成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

  2. Immunology/Inflammation GPCR/G Protein
  3. COX Prostaglandin Receptor
  4. Ufenamate

Ufenamate  (Synonyms: 氟芬那酸丁酯; Flufenamic acid butyl ester; Butyl flufenamate)

目錄號: HY-100009 純度: 99.89%
COA 產(chǎn)品使用指南 技術(shù)支持

Ufenamate (Flufenamic acid butyl ester) 是一種基于鄰氨基苯甲酸的抗炎試劑，可用于皮膚疾病的研究，例如急慢性濕疹，接觸性皮炎，尿布性皮炎，粟疹和特應(yīng)性皮炎。Ufenamate 具有一定的光保護作用，在光老化模型中減輕皮膚紅斑腫脹程度，下調(diào) COX-2 表達水平，并且可以通過分泌 BMP2 促進小鼠顱骨缺損愈合。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報，我們不為任何個人用途提供產(chǎn)品和服務(wù)

Ufenamate Chemical Structure

Ufenamate Chemical Structure

CAS No. : 67330-25-0

1.  客戶無需承擔(dān)相應(yīng)的運輸費用。

2.  同一機構(gòu)（單位）同一產(chǎn)品試用裝僅限申領(lǐng)一次，同一機構(gòu)（單位）一年內(nèi)

     可免費申領(lǐng)三個不同產(chǎn)品的試用裝。

3.  試用裝只面向終端客戶。

規(guī)格 價格 是否有貨 數(shù)量
10 mM * 1 mL in DMSO ￥500
In-stock
5 mg ￥450
In-stock
10 mg ￥500
In-stock
50 mg ￥650
In-stock
100 mg ￥790
In-stock
200 mg   詢價  
500 mg   詢價  

* Please select Quantity before adding items.

查看 COX 亞型特異性產(chǎn)品:

查看 Prostaglandin Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug that can be used in the study of skin diseases such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliary rashes and atopic dermatitis. Ufenamate has a certain photoprotective effect, reduces the degree of skin erythema and swelling in the photoaging model, downregulates the expression level of COX-2 and can promote the healing of mouse skull defects by secreting BMP2[1][2][3][4].

IC50 & Target

COX-2

 

體內(nèi)研究
(In Vivo)

Ufenamat (2 μL/cm2，軟膏涂抹，單次劑量) 在大鼠中不適合干性皮膚[2]。
Ufenamate (軟膏涂抹，單次劑量) 具有一定的光保護作用, 在小鼠光老化模型中減輕皮膚紅斑腫脹程度，下調(diào) COX-2 表達水平[3]。
Ufenamat (軟膏涂抹，6 和 8 周) 促進小鼠顱骨損傷愈合[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: UV-induced acute sunburn model, photoaging model and skin squamous cell carcinoma model in SKH-1 hairless mice[3]
Dosage: Ointment application
Administration: Ointment application; single dose; 30 min
Result: Inhibited acute swelling and redness caused by UV irradiation and reduced COX-2 expression.
At 12 weeks of irradiation, skin aging was alleviated, the collagen density of the dermis was higher, the expression of Bcl-2 was weakened, and the expression of Bax and Caspase 3 was enhanced.
At 28 weeks of irradiation, the appearance of tumors was delayed.
Animal Model: Intact and damaged skin of rats[2]
Dosage: 2μL/cm2
Administration: Ointment application; single dose
Result: Applied on the damaged skin, contained in the epidermis was approximately 50% and 25% of that in the intact skin after LP and water, respectively, with the content being 5 times and 10 times higher than in the intact skin.
Permeated UF five times more than LP in the intact skin. Reduced significantly the permeation of UF by both LP and water due to the defatting effect of SC.
Animal Model: Skull defect mice[4]
Dosage: Ointment application
Administration: Ointment application; 6 weeks and 8 weeks
Result: Promoted the formation of new bone in the defect area, and the effect was stronger after 8 weeks than at 6 weeks, improving the BV/TV and BMD in the defect area.
分子量

337.34

Formula

C18H18F3NO2
CAS 號
性狀

液體（密度：1.2230 g/cm3）

顏色

Colorless to light yellow

中文名稱

氟滅酸丁酯；烏芬那酯；氟芬那酸丁酯
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性數(shù)據(jù)
細胞實驗： 

DMSO 中的溶解度 : ≥ 44 mg/mL (130.43 mM; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 2.9644 mL 14.8218 mL 29.6437 mL
5 mM 0.5929 mL 2.9644 mL 5.9287 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料
參考文獻

完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9644 mL 14.8218 mL 29.6437 mL 74.1092 mL
5 mM 0.5929 mL 2.9644 mL 5.9287 mL 14.8218 mL
10 mM 0.2964 mL 1.4822 mL 2.9644 mL 7.4109 mL
15 mM 0.1976 mL 0.9881 mL 1.9762 mL 4.9406 mL
20 mM 0.1482 mL 0.7411 mL 1.4822 mL 3.7055 mL
25 mM 0.1186 mL 0.5929 mL 1.1857 mL 2.9644 mL
30 mM 0.0988 mL 0.4941 mL 0.9881 mL 2.4703 mL
40 mM 0.0741 mL 0.3705 mL 0.7411 mL 1.8527 mL
50 mM 0.0593 mL 0.2964 mL 0.5929 mL 1.4822 mL
60 mM 0.0494 mL 0.2470 mL 0.4941 mL 1.2352 mL
80 mM 0.0371 mL 0.1853 mL 0.3705 mL 0.9264 mL
100 mM 0.0296 mL 0.1482 mL 0.2964 mL 0.7411 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的產(chǎn)品:

Your information is safe with us. * Required Fields.

   產(chǎn)品名稱：

  

* 需求量：

* 客戶姓名：

 

* Email：

* 電話：

 

* 公司或機構(gòu)名稱：

   留言給我們：

Bulk Inquiry

Inquiry Information

產(chǎn)品名稱：
Ufenamate
目錄號：
HY-100009
需求量：