8-Hydroxyquinoline (Synonyms: 8-羥基喹啉; 8-Quinolinol)

目錄號(hào): HY-B1005 純度: 99.96%: FAQs
Data Sheet SDS COA 產(chǎn)品使用指南

摩爾計(jì)算器

8-Hydroxyquinoline (8-Quinolinol) 是一種親脂性金屬螯合劑，可用作殺菌劑。8-Hydroxyquinoline 對(duì)臨床分離淋球菌株的最低抑菌范圍為 27.56 -55.11 μM (4-8μg/mL)。8-Hydroxyquinoline 可以與銅形成復(fù)合物，結(jié)合并將銅轉(zhuǎn)運(yùn)到細(xì)胞內(nèi)。8-Hydroxyquinoline 能夠增加小鼠微核多色紅細(xì)胞的數(shù)量，也能使小鼠毛發(fā)脫色。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)

8-Hydroxyquinoline Chemical Structure

CAS No. : 148-24-3

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規(guī)格	價(jià)格	是否有貨
10 mM * 1 mL in DMSO	￥165	In-stock
100 mg	￥150	In-stock
500 mg	￥240	In-stock
1 g	￥288	In-stock
5 g	￥360	In-stock
10 g		詢價(jià)
50 g		詢價(jià)

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Customer Review

Other Forms of 8-Hydroxyquinoline:

8-Hydroxyquinoline hemisulfate In-stock
8-Hydroxyquinoline (Standard) 詢價(jià)

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生物活性
純度 & 產(chǎn)品資料
參考文獻(xiàn)

生物活性

8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice^[1]^[2]^[3]^[4]^[5].

細(xì)胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
A549	IC₅₀	31.25 μM Compound: 8HQ	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
A549	IC₅₀	32.63 μM Compound: 8HQ	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
A549	IC₅₀	6.58 μM Compound: 8HQ	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
FM3A	IC₅₀	2.1 μM Compound: 34	Inhibit growth of FM3A cells by 50% Inhibit growth of FM3A cells by 50%	[PMID: 1732542]
HCT-116	IC₅₀	21.09 μM Compound: 8HQ	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
HCT-116	IC₅₀	26.3 μM Compound: 8HQ	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
HCT-116	IC₅₀	6 μM Compound: 4	Antiproliferative activity against human HCT116 cells after 72 hrs by Cell Titer-Glo assay Antiproliferative activity against human HCT116 cells after 72 hrs by Cell Titer-Glo assay	[PMID: 28191850]
HCT-116	IC₅₀	7.25 μM Compound: 8HQ	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
HeLa	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
HeLa	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
HeLa	IC₅₀	13.5 μM Compound: HQ	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin assay	[PMID: 27191619]
HeLa	IC₅₀	35.65 μM Compound: 8HQ	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
HepG2	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
HepG2	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
HepG2	IC₅₀	32.1 μM Compound: 8HQ	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
KB	IC₅₀	< 2.1 μM Compound: 34	Inhibit growth of KB cells by 50% Inhibit growth of KB cells by 50%	[PMID: 1732542]
MCF7	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
MCF7	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
MCF7	IC₅₀	21.06 μM Compound: 8HQ	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
MES-SA	IC₅₀	5.04 μM Compound: 12	Cytotoxicity against human MES-SA cells assessed as cell growth inhibition incubated for 72 hrs by PrestoBlue reagent based cell viability assay Cytotoxicity against human MES-SA cells assessed as cell growth inhibition incubated for 72 hrs by PrestoBlue reagent based cell viability assay	[PMID: 35613553]
MES-SA/Dx5	IC₅₀	3.04 μM Compound: 12	Cytotoxicity against multidrug resistance human MES-SA/Dx5 cells assessed as cell growth inhibition incubated for 72 hrs by PrestoBlue reagent based cell viability assay Cytotoxicity against multidrug resistance human MES-SA/Dx5 cells assessed as cell growth inhibition incubated for 72 hrs by PrestoBlue reagent based cell viability assay	[PMID: 35613553]
PANC-1	IC₅₀	24.52 μM Compound: 8HQ	Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
PANC-1	IC₅₀	30.44 μM Compound: 8HQ	Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
PANC-1	IC₅₀	7.43 μM Compound: 8HQ	Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
PC-3	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
PC-3	IC₅₀	14.36 μM Compound: 8HQ	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
PC-3	IC₅₀	32.01 μM Compound: 8HQ	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]
Sf9	IC₅₀	1.27 μM Compound: 21	Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using methionylprolyl-p-nitroanilide as substrate preincubated for 20 mins followed by substrate addition measur Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using methionylprolyl-p-nitroanilide as substrate preincubated for 20 mins followed by substrate addition measur	[PMID: 28089350]
SW1990	IC₅₀	> 50 μM Compound: 8HQ	Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 48 hrs in presence of FeCl3 by MTT assay	[PMID: 33453603]
SW1990	IC₅₀	10.23 μM Compound: 8HQ	Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 48 hrs in presence of CuCl2 by MTT assay	[PMID: 33453603]
SW1990	IC₅₀	32.1 μM Compound: 8HQ	Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 33453603]

體外研究
(In Vitro)

8-Hydroxyquinoline (8HQ) (Compd 1) 在 MRC-5 細(xì)胞中顯示細(xì)胞毒性，IC₅₀ 為 6.27 μM^[1]。
8-Hydroxyquinoline (8-OHQ) (Compd 1) (與 CuCl₂ 混合，10.0 μM，1 小時(shí)) 與銅結(jié)合并形成復(fù)合物，可促進(jìn)銅向人乳腺癌 DCIS 細(xì)胞的轉(zhuǎn)運(yùn)^[2]。
8-Hydroxyquinoline (與 CuCl₂ 混合，,0-20.0 μM，1 或 8 小時(shí)) 與銅結(jié)合并形成復(fù)合物，在 DCIS 細(xì)胞中以時(shí)間和劑量依賴性方式誘導(dǎo)細(xì)胞死亡^[2]。
8-Hydroxyquinoline (與 CuCl₂ 混合，1-5 μM，2-12 小時(shí)) 抑制蛋白酶體糜蛋白酶樣活性^[2]。
8-Hydroxyquinoline (0-100 μM，30 分鐘) 通過(guò)阻斷 Raw 264.7 細(xì)胞中的 C/EBPb DNA 結(jié)合活性和 NF-κB 活化來(lái)抑制 NO 產(chǎn)生和 iNOS 表達(dá)，從而抑制炎癥^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:	DCIS cells
Concentration:	1,2.5,5,10,20 μM
Incubation Time:	1 or 8 hour
Result:	Binding to copper and form complexes make the cells rounded up and detached, induces cell death with in a concentration- and time-dependent manner. 8-OHQ- and CQ-Cu, but not mixture of their analogues and Cu, could induce cancer cell death in a concentration- and time-dependent manner.

Western Blot Analysis^[2]

Cell Line:	DCIS cells
Concentration:	1,2.5,5 μM
Incubation Time:	0,2,4,8,12 hours
Result:	Mixture of CuCl₂ inhibited the CT-like activity in a concentration- and time-dependent manner. Mixture of CuCl₂ decreased proteasomal activity and increased ubquititinated proteins and Bax accumulated in a time-dependent manner.

RT-PCR^[3]

Cell Line:	Lipopolysaccharides (HY-D1056)-stimulated Raw 264.7 cells
Concentration:	25,50,75,100 μM
Incubation Time:	30 min
Result:	Inhibited of LPS-induced NO and iNOS expression.br/> Inhibits transcription of iNOS. Had not affect phosphorylation of MAPKs. Inhibited NF-jB-binding activity and C/EBPb-binding activity.

體內(nèi)研究
(In Vivo)

8-Hydroxyquinoline (HOQ) (25-100 mg/kg，腹腔注射，單次給藥) 導(dǎo)致 CD1 小鼠中微核多色紅細(xì)胞(MPCE) 數(shù)量顯著增加^[4]。
8-Hydroxyquinoline (8-HQ) (0.3%，皮膚給藥，每周 4 次) 導(dǎo)致小鼠導(dǎo)致脫色毛發(fā)生長(zhǎng)，生長(zhǎng)模式隨時(shí)間變化^[5]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	CD1 mice^[4]
Dosage:	25,50,100 mg/kg
Administration:	Intraperitoneal injection (i.p.)
Result:	Resulted in a significant dose-related increase in the number of micronucleated polychromatic erythrocytes (MPCE) at the 24 h samplingtime for all doses tested.

Animal Model:	C57BL mice^[5]
Dosage:	0.3% 4 times weekly
Administration:	Skin administration
Result:	Caused depigmented hair to grow in patterns which change with time. Sufficiently frequent applications result in virtually complete depigmentation in young adult C57BL female mice, while single application causes isolated bands of depigmented hair.

分子量

145.16

Formula

C₉H₇NO

CAS 號(hào)

148-24-3

性狀

固體

顏色

Off-white to light brown

中文名稱

8-羥基喹啉；喔星

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

溶解性數(shù)據(jù)

細(xì)胞實(shí)驗(yàn)：

DMSO 中的溶解度 : 50 mg/mL (344.45 mM; 超聲助溶; 吸濕的 DMSO 對(duì)產(chǎn)品的溶解度有顯著影響，請(qǐng)使用新開封的 DMSO)

配制儲(chǔ)備液

濃度溶劑體積質(zhì)量	1 mg	5 mg	10 mg

1 mM	6.8889 mL	34.4447 mL	68.8895 mL
5 mM	1.3778 mL	6.8889 mL	13.7779 mL
10 mM	0.6889 mL	3.4445 mL	6.8889 mL

查看完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?年內(nèi)使用，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?年內(nèi)使用。

摩爾計(jì)算器
稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

濃度 _(start)

體積 _(start)

濃度 _(final)

體積 _(final)

動(dòng)物實(shí)驗(yàn)：

請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥方式選擇適當(dāng)?shù)娜芙夥桨浮?

以下溶解方案都請(qǐng)先按照 In Vitro 方式配制澄清的儲(chǔ)備液，再依次添加助溶劑：
——為保證實(shí)驗(yàn)結(jié)果的可靠性，澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；體內(nèi)實(shí)驗(yàn)的工作液，建議您現(xiàn)用現(xiàn)配，當(dāng)天使用；
以下溶劑前顯示的百分比是指該溶劑在您配制終溶液中的體積占比；如在配制過(guò)程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過(guò)加熱和/或超聲的方式助溶

方案一

請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (17.22 mM); 澄清溶液

此方案可獲得 ≥ 2.5 mg/mL（飽和度未知）的澄清溶液。
以 1 mL 工作液為例，取 100 μL 25.0 mg/mL 的澄清 DMSO 儲(chǔ)備液加到 400 μL PEG300 中，混合均勻；再向上述體系中加入 50 μL Tween-80，混合均勻；然后再繼續(xù)加入 450 μL 生理鹽水定容至 1 mL。
生理鹽水的配制：將 0.9 g 氯化鈉，溶解于 ddH?O 并定容至 100 mL，可以得到澄清透明的生理鹽水溶液。
方案二

請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (17.22 mM); 澄清溶液

此方案可獲得 ≥ 2.5 mg/mL（飽和度未知）的澄清溶液。
以 1 mL 工作液為例，取 100 μL 25.0 mg/mL 的澄清 DMSO 儲(chǔ)備液加到 900 μL 20% 的 SBE-β-CD 生理鹽水水溶液中，混合均勻。
2 g SBE-β-CD（磺丁基醚 β-環(huán)糊精）粉末定容于 10 mL 的生理鹽水中，完全溶解至澄清透明。
方案三

請(qǐng)依序添加每種溶劑： 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (17.22 mM); 澄清溶液

此方案可獲得 ≥ 2.5 mg/mL（飽和度未知）的澄清溶液，此方案實(shí)驗(yàn)周期在半個(gè)月以上的動(dòng)物實(shí)驗(yàn)酌情使用。
以 1 mL 工作液為例，取 100 μL 25.0 mg/mL 的澄清 DMSO 儲(chǔ)備液加到 900 μL玉米油中，混合均勻。

動(dòng)物溶解方案計(jì)算器

請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息：

給藥劑量

mg/kg

動(dòng)物的平均體重

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

只

由于實(shí)驗(yàn)過(guò)程有損耗，建議您多配一只動(dòng)物的量

請(qǐng)輸入您的動(dòng)物體內(nèi)配方組成：

DMSO +

Tween-80 +

Saline

如果您的動(dòng)物是免疫缺陷鼠或者體弱鼠，建議 DMSO 中的在最后工作液體系中的占比盡量不超過(guò) 2%。

方案所需 助溶劑 包括：DMSO，，均可在 MCE 網(wǎng)站選購(gòu)。，Tween 80，均可在 MCE 網(wǎng)站選購(gòu)。

計(jì)算結(jié)果

工作液所需濃度 : mg/mL

儲(chǔ)備液配制方法 : mg 藥物溶于 μL DMSO（母液濃度為 mg/mL）。

您所需的儲(chǔ)備液濃度超過(guò)該產(chǎn)品的實(shí)測(cè)溶解度，以下方案僅供參考，如有需要，請(qǐng)與 MCE 中國(guó)技術(shù)支持聯(lián)系。

動(dòng)物實(shí)驗(yàn)體內(nèi)工作液的配制方法 : 取 μL DMSO 儲(chǔ)備液，加入 μL 。 μL ，混合均勻至澄清，再加 μL Tween 80，混合均勻至澄清，再加 μL 生理鹽水。

連續(xù)給藥周期超過(guò)半月以上，請(qǐng)謹(jǐn)慎選擇該方案。

請(qǐng)確保第一步儲(chǔ)備液溶解至澄清狀態(tài)，從左到右依次添加助溶劑。您可采用超聲加熱（超聲清洗儀，建議頻次 20-40 kHz），渦旋吹打等方式輔助溶解。

純度 & 產(chǎn)品資料

純度: 99.99%

選擇批次：

Data Sheet (654 KB) SDS (890 KB)

COA (294 KB) HNMR (117 KB) RP-HPLC (247 KB) LCMS (314 KB)

產(chǎn)品使用指南 (1538 KB)

參考文獻(xiàn)

[1]. Lawung R, et.al. Repositioning of 8-hydroxyquinoline derivatives as a new promising candidate for combating multidrug resistant Neisseria gonorrhoeae. EXCLI J. 2018 Aug 23;17:840-846. [Content Brief]

[2]. 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells. J Biol Inorg Chem. 2010 Feb;15(2):259-69. [Content Brief]

[3]. Zhai S, et.al. Tumor cellular proteasome inhibition and growth suppression by [Content Brief]

[4]. Hamoud MA, et.al. Effects of quinoline and 8-hydroxyquinoline on mouse bone marrow erythrocytes as measured by the micronucleus assay. Teratog Carcinog Mutagen. 1989;9(2):111-8. [Content Brief]

[5]. Searle CE. The selective depigmenting action of 8-hydroxyquinoline on hair growth in the mouse. Br J Dermatol. 1972 May;86(5):472-80. [Content Brief]

8-Hydroxyquinoline 相關(guān)分類

完整儲(chǔ)備液配制表

可選溶劑	濃度溶劑體積質(zhì)量	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.8889 mL	34.4447 mL	68.8895 mL	172.2237 mL
	5 mM	1.3778 mL	6.8889 mL	13.7779 mL	34.4447 mL
	10 mM	0.6889 mL	3.4445 mL	6.8889 mL	17.2224 mL
	15 mM	0.4593 mL	2.2963 mL	4.5926 mL	11.4816 mL
	20 mM	0.3444 mL	1.7222 mL	3.4445 mL	8.6112 mL
	25 mM	0.2756 mL	1.3778 mL	2.7556 mL	6.8889 mL
	30 mM	0.2296 mL	1.1482 mL	2.2963 mL	5.7408 mL
	40 mM	0.1722 mL	0.8611 mL	1.7222 mL	4.3056 mL
	50 mM	0.1378 mL	0.6889 mL	1.3778 mL	3.4445 mL
	60 mM	0.1148 mL	0.5741 mL	1.1482 mL	2.8704 mL
	80 mM	0.0861 mL	0.4306 mL	0.8611 mL	2.1528 mL
	100 mM	0.0689 mL	0.3444 mL	0.6889 mL	1.7222 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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8-Hydroxyquinoline148-24-38-Quinolinol8-羥基喹啉喔星BacterialAntibioticInhibitorinhibitorinhibit

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