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Ropivacaine HCL

  Cat. No.:  DCAPI1439   Featured
Chemical Structure
132112-35-7
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More than 5000 active chemicals with high quality for research!
Field of application
Ropivacaine Hydrochloride Monohydrate is used as a local anesthetic.
Cas No.: 132112-35-7
Chemical Name: (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrate;hydrochloride
Synonyms: Ropivacaine Hydrochloride Monohydrate; Naropin; Ropivacaine hydrochloride hydrate; Naropin hydrochloride monohydrate; ropivacaine monohydrochloride, (S)-isomer; AL 381; AL-381; LEA 103; LEA-103;
SMILES: O=C(NC1=C(C)C=CC=C1C)[C@H]2N(CCC)CCCC2.O.Cl
Formula: C17H29ClN2O2
M.Wt: 328.88
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.Ropivacaine is a new long-acting local anesthetic, with vasoconstrictive properties. Ropivacaine given epidurally provided adequate sensory anesthesia and motor block for transurethral surgery. Addition of epinephrine did not provide any significant prolongation of the sensory or motor block, nor any influence upon the sympathetic block [1]. Ropivacaine was metabolized to 2',6'-pipecoloxylidide (PPX), 3'-hydroxyropivacaine (3'-OH Rop), and 4'-hydroxyropivacaine (4'-OH Rop) by hepatic microsomes from human and rat. Ropivacaine N-dealkylation and 3'-hydroxylation activities correlated well with the level of CYP3A4 and 1A2 in human hepatic microsomes, respectively [2].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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