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  2. Metabolic Enzyme/Protease Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Endogenous Metabolite Histamine Receptor
  4. Olopatadine

Olopatadine 是一種具有口服活性和選擇性的組胺 1 (H1) 受體拮抗劑，也是肥大細(xì)胞穩(wěn)定劑。Olopatadine 可以防止人結(jié)膜肥大細(xì)胞釋放免疫刺激的促炎介質(zhì)。Olopatadine 可用于過敏性結(jié)膜炎的研究。

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Olopatadine Chemical Structure

Olopatadine Chemical Structure

CAS No. : 113806-05-6

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規(guī)格 價(jià)格 是否有貨
5 mg ￥1440
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Olopatadine 的其他形式現(xiàn)貨產(chǎn)品:

Customer Review

Other Forms of Olopatadine:

查看 Histamine Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[1][2].

IC50 & Target[1]

H1 Receptor

 

體外研究
(In Vitro)

Olopatadine inhibits anti-IgE antibody-mediated release of TNF-α from human conjunctival mast cells, and significantly decreases the mast cell supernatant-mediated upregulation of ICAM (intercellular adhesion molecule)-1 on human conjunctival epithelial cells in vitro[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

337.41

Formula

C21H23NO3
CAS 號
結(jié)構(gòu)分類
初始來源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Olopatadine
目錄號：
HY-W062109
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