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  3. Perfluorodecalin

Perfluorodecalin  (Synonyms: 全氟萘烷; PP 5; Perfluorodecahydronaphthalene)

目錄號(hào): HY-108298 純度: ≥98.0%
COA 產(chǎn)品使用指南

Perfluorodecalin 液體大量用于玻璃體視網(wǎng)膜手術(shù)。在兔子的情況下,填塞超過兩天的 Perfluorodecalin 對(duì)視網(wǎng)膜有害。全氟萘烷可用于巨大視網(wǎng)膜撕裂的研究。Perfluorodecalin 是一種無毒、不易燃、熱穩(wěn)定、不具備生物累積性的 O2 載體,可用作人造血液。Perfluorodecalin 可增強(qiáng)骨再生和細(xì)胞活力。

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Perfluorodecalin Chemical Structure

Perfluorodecalin Chemical Structure

CAS No. : 306-94-5

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5].

體外研究
(In Vitro)

Perfluorodecalin 可延長細(xì)胞在厭氧環(huán)境中的存活時(shí)間,增強(qiáng)骨水泥的放射性不透性、可注射性、內(nèi)聚力和骨再生活性[4]。 Perfluorodecalin (10% v/v) 可改善封裝胰島移植過程中的缺氧情況并提高細(xì)胞活力[5]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[5]

Cell Line: BM cells
Concentration:
Incubation Time: 21 days
Result: Increased number of BM cells.

RT-PCR[5]

Cell Line: islets
Concentration: 10% v/v
Incubation Time:
Result: Decreased HIF-1α expression and increased VEGF expression.
體內(nèi)研究
(In Vivo)

Perfluorodecalin (1.1-1.5 ml/eye) 會(huì)引起白化兔子的視網(wǎng)膜損傷和炎癥[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Albino rabbits[2]
Dosage: 1.1-1.5 ml for each eye
Administration: injection into vitreous cavity
Result: Induced appearance of foam cells, preretinal membranes, and the interface necrosis.
分子量

462.08

Formula

C10F18

CAS 號(hào)
性狀

液體(密度:1.9456 g/cm3

顏色

Colorless to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn): 

DMSO 中的溶解度 : 100 mg/mL (216.41 mM; 超聲助溶 (<60°C); 吸濕的 DMSO 對(duì)產(chǎn)品的溶解度有顯著影響,請(qǐng)使用新開封的 DMSO)

配制儲(chǔ)備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 2.1641 mL 10.8206 mL 21.6413 mL
5 mM 0.4328 mL 2.1641 mL 4.3283 mL
查看完整儲(chǔ)備液配制表
  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物溶解方案計(jì)算器
請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息:

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

由于實(shí)驗(yàn)過程有損耗,建議您多配一只動(dòng)物的量
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻(xiàn)

Perfluorodecalin 相關(guān)分類

完整儲(chǔ)備液配制表

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1641 mL 10.8206 mL 21.6413 mL 54.1032 mL
5 mM 0.4328 mL 2.1641 mL 4.3283 mL 10.8206 mL
10 mM 0.2164 mL 1.0821 mL 2.1641 mL 5.4103 mL
15 mM 0.1443 mL 0.7214 mL 1.4428 mL 3.6069 mL
20 mM 0.1082 mL 0.5410 mL 1.0821 mL 2.7052 mL
25 mM 0.0866 mL 0.4328 mL 0.8657 mL 2.1641 mL
30 mM 0.0721 mL 0.3607 mL 0.7214 mL 1.8034 mL
40 mM 0.0541 mL 0.2705 mL 0.5410 mL 1.3526 mL
50 mM 0.0433 mL 0.2164 mL 0.4328 mL 1.0821 mL
60 mM 0.0361 mL 0.1803 mL 0.3607 mL 0.9017 mL
80 mM 0.0271 mL 0.1353 mL 0.2705 mL 0.6763 mL
100 mM 0.0216 mL 0.1082 mL 0.2164 mL 0.5410 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Perfluorodecalin
目錄號(hào):
HY-108298
需求量: