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  2. GPCR/G Protein
  3. Motilin Receptor
  4. Motilin (26-47), human, porcine

Motilin (26-47), human, porcine  (Synonyms: 胃動素 (人類，豬))

目錄號: HY-P1037 純度: 95.56%
COA 產(chǎn)品使用指南

Motilin (26-47), human, porcine 是一種內(nèi)源性的 motilin 受體激動劑，在中國倉鼠卵巢細胞中，Ki 值和 EC50 值分別為 2.3 nM 和 0.3 nM。

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Custom Peptide Synthesis

Motilin (26-47), human, porcine Chemical Structure

Motilin (26-47), human, porcine Chemical Structure

CAS No. : 52906-92-0

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規(guī)格 價格 是否有貨 數(shù)量
500 μg ￥900
In-stock
1 mg ￥1500
In-stock
5 mg ￥4500
In-stock
10 mg 現(xiàn)貨 詢價
50 mg   詢價  
100 mg   詢價  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Motilin (26-47), human, porcine is an endogenous motilin receptor ligand with Ki and EC50 of 2.3 nM and 0.3 nM in a Chinese hamster ovary cell line.

IC50 & Target

EC50: 0.3 nM (motilin receptor, Chinese hamster ovary cell)[1]
Ki: 2.3 nM (motilin receptor, Chinese hamster ovary cell)[1]
體外研究
(In Vitro)

[Bpa1,Ile13]motilin is a full agonist at the motilin receptor that increases intracellular calcium in a concentration-dependent manner (EC50 = 1.5 ± 0.4 nM)[1]. Motilin binds with high affinity (IC50 0.7± 0.2 nM) to receptors on smooth muscle cells. Motilin selectively activates G(q) and G(13), stimulates G alpha(q)-dependent phosphoinositide (PI) hydrolysis and 1,4,5-trisphosphate (IP(3))-dependent Ca2+ release, and increases cytosolic free Ca2+. Motilin induces a biphasic, concentration-dependent contraction (EC50 = 1.0 +/- 0.2 nM), consisting of an initial peak followed by a sustained contraction[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2699.07

Formula

C120H188N34O35S
CAS 號
性狀

固體

顏色

White to off-white

Sequence

Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln
Sequence Shortening

FVPIFTYGELQRMQEKERNKGQ
中文名稱

胃動素 (人類，豬)
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度 & 產(chǎn)品資料
參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Motilin (26-47), human, porcine
目錄號：
HY-P1037
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