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  2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Fmoc-NH-PEG5-CH2COOH

Fmoc-NH-PEG5-CH2COOH 是一種可降解的ADC linker，用于抗體活性分子偶聯(lián)物 (ADC) 合成。Fmoc-NH-PEG5-CH2COOH 也是一種基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。

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Fmoc-NH-PEG5-CH2COOH Chemical Structure

Fmoc-NH-PEG5-CH2COOH Chemical Structure

CAS No. : 635287-26-2

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規(guī)格 價格 是否有貨
50 mg ￥240
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100 mg ￥364
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250 mg ￥559
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1 g ￥890
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5 g ￥4022
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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Cleavable Linker

 

Alkyl/ether

 

PEGs

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

517.57

Formula

C27H35NO9
CAS 號
性狀

粘稠液體

顏色

Colorless to light yellow

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
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產(chǎn)品名稱：
Fmoc-NH-PEG5-CH2COOH
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HY-133062
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