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  4. Croscarmellose sodium

Croscarmellose sodium 是美國(guó)食品和藥物管理局 (FDA) 批準(zhǔn)的常用藥物添加劑。Croscarmellose sodium 在注射制劑中用作懸浮劑，以促進(jìn)水溶性差的化合物的溶解。Croscarmellose sodium 還作為粘合劑、助流劑和抗粘劑存在于片劑中，作為活性成分存在于散裝瀉藥中，并作為食品添加劑存在。Croscarmellose sodium 可用作藥用輔料，如崩解劑、崩解助劑。藥用輔料或藥用助劑，是指制藥過(guò)程中使用的除藥物成分以外的其他化學(xué)物質(zhì)。藥用輔料一般是指藥物制劑中的非活性成分，能提高藥物制劑的穩(wěn)定性、溶解性和加工性。藥用輔料還會(huì)影響共同給藥藥物的吸收、分布、代謝和消除 (ADME) 過(guò)程。

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Croscarmellose sodium Chemical Structure

Croscarmellose sodium Chemical Structure

CAS No. : 74811-65-7

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  • 生物活性

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生物活性

Croscarmellose sodium is a commonly used pharmaceutical additive approved by the US Food and Drug Administration (FDA). Croscarmellose sodium is used in injectable preparations as a suspending agent to promote solubilization of compounds with poor water solubility. Croscarmellose sodium is also present in tablets as binder, glidant and antiadherent, in bulk laxatives as active principle and as an additive in food products. Croscarmellose sodium can be used as an excipient, such as excipients, disintegrants, aids in disintegration. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

CAS 號(hào)
性狀

固體

顏色

White to off-white

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度 & 產(chǎn)品資料

參考文獻(xiàn)

Croscarmellose sodium 相關(guān)分類

  • 摩爾計(jì)算器

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
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