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  2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. XAV-939

XAV-939 (GMP) 是 GMP 級別的 XAV-939 (HY-15147)。GMP 級別的小分子可用做細胞療法中的輔助試劑。XAV-939 是一種 tankyrase 抑制劑。

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XAV-939 Chemical Structure

XAV-939 Chemical Structure

CAS No. : 284028-89-3

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規(guī)格 價格 是否有貨 數(shù)量
10 mg ￥8640
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Customer Review

  • 生物活性

  • 純度 & 產品資料

  • 參考文獻

生物活性

XAV-939 (GMP) is XAV-939 (HY-15347) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. XAV-939 is a tankyrase inhibitor[1].

體外研究
(In Vitro)

XAV-939 (GMP) (5 μM；2 μM，持續(xù) 3 天；1 μM) 誘導人多能干細胞 (hPSC) 向有絲分裂后皮質神經(jīng)元分化[1]。
XAV939 (GMP) 促進前部 CNS 識別[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR[1]

Cell Line: Human pluripotent stem cells (hPSCs)
Concentration: 5 μM, 2 μM, 1 μM
Incubation Time: 3 days
Result: Showed downregulation of the pluripotency marker OCT4 and induction of neural and neuronal markers PAX6, FOXG1 and DCX, as well as markers of early born cortical neurons, including TBR1 (preplate, subplate and layer VI) and REELIN, in LSB+X/P/S/D conditions.
分子量

312.31

Formula

C14H11F3N2OS
CAS 號
性狀

固體

顏色

White to off-white

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產品資料
參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產品名稱：
XAV-939
目錄號：
HY-15147G
需求量：