6 | 1184986-45-5 | CI-719-d6 | 吉非羅齊 d6 | PPAR | Cytochrome P450 | Peroxisome proliferator-activated receptors | CYPs | Inhibitor | inhibitor | inhibit"/>

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  2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR Cytochrome P450
  4. Gemfibrozil-d6

Gemfibrozil-d6 是 Gemfibrozil 的氘代物。Gemfibrozil 是一種 PPAR-α 激活劑，為一種降脂劑；Gemfibrozil 同時(shí)是 P450 的非選擇性抑制劑，對(duì) CYP2C9，2C19，2C8 和 1A2 的 Ki 值分別為 5.8，24，69 和 82 μM。

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Gemfibrozil-d<sub>6</sub> Chemical Structure

Gemfibrozil-d6 Chemical Structure

CAS No. : 1184986-45-5

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規(guī)格 價(jià)格 是否有貨
1 mg ￥1200
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Other Forms of Gemfibrozil-d6:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Gemfibrozil-d6 is the deuterium labeled Gemfibrozil. Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

256.37

Formula

C15H16D6O3
CAS 號(hào)
非標(biāo)記 CAS

25812-30-0
性狀

固體

顏色

Off-white to light yellow

中文名稱

吉非羅齊 d6
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: 98.00%

參考文獻(xiàn)

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  • 稀釋計(jì)算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Gemfibrozil-d6
目錄號(hào)：
HY-B0258S
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