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  2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. BnO-PEG6-OH

BnO-PEG6-OH 是一種不可降解 (non-cleavable) 的含 6 個(gè)單元 PEG 的 ADC linker，可用于合成抗體偶聯(lián)活性分子 (ADC)。BnO-PEG6-OH 也是一種 PROTAC linker，屬于 PEG 類， 可用于合成 PROTAC 分子。

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BnO-PEG6-OH Chemical Structure

BnO-PEG6-OH Chemical Structure

CAS No. : 24342-68-5

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規(guī)格 價(jià)格 是否有貨 數(shù)量
250 mg ￥100
In-stock
500 mg ￥170
In-stock
1 g ￥286
In-stock
5 g ￥1000
In-stock
10 g ￥1650
In-stock
25 g ￥3797
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50 g   詢價(jià)  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BnO-PEG6-OH is also a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].

IC50 & Target

Non-cleavable Linker

 

PEGs

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

372.45

Formula

C19H32O7
CAS 號(hào)
性狀

液體（密度：1.097 g/cm3）

顏色

Colorless to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: 99.88%

參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
BnO-PEG6-OH
目錄號(hào)：
HY-W042654
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