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  1. Cytoskeleton
  2. Integrin
  3. c(phg-isoDGR-(NMe)k)

c(phg-isoDGR-(NMe)k) 是有效選擇性的 α5β1 整合素 配體,IC50 為 2.9 nM。

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c(phg-isoDGR-(NMe)k) Chemical Structure

c(phg-isoDGR-(NMe)k) Chemical Structure

CAS No. : 1844830-65-4

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c(phg-isoDGR-(NMe)k) 的其他形式現(xiàn)貨產(chǎn)品:

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Other Forms of c(phg-isoDGR-(NMe)k):

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM[1].

IC50 & Target

IC50: 2.9 nM (α5β1)[1]

體內(nèi)研究
(In Vivo)

c(phg-isoDGR-(NMe)k) is trimerized with the chelator TRAP and used as a positron-emission tomography tracer for monitoring α5β1 integrin expression in a M21 mouse xenograft[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

603.67

Formula

C27H41N9O7

CAS 號(hào)
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

純度 & 產(chǎn)品資料
參考文獻(xiàn)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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c(phg-isoDGR-(NMe)k)
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