inhibition of IL1beta-induced IL6 production preincubated for 30 mins followed by IL1beta-stimulation and measured after 20 hrs by AlphaLisa assay Antiinflammatory activity in human A549 cells assessed as inhibition of IL1beta-induced IL6 production preincubated for 30 mins followed by IL1beta-stimulation and measured after 20 hrs by AlphaLisa assay	[PMID: 30384041]
C2C12	EC₅₀	3.4 nM Compound: Prednisolone	Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cells Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cells	[PMID: 15808489]
CV-1	ED₅₀	4 nM Compound: prednisolone	Activity at human glucocorticoid receptor expressed in CV1 cells assessed as repression of TNF and IL-1-beta-induced E-selectin gene expression by luciferase reporter gene assay Activity at human glucocorticoid receptor expressed in CV1 cells assessed as repression of TNF and IL-1-beta-induced E-selectin gene expression by luciferase reporter gene assay	[PMID: 18032610]
HeLa	EC₅₀	16 nM Compound: 1b	Activation of MMTV in HeLa cells measured by luciferase activity Activation of MMTV in HeLa cells measured by luciferase activity	[PMID: 17181172]
HeLa	EC₅₀	21 nM Compound: 2, pred	Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assay Transactivation activity at GR-alpha in human NP1 Hela cells assessed as inhibition of GAL4-DBD after 20 hrs by luciferase reporter gene assay	[PMID: 21899328]
HeLa	EC₅₀	73.9 nM Compound: 2, pred	Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assay Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assay	[PMID: 21899328]
HeLa	EC₅₀	82.7 nM Compound: 2, pred	Transactivation activity of glucocorticoid receptor ligand binding domain expressed in human NP-1 Hela cells co-expressing GAL4 DNA binding domain by luciferase reporter gene assay Transactivation activity of glucocorticoid receptor ligand binding domain expressed in human NP-1 Hela cells co-expressing GAL4 DNA binding domain by luciferase reporter gene assay	[PMID: 21073190]
HepG2	IC₅₀	23 nM Compound: 1	Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced IL-6 production by ELISA Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced IL-6 production by ELISA	[PMID: 21115247]
HepG2	EC₅₀	26 nM Compound: 1	Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with PEPCK assessed as GRE activation by luciferase reporter gene assay Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with PEPCK assessed as GRE activation by luciferase reporter gene assay	[PMID: 21324689]
HepG2	IC₅₀	4.1 nM Compound: 1	Transrepression activity at GR expressed in IL-1beta- and TNFalpha-stimulated HepG2 cells assessed as inhibition of NFKB- or AP-1 mediated E-selectin transcription by luciferase reporter gene assay Transrepression activity at GR expressed in IL-1beta- and TNFalpha-stimulated HepG2 cells assessed as inhibition of NFKB- or AP-1 mediated E-selectin transcription by luciferase reporter gene assay	[PMID: 21349714]
HepG2	IC₅₀	4.1 nM Compound: 1	Transrepression activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of TNFalpha/IL1beta-stimulated NFkappaB-dependent E-selectin repression by luciferase reporter gene assay Transrepression activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of TNFalpha/IL1beta-stimulated NFkappaB-dependent E-selectin repression by luciferase reporter gene assay	[PMID: 21324689]
HepG2	IC₅₀	4.1 nM Compound: 1	Agonist activity at GR expressed in IL-1beta- and TNFalpha-stimulated HepG2 cells assessed as inhibition of NFKB- or AP-1 mediated E-selectin transcription by luciferase reporter gene assay relative to Dexamethasone Agonist activity at GR expressed in IL-1beta- and TNFalpha-stimulated HepG2 cells assessed as inhibition of NFKB- or AP-1 mediated E-selectin transcription by luciferase reporter gene assay relative to Dexamethasone	[PMID: 21316964]
HepG2	IC₅₀	4.1 nM Compound: 1	Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-selectin transcription by luciferase reporter gene assay Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-selectin transcription by luciferase reporter gene assay	[PMID: 21115247]
HepG2	EC₅₀	5.3 nM Compound: 1	Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as GRE activation by luciferase reporter gene assay Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as GRE activation by luciferase reporter gene assay	[PMID: 21324689]
HepG2	EC₅₀	5.3 nM Compound: 1	Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as transactivation activity by luciferase reporter gene assay Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as transactivation activity by luciferase reporter gene assay	[PMID: 21115247]
HFF	EC₅₀	19 nM Compound: 1b	Induction of aromatase activity in HFF cells assessed as production of beta estradiol by aromatase assay Induction of aromatase activity in HFF cells assessed as production of beta estradiol by aromatase assay	[PMID: 17181172]
Huh-7	EC₅₀	57.4 nM Compound: 2, pred	Transactivation activity at glucocorticoid receptor in human 13D3/Huh7 cells assessed as induction of tyrosine aminotransferase activity after 24 hrs Transactivation activity at glucocorticoid receptor in human 13D3/Huh7 cells assessed as induction of tyrosine aminotransferase activity after 24 hrs	[PMID: 21073190]
Huh-7	EC₅₀	64 nM Compound: 2, pred	Transactivation activity at glucocorticoid receptor alpha human 13D3/Huh7 cells assessed as induction of TAT activity after 4 hrs by spectrophotometry Transactivation activity at glucocorticoid receptor alpha human 13D3/Huh7 cells assessed as induction of TAT activity after 4 hrs by spectrophotometry	[PMID: 21899328]
L1210	ED₅₀	100 μM Compound: Prednisolone	Cytotoxicity against mouse L1210 cells assessed as growth inhibition measured at 72 hrs by trypan blue exclusion assay Cytotoxicity against mouse L1210 cells assessed as growth inhibition measured at 72 hrs by trypan blue exclusion assay	[PMID: 118258]
MG-63	EC₅₀	19 nM Compound: 2, pred	Induction of glutamine synthase expression in human MG63 cells after overnight incubation by spectrophotometry Induction of glutamine synthase expression in human MG63 cells after overnight incubation by spectrophotometry	[PMID: 21899328]
NHDF	IC₅₀	23 nM Compound: 1	Transrepression activity at GR expressed in NHDF cells assessed as IL-1beta-mediated IL-6 transcription by ELISA Transrepression activity at GR expressed in NHDF cells assessed as IL-1beta-mediated IL-6 transcription by ELISA	[PMID: 21349714]
NHDF	IC₅₀	23 nM Compound: 1	Transrepression activity at glucocorticoid receptor in human NHDF cells assessed as inhibition of IL-1beta-stimulated AP1 dependent IL-6 repression by ELISA Transrepression activity at glucocorticoid receptor in human NHDF cells assessed as inhibition of IL-1beta-stimulated AP1 dependent IL-6 repression by ELISA	[PMID: 21324689]
NHDF	IC₅₀	23 nM Compound: 1	Agonist activity at human GR expressed in NHDF cells assessed as inhibition of IL-6 production by ELISA relative to Dexamethasone Agonist activity at human GR expressed in NHDF cells assessed as inhibition of IL-6 production by ELISA relative to Dexamethasone	[PMID: 21316964]
OVCAR-3	IC₅₀	1.1 μM Compound: 35	Cytotoxicity against human OVCAR-3 cells incubated for 72 hrs by SRB assay Cytotoxicity against human OVCAR-3 cells incubated for 72 hrs by SRB assay	[PMID: 32283298]
OVCAR-4	IC₅₀	1.1 μM Compound: 35	Cytotoxicity against human OVCAR-4 cells incubated for 72 hrs by SRB assay Cytotoxicity against human OVCAR-4 cells incubated for 72 hrs by SRB assay	[PMID: 32283298]
PBMC	IC₅₀	13 nM Compound: Pred	Antiinflammatory activity in Wistar rat PBMC assessed as inhibition of LPS-induced TNFalpha release preincubated for 45 mins followed by LPS addition after 18 hrs by ELISA Antiinflammatory activity in Wistar rat PBMC assessed as inhibition of LPS-induced TNFalpha release preincubated for 45 mins followed by LPS addition after 18 hrs by ELISA	[PMID: 27810243]
PBMC	IC₅₀	45 nM Compound: Pred	Antiinflammatory activity in human primary PBMC assessed as inhibition of LPS-induced TNFalpha release preincubated for 45 mins followed by LPS addition after 18 hrs by ELISA Antiinflammatory activity in human primary PBMC assessed as inhibition of LPS-induced TNFalpha release preincubated for 45 mins followed by LPS addition after 18 hrs by ELISA	[PMID: 27810243]
RAW264.7	IC₅₀	25.4 μM Compound: Prednisolone	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production after 4 hrs by ELISA Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production after 4 hrs by ELISA	[PMID: 11000020]
T47D	IC₅₀	> 1000 nM Compound: Prednisolone	Displacement of [3H]progesterone from progesterone receptor in human T47D cells after 20 hrs by scintillation counting method Displacement of [3H]progesterone from progesterone receptor in human T47D cells after 20 hrs by scintillation counting method	[PMID: 30384041]
U-937	IC₅₀	0.033 μM Compound: Prednisolone	Antiinflammatory activity in human U937 cells assessed as inhibition of PMA/LPS-stimulated TNFalpha production after 24 hrs by ELISA Antiinflammatory activity in human U937 cells assessed as inhibition of PMA/LPS-stimulated TNFalpha production after 24 hrs by ELISA	[PMID: 32631542]
U-937	IC₅₀	0.44 μM Compound: Prednisolone	Inhibition of LPS-induced IL-1beta expression in human U-937 cells preincubated for 1 hr followed by LPS addition and measured after 24 hrs by ELISA Inhibition of LPS-induced IL-1beta expression in human U-937 cells preincubated for 1 hr followed by LPS addition and measured after 24 hrs by ELISA	[PMID: 31883489]
U-937	IC₅₀	0.64 μM Compound: Prednisolone	Inhibition of LPS-induced TNF-alpha expression in human U-937 cells preincubated for 1 hr followed by LPS addition and measured after 24 hrs by ELISA Inhibition of LPS-induced TNF-alpha expression in human U-937 cells preincubated for 1 hr followed by LPS addition and measured after 24 hrs by ELISA	[PMID: 31883489]
U-937	IC₅₀	8.2 nM Compound: pred	Antiinflammatory activity in PMA-differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha production incubated for 60 mins prior to LPS challenge measured after 24 hrs Antiinflammatory activity in PMA-differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha production incubated for 60 mins prior to LPS challenge measured after 24 hrs	[PMID: 24446728]

體外研究
(In Vitro)

Prednisolone（0.002-10 μg/mL；3 天）可抑制人類白細胞有絲分裂^[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

體內(nèi)研究
(In Vivo)

Prednisolone（5 mg/kg/天；口服；每周 6 天，持續(xù) 72 周）可顯著預(yù)防小鼠因腎病死亡^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	NZB/NZW mice, immune nephritis model^[3]
Dosage:	5 mg/kg/day
Administration:	Oral, 6 days a week for 72 weeks
Result:	Significantly lowered mortality rate and prolonged life significantly.

Clinical Trial

分子量

360.44

Formula

C₂₁H₂₈O₅

CAS 號

50-24-8

性狀

固體

顏色

White to off-white

中文名稱

潑尼松龍；氫化可松EP雜質(zhì)A

結(jié)構(gòu)分類

Steroids

初始來源

內(nèi)源性代謝物

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	1 year
	-20°C	6 months

溶解性數(shù)據(jù)

細胞實驗：

DMSO 中的溶解度 : 62.5 mg/mL (173.40 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

H₂O 中的溶解度 : 0.1 mg/mL (0.28 mM; 超聲助溶)

配制儲備液

濃度溶劑體積質(zhì)量	1 mg	5 mg	10 mg

1 mM	2.7744 mL	13.8719 mL	27.7439 mL
5 mM	0.5549 mL	2.7744 mL	5.5488 mL
10 mM	0.2774 mL	1.3872 mL	2.7744 mL

查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 1 year; -20°C, 6 months。-80°C儲存時，請在1年內(nèi)使用， -20°C儲存時，請在6個月內(nèi)使用。

* 備注：如您選擇水作為儲備液，請稀釋至工作液后，再用 0.22 μm 的濾膜過濾除菌后使用。

摩爾計算器
稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

濃度 _(start)

體積 _(start)

濃度 _(final)

體積 _(final)

動物實驗：

請根據(jù)您的實驗動物和給藥方式選擇適當(dāng)?shù)娜芙夥桨浮?

以下溶解方案都請先按照 In Vitro 方式配制澄清的儲備液，再依次添加助溶劑：
——為保證實驗結(jié)果的可靠性，澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；體內(nèi)實驗的工作液，建議您現(xiàn)用現(xiàn)配，當(dāng)天使用；
以下溶劑前顯示的百分比是指該溶劑在您配制終溶液中的體積占比；如在配制過程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過加熱和/或超聲的方式助溶

方案一

請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (5.77 mM); 澄清溶液

此方案可獲得 ≥ 2.08 mg/mL（飽和度未知）的澄清溶液。
以 1 mL 工作液為例，取 100 μL 20.8 mg/mL 的澄清 DMSO 儲備液加到 400 μL PEG300 中，混合均勻；再向上述體系中加入 50 μL Tween-80，混合均勻；然后再繼續(xù)加入 450 μL 生理鹽水定容至 1 mL。
生理鹽水的配制：將 0.9 g 氯化鈉，溶解于 ddH?O 并定容至 100 mL，可以得到澄清透明的生理鹽水溶液。
方案二

請依序添加每種溶劑： 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (5.77 mM); 澄清溶液

此方案可獲得 ≥ 2.08 mg/mL（飽和度未知）的澄清溶液。
以 1 mL 工作液為例，取 100 μL 20.8 mg/mL 的澄清 DMSO 儲備液加到 900 μL 20% 的 SBE-β-CD 生理鹽水水溶液中，混合均勻。
2 g SBE-β-CD（磺丁基醚 β-環(huán)糊精）粉末定容于 10 mL 的生理鹽水中，完全溶解至澄清透明。
方案三

請依序添加每種溶劑： 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (5.77 mM); 澄清溶液

此方案可獲得 ≥ 2.08 mg/mL（飽和度未知）的澄清溶液，此方案實驗周期在半個月以上的動物實驗酌情使用。
以 1 mL 工作液為例，取 100 μL 20.8 mg/mL 的澄清 DMSO 儲備液加到 900 μL玉米油中，混合均勻。

動物溶解方案計算器

請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

每只動物的給藥體積

μL

動物數(shù)量

只

由于實驗過程有損耗，建議您多配一只動物的量

請輸入您的動物體內(nèi)配方組成：

DMSO +

Tween-80 +

Saline

如果您的動物是免疫缺陷鼠或者體弱鼠，建議 DMSO 中的在最后工作液體系中的占比盡量不超過 2%。

方案所需 助溶劑 包括：DMSO，，均可在 MCE 網(wǎng)站選購。，Tween 80，均可在 MCE 網(wǎng)站選購。

計算結(jié)果

工作液所需濃度 : mg/mL

儲備液配制方法 : mg 藥物溶于 μL DMSO（母液濃度為 mg/mL）。

您所需的儲備液濃度超過該產(chǎn)品的實測溶解度，以下方案僅供參考，如有需要，請與 MCE 中國技術(shù)支持聯(lián)系。

動物實驗體內(nèi)工作液的配制方法 : 取 μL DMSO 儲備液，加入 μL 。 μL ，混合均勻至澄清，再加 μL Tween 80，混合均勻至澄清，再加 μL 生理鹽水。

連續(xù)給藥周期超過半月以上，請謹慎選擇該方案。

請確保第一步儲備液溶解至澄清狀態(tài)，從左到右依次添加助溶劑。您可采用超聲加熱（超聲清洗儀，建議頻次 20-40 kHz），渦旋吹打等方式輔助溶解。

純度 & 產(chǎn)品資料

純度: 99.96%

選擇批次：

Data Sheet (639 KB) SDS (604 KB)

COA (290 KB) LCMS (268 KB)

產(chǎn)品使用指南 (1538 KB)

參考文獻

[1]. Prednisolone. J Am Pharm Assoc. 1976;16(3):143-146. [Content Brief]

[2]. Musson DG, et al. Assay methodology for prednisolone, prednisolone acetate and prednisolone sodium phosphate in rabbit aqueous humor and ocular physiological solutions. J Chromatogr. 1991;565(1-2):89-102. [Content Brief]

[3]. Hahn B H, et al. Comparison of therapeutic and immunosuppressive effects of azathioprine, prednisolone and combined therapy in nzp/nzw mice. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 1973, 16(2): 163-170.

[4]. NOWELL PC. Inhibition of human leukocyte mitosis by prednisolone in vitro. Cancer Res. 1961 Dec;21:1518-21. [Content Brief]

Prednisolone 相關(guān)分類

完整儲備液配制表

可選溶劑	濃度溶劑體積質(zhì)量	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7744 mL	13.8719 mL	27.7439 mL	69.3597 mL
	5 mM	0.5549 mL	2.7744 mL	5.5488 mL	13.8719 mL
	10 mM	0.2774 mL	1.3872 mL	2.7744 mL	6.9360 mL
	15 mM	0.1850 mL	0.9248 mL	1.8496 mL	4.6240 mL
	20 mM	0.1387 mL	0.6936 mL	1.3872 mL	3.4680 mL
	25 mM	0.1110 mL	0.5549 mL	1.1098 mL	2.7744 mL
	30 mM	0.0925 mL	0.4624 mL	0.9248 mL	2.3120 mL
	40 mM	0.0694 mL	0.3468 mL	0.6936 mL	1.7340 mL
	50 mM	0.0555 mL	0.2774 mL	0.5549 mL	1.3872 mL
	60 mM	0.0462 mL	0.2312 mL	0.4624 mL	1.1560 mL
	80 mM	0.0347 mL	0.1734 mL	0.3468 mL	0.8670 mL
	100 mM	0.0277 mL	0.1387 mL	0.2774 mL	0.6936 mL

* 備注：如您選擇水作為儲備液，請稀釋至工作液后，再用 0.22 μm 的濾膜過濾除菌后使用。

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Prednisolone50-24-8潑尼松龍氫化可松EP雜質(zhì)AGlucocorticoid ReceptorEndogenous Metabolitecorticosteroidglucocorticoidanti-inflammatoryorally activeInhibitorinhibitorinhibit

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Prednisolone (Synonyms: 潑尼松龍)

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摩爾計算器

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