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  2. PROTAC Antibody-drug Conjugate/ADC Related
  3. PROTAC Linkers ADC Linker
  4. m-PEG6-NHS ester

m-PEG6-NHS ester 是一種不可降解 (non-cleavable) 的含 6 個單元 PEG 的 ADC linker，可用于合成抗體偶聯活性分子 (ADC)。m-PEG6-NHS ester 是一種 PROTAC linker，屬于 PEG/Alkyl/ether 類，可用于合成 PROTAC 分子。

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m-PEG6-NHS ester Chemical Structure

m-PEG6-NHS ester Chemical Structure

CAS No. : 1449390-12-8

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規(guī)格 價格 是否有貨
50 mg ￥385
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100 mg ￥577
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250 mg ￥980
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1 g ￥2645
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Customer Review

  • 生物活性

  • 純度 & 產品資料

  • 參考文獻

生物活性

m-PEG6-NHS ester is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target

PEGs

 

Alkyl/ether

 

Non-cleavable Linker

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

421.44

Formula

C18H31NO10
CAS 號
性狀

液體（密度：1.21±0.1 g/cm3）

顏色

Colorless to light yellow

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產品資料

純度: ≥97.0%

參考文獻

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  • 稀釋計算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
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產品名稱：
m-PEG6-NHS ester
目錄號：
HY-133066
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