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    2. 
                        
                            Antibody-drug Conjugate/ADC Related
                        
                            PROTAC
                        
                        
                    
      3. 
                
                    
                    
    3. 
                        
                            ADC Linker
                        
                            PROTAC Linkers
                        
                        
                    
      4. 
                
                
    4. 
                    
                    Fmoc-NH-PEG1-CH2COOH
                    
                
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                            Fmoc-NH-PEG1-CH2COOH 是一種可降解的 ADC linker，用于抗體活性分子偶聯(lián)物 (ADC) 合成。Fmoc-NH-PEG1-CH2COOH 也是一種基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。
                        
                        
                        
                        
	                
    
	            
    

                
                
    
                    
    
                        
                        
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	                            Fmoc-NH-PEG1-CH2COOH Chemical Structure
                            
                            
                            
                        
    
                            
    Fmoc-NH-PEG1-CH2COOH Chemical Structure
    
                        
                        
                        

                            
    CAS No. :
                                
                                    260367-12-2
                                
                            
    
                        
	                
    
                    
                    
	                
    
                        
    
                            
    
                            
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                                        500 mg
                                    
                                    
                                        
                                            
                                                ￥100
                                            
                                            
                                            
    
                                            
                                        
                                        
                                        		
                                    
                                        
                                            
                                                
                                                
                                                
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                                        1 g
                                    
                                    
                                        
                                            
                                                ￥160
                                            
                                            
                                            
    
                                            
                                        
                                        
                                        		
                                    
                                        
                                            
                                                
                                                
                                                
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                                        5 g
                                    
                                    
                                        
                                            
                                                ￥640
                                            
                                            
                                            
    
                                            
                                        
                                        
                                        		
                                    
                                        
                                            
                                                
                                                
                                                
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                                        10 g
                                    
                                    
                                        
                                            
                                                ￥1184
                                            
                                            
                                            
    
                                            
                                        
                                        
                                        		
                                    
                                        
                                            
                                                
                                                
                                                
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                                        25 g
                                    
                                    
                                        
                                            
                                                ￥2801
                                            
                                            
                                            
    
                                            
                                        
                                        
                                        		
                                    
                                        
                                            
                                                
                                                
                                                
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                                                50 g
                                                 
                                                
                                                    詢價(jià)
                                                    
                                                
                                                 
                                            
    
                                        
                                    
                                    
                                
                            
    
                        
                        
    
                        
    
                        


	                    
    
	                        
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    • 生物活性
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    • 純度 & 產(chǎn)品資料
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	                        生物活性
	                        
	                            
    
	                            	
    
                                    
                                    
	                                
										Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
									
									
                                    
									
    
	                            
    
	                            		
	                    
    
	                    
                        
                        
                        
                            
    
                                IC50 & Target[1]
                                
                                    
                                    
    
                                        
                                            
    
                                                
    Cleavable Linker
    
                                                
    
                                                    
                                                     
                                                
    
                                                		
                                        
                                            
                                                
    Alkyl/ether
    
                                                
    
                                                    
                                                     
                                                
    
                                                		
                                        
                                            
                                                
    PEGs
    
                                                
    
                                                    
                                                     
                                                
    
                                                		
                                        
                                    
    
                                        
                                    		
                            
    
                        
                        
                        
                        
                            
    
                                體外研究
    (In Vitro)    		
                                
                                    
    
                                        
                                        
                                            
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
    
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
    
                                            
    MCE has not independently confirmed the accuracy of these methods. They are for reference only.
    
                                        
                                        
                                            
                                            
    
                                                
                                                
                                            
    
                                            
                                        

                                        
                                    
    
                                    		
                            
    
                        
                        
                        
	                    
                        
                        
                        
                            
    
                                分子量
                                
                                    
    
                                        
    
                                            
                                                341.36
                                            
                                            
                                        
    
                                    
    
                                    		
                            
    
                        
                        
                        
                        
                        
                        
                        
                        
                        
                            
    
                                Formula
                                
                                    
    C19H19NO5
    
                                    		
                            
    
                        
                        
                            
    
                                CAS 號(hào)
                                
                                    
                                
                            
    
                        
                        
                        
                            
    
                                性狀
                                
                                    
    
                                        
    
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                                            White to off-white
                                        
    
                                    
    
                                    		
                            
    
                        
                        
                        
                        
                        
                        
                        
                            
                        
                        
                        
                        
                        
                            
    
                                運(yùn)輸條件
                                
    
                                    
                                    
                                        
    Room temperature in continental US; may vary elsewhere.
    
                                    
                                        
                                
    		
                            
    
                        
                        
                        
                        
    
                            儲(chǔ)存方式
                            
                                
    
                                    
                                    
                                        
    
                                            
                                                
    
                                                    Powder
                                                    -20°C
                                                    3 years
                                                
    
                                            
                                                
    
                                                    
                                                    4°C
                                                    2 years
                                                
    
                                            
                                                
    
                                                    In solvent
                                                    -80°C
                                                    6 months
                                                
    
                                            
                                                
    
                                                    
                                                    -20°C
                                                    1 month
                                                
    
                                            
                                        
    
                                    
                                    
                                
    
                                		
                        
    
                        
                        
                        
                            
                            
                            
                        
                        
                        
                        
                        
                        
                        
                        
                            
    
                                純度 & 產(chǎn)品資料
                                
                                
    
                                    

                                        
    
                                            
                                                
    
                                                    
                                                        
                                                            純度: 99.91%
                                                        
                                                    
                                                    
                                                    
                                                
    
                                            

                                            
                                        
    
                                    

                                    
                                
    
                                    		
                            
    
                        

                        
                        

                        
                        
						
	                    
    
	                        參考文獻(xiàn)
	                        
	                            
	                        
	                    
    
	                    
                        
	                
    
	            
    
                
                
                
                
                
    
                
    
	            
	            
	            
                
                
                
                
                
                    
                

                
                
                    
    
                        
      
                            
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    The molarity calculator equation
    

    
    
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    

    

    
    
    
        
    
            
            
    
                質(zhì)量
                 
                濃度
                 
                體積
                 
                分子量 *
            
    
            
    
                
                    
                    
                
                =
                
                    
                    
                
                ×
                
                    
                    
                
                ×
                
                    
                
            
    
                
        
    
    
    
    
      
        
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    The dilution calculator equation
    

    
    
    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    
    
    This equation is commonly abbreviated as: C1V1 = C2V2
    

    

    
    
    
        
    
            
            
    
                濃度 (start)
                ×
                體積 (start)
                =
                濃度 (final)
                ×
                體積 (final)
            
    
            
    
                
                    
                    
                
                ×
                
                    
                    
                
                =
                
                    
                    
                
                ×
                
                    
                    
                
            
    
            
    
                C1
                 
                V1
                 
                C2
                 
                V2
            
    
                
        
    
    
    
    
      
        
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                        Help & FAQs
                    
    
                    
      
                        
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                            Do most proteins show cross-species activity?
                            
      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
      
                        
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    Bulk Inquiry
    
	    
    
	        
    
	        
	        
    Inquiry Information
    
	        
    
	            
    產(chǎn)品名稱：
    
	            
    Fmoc-NH-PEG1-CH2COOH
    
	            
    目錄號(hào)：
    
	            
    HY-W055861
    
	            
    需求量：