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  2. Immunology/Inflammation
  3. Interleukin Related
  4. Basiliximab

Basiliximab  (Synonyms: 巴利昔單抗; CHI 621)

目錄號: HY-108852 純度: 95.0%
COA

Basiliximab (CHI 621) 是一種重組嵌合鼠/人 IgG1 單克隆抗白細胞介素 2 受體 (interleukin-2 receptor) 抗體。Basiliximab 可用于腎移植研究。

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CAS No. : 179045-86-4

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥4000
In-stock
5 mg ￥9075
In-stock
10 mg ￥12238
In-stock
25 mg ￥18125
In-stock
50 mg ￥24500
In-stock
100 mg   詢價  
200 mg   詢價  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation[1].

同型

Human IgG1 kappa
推薦同型對照抗體
種屬

Chimeric
IC50 & Target

Interleukin-2 receptor[1]
體外研究
(In Vitro)

Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα[1].
Basiliximab binds only to activated lymphocytes and macrophages/monocytes[3].
Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia[2]
Dosage: 0.07 mg/rat
Administration: IV infusion, once
Result: Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
Clinical Trial
CAS 號
性狀

液體

顏色

Colorless to light yellow

中文名稱

巴利昔單抗
運輸條件

Shipping with dry ice.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
純度 & 產(chǎn)品資料
參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Basiliximab
目錄號：
HY-108852
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