- 抑制劑
- 化合物庫
- 抗體
- 生物試劑
- 新產(chǎn)品
- 聯(lián)系我們
別名: NSC 628503,RP56976 中文名稱:多西他賽,多烯紫杉醇
Docetaxel多西他賽是一種taxol類似物,是一種microtubules解聚抑制劑,通過結(jié)合于穩(wěn)定的微管發(fā)揮作用。
Docetaxel Chemical Structure
CAS: 114977-28-5
細胞系 | 實驗類型 | 給藥濃度 | 孵育時間 | 活性描述 | 文獻信息 |
---|---|---|---|---|---|
NUGC-3 | Growth Inhibition Assay | IC50=0.00308 μM | SANGER | ||
BB65-RCC | Growth Inhibition Assay | IC50=0.00308 μM | SANGER | ||
U031 | Growth Inhibition Assay | IC50=0.00307 μM | SANGER | ||
HEC-1 | Growth Inhibition Assay | IC50=0.00303 μM | SANGER | ||
DU-4475 | Growth Inhibition Assay | IC50=0.00302 μM | SANGER | ||
DEL | Growth Inhibition Assay | IC50=0.00301 μM | SANGER | ||
CP66-MEL | Growth Inhibition Assay | IC50=0.003 μM | SANGER | ||
EW-1 | Growth Inhibition Assay | IC50=0.00298 μM | SANGER | ||
GP5d | Growth Inhibition Assay | IC50=0.00296 μM | SANGER | ||
SW1088 | Growth Inhibition Assay | IC50=0.00295 μM | SANGER | ||
DOK | Growth Inhibition Assay | IC50=0.00294 μM | SANGER | ||
LCLC-103H | Growth Inhibition Assay | IC50=0.00293 μM | SANGER | ||
SW962 | Growth Inhibition Assay | IC50=0.00293 μM | SANGER | ||
SKG-IIIa | Growth Inhibition Assay | IC50=0.00286 μM | SANGER | ||
NCI-H209 | Growth Inhibition Assay | IC50=0.00286 μM | SANGER | ||
HTC-C3 | Growth Inhibition Assay | IC50=0.00285 μM | SANGER | ||
HT-3 | Growth Inhibition Assay | IC50=0.00282 μM | SANGER | ||
JEG-3 | Growth Inhibition Assay | IC50=0.00282 μM | SANGER | ||
RPMI-8866 | Growth Inhibition Assay | IC50=0.00281 μM | SANGER | ||
MDA-MB-361 | Growth Inhibition Assay | IC50=0.00281 μM | SANGER | ||
HT-29 | Growth Inhibition Assay | IC50=0.0028 μM | SANGER | ||
KYSE-270 | Growth Inhibition Assay | IC50=0.00278 μM | SANGER | ||
ES3 | Growth Inhibition Assay | IC50=0.00277 μM | SANGER | ||
HCC70 | Growth Inhibition Assay | IC50=0.00277 μM | SANGER | ||
SW1417 | Growth Inhibition Assay | IC50=0.00276 μM | SANGER | ||
MDA-MB-415 | Growth Inhibition Assay | IC50=0.00274 μM | SANGER | ||
Hs-578-T | Growth Inhibition Assay | IC50=0.00272 μM | SANGER | ||
CAL-51 | Growth Inhibition Assay | IC50=0.00271 μM | SANGER | ||
C-33-A | Growth Inhibition Assay | IC50=0.00266 μM | SANGER | ||
A388 | Growth Inhibition Assay | IC50=0.00265 μM | SANGER | ||
SNU-387 | Growth Inhibition Assay | IC50=0.00261 μM | SANGER | ||
NCI-H1437 | Growth Inhibition Assay | IC50=0.0026 μM | SANGER | ||
OC-314 | Growth Inhibition Assay | IC50=0.00256 μM | SANGER | ||
TE-10 | Growth Inhibition Assay | IC50=0.00254 μM | SANGER | ||
VMRC-RCZ | Growth Inhibition Assay | IC50=0.00252 μM | SANGER | ||
BxPC-3 | Growth Inhibition Assay | IC50=0.00251 μM | SANGER | ||
U251 | Growth Inhibition Assay | IC50=0.0025 μM | SANGER | ||
KGN | Growth Inhibition Assay | IC50=0.00247 μM | SANGER | ||
HCE-4 | Growth Inhibition Assay | IC50=0.00247 μM | SANGER | ||
RPMI-2650 | Growth Inhibition Assay | IC50=0.00246 μM | SANGER | ||
NCI-H446 | Growth Inhibition Assay | IC50=0.00243 μM | SANGER | ||
A673 | Growth Inhibition Assay | IC50=0.00235 μM | SANGER | ||
J-RT3-T3-5 | Growth Inhibition Assay | IC50=0.00235 μM | SANGER | ||
SK-HEP-1 | Growth Inhibition Assay | IC50=0.00234 μM | SANGER | ||
SK-MES-1 | Growth Inhibition Assay | IC50=0.00233 μM | SANGER | ||
JVM-3 | Growth Inhibition Assay | IC50=0.00233 μM | SANGER | ||
TYK-nu | Growth Inhibition Assay | IC50=0.00232 μM | SANGER | ||
GOTO | Growth Inhibition Assay | IC50=0.00227 μM | SANGER | ||
SK-UT-1 | Growth Inhibition Assay | IC50=0.00226 μM | SANGER | ||
NCI-H650 | Growth Inhibition Assay | IC50=0.00225 μM | SANGER | ||
IST-MEL1 | Growth Inhibition Assay | IC50=0.00225 μM | SANGER | ||
BFTC-909 | Growth Inhibition Assay | IC50=0.00225 μM | SANGER | ||
RXF393 | Growth Inhibition Assay | IC50=0.00222 μM | SANGER | ||
COR-L23 | Growth Inhibition Assay | IC50=0.0022 μM | SANGER | ||
NCI-H1581 | Growth Inhibition Assay | IC50=0.00217 μM | SANGER | ||
NCI-H2452 | Growth Inhibition Assay | IC50=0.00216 μM | SANGER | ||
TE-1 | Growth Inhibition Assay | IC50=0.00216 μM | SANGER | ||
SW756 | Growth Inhibition Assay | IC50=0.00216 μM | SANGER | ||
BHY | Growth Inhibition Assay | IC50=0.00216 μM | SANGER | ||
EFM-19 | Growth Inhibition Assay | IC50=0.00215 μM | SANGER | ||
BB49-HNC | Growth Inhibition Assay | IC50=0.00212 μM | SANGER | ||
OVCAR-8 | Growth Inhibition Assay | IC50=0.00212 μM | SANGER | ||
PC-14 | Growth Inhibition Assay | IC50=0.00209 μM | SANGER | ||
SK-MEL-28 | Growth Inhibition Assay | IC50=0.00203 μM | SANGER | ||
OVCAR-5 | Growth Inhibition Assay | IC50=0.00199 μM | SANGER | ||
M059J | Growth Inhibition Assay | IC50=0.00198 μM | SANGER | ||
NCI-SNU-1 | Growth Inhibition Assay | IC50=0.00197 μM | SANGER | ||
H4 | Growth Inhibition Assay | IC50=0.00196 μM | SANGER | ||
SK-PN-DW | Growth Inhibition Assay | IC50=0.00194 μM | SANGER | ||
CTB-1 | Growth Inhibition Assay | IC50=0.00192 μM | SANGER | ||
NCI-H1048 | Growth Inhibition Assay | IC50=0.00192 μM | SANGER | ||
M14 | Growth Inhibition Assay | IC50=0.00191 μM | SANGER | ||
MHH-PREB-1 | Growth Inhibition Assay | IC50=0.00189 μM | SANGER | ||
NB17 | Growth Inhibition Assay | IC50=0.00189 μM | SANGER | ||
SBC-5 | Growth Inhibition Assay | IC50=0.00187 μM | SANGER | ||
NCI-H2122 | Growth Inhibition Assay | IC50=0.00184 μM | SANGER | ||
647-V | Growth Inhibition Assay | IC50=0.00184 μM | SANGER | ||
Becker | Growth Inhibition Assay | IC50=0.00183 μM | SANGER | ||
C2BBe1 | Growth Inhibition Assay | IC50=0.00182 μM | SANGER | ||
KALS-1 | Growth Inhibition Assay | IC50=0.00181 μM | SANGER | ||
AU565 | Growth Inhibition Assay | IC50=0.00181 μM | SANGER | ||
HCT-116 | Growth Inhibition Assay | IC50=0.00181 μM | SANGER | ||
GCT | Growth Inhibition Assay | IC50=0.0018 μM | SANGER | ||
DB | Growth Inhibition Assay | IC50=0.00178 μM | SANGER | ||
SK-NEP-1 | Growth Inhibition Assay | IC50=0.00176 μM | SANGER | ||
NCI-H526 | Growth Inhibition Assay | IC50=0.00176 μM | SANGER | ||
U-2-OS | Growth Inhibition Assay | IC50=0.00175 μM | SANGER | ||
MV-4-11 | Growth Inhibition Assay | IC50=0.00174 μM | SANGER | ||
EoL-1-cell | Growth Inhibition Assay | IC50=0.00173 μM | SANGER | ||
D-247MG | Growth Inhibition Assay | IC50=0.00173 μM | SANGER | ||
697 | Growth Inhibition Assay | IC50=0.00172 μM | SANGER | ||
SK-MEL-2 | Growth Inhibition Assay | IC50=0.0017 μM | SANGER | ||
ME-180 | Growth Inhibition Assay | IC50=0.00169 μM | SANGER | ||
SW13 | Growth Inhibition Assay | IC50=0.00169 μM | SANGER | ||
D-336MG | Growth Inhibition Assay | IC50=0.00169 μM | SANGER | ||
EW-11 | Growth Inhibition Assay | IC50=0.00169 μM | SANGER | ||
Saos-2 | Growth Inhibition Assay | IC50=0.00168 μM | SANGER | ||
CAL-39 | Growth Inhibition Assay | IC50=0.00163 μM | SANGER | ||
A172 | Growth Inhibition Assay | IC50=0.00163 μM | SANGER | ||
MCF7 | Growth Inhibition Assay | IC50=0.00161 μM | SANGER | ||
NCI-H1703 | Growth Inhibition Assay | IC50=0.00157 μM | SANGER | ||
KP-4 | Growth Inhibition Assay | IC50=0.00156 μM | SANGER | ||
ES4 | Growth Inhibition Assay | IC50=0.00155 μM | SANGER | ||
23132-87 | Growth Inhibition Assay | IC50=0.00155 μM | SANGER | ||
PANC-03-27 | Growth Inhibition Assay | IC50=0.00154 μM | SANGER | ||
MG-63 | Growth Inhibition Assay | IC50=0.00151 μM | SANGER | ||
LB831-BLC | Growth Inhibition Assay | IC50=0.00148 μM | SANGER | ||
A427 | Growth Inhibition Assay | IC50=0.00148 μM | SANGER | ||
TI-73 | Growth Inhibition Assay | IC50=0.00144 μM | SANGER | ||
KS-1 | Growth Inhibition Assay | IC50=0.00144 μM | SANGER | ||
LCLC-97TM1 | Growth Inhibition Assay | IC50=0.00144 μM | SANGER | ||
KYSE-450 | Growth Inhibition Assay | IC50=0.00143 μM | SANGER | ||
HD-MY-Z | Growth Inhibition Assay | IC50=0.00141 μM | SANGER | ||
EW-16 | Growth Inhibition Assay | IC50=0.00135 μM | SANGER | ||
KYSE-180 | Growth Inhibition Assay | IC50=0.00135 μM | SANGER | ||
SAS | Growth Inhibition Assay | IC50=0.00134 μM | SANGER | ||
SCC-9 | Growth Inhibition Assay | IC50=0.00132 μM | SANGER | ||
CAMA-1 | Growth Inhibition Assay | IC50=0.00131 μM | SANGER | ||
D-423MG | Growth Inhibition Assay | IC50=0.0013 μM | SANGER | ||
SW982 | Growth Inhibition Assay | IC50=0.00127 μM | SANGER | ||
G-401 | Growth Inhibition Assay | IC50=0.00127 μM | SANGER | ||
KYSE-410 | Growth Inhibition Assay | IC50=0.00124 μM | SANGER | ||
H9 | Growth Inhibition Assay | IC50=0.00124 μM | SANGER | ||
SF268 | Growth Inhibition Assay | IC50=0.00121 μM | SANGER | ||
A375 | Growth Inhibition Assay | IC50=0.00121 μM | SANGER | ||
LK-2 | Growth Inhibition Assay | IC50=0.00121 μM | SANGER | ||
RT-112 | Growth Inhibition Assay | IC50=0.00119 μM | SANGER | ||
MZ1-PC | Growth Inhibition Assay | IC50=0.00118 μM | SANGER | ||
HCC1806 | Growth Inhibition Assay | IC50=0.00118 μM | SANGER | ||
T98G | Growth Inhibition Assay | IC50=0.00117 μM | SANGER | ||
KINGS-1 | Growth Inhibition Assay | IC50=0.00117 μM | SANGER | ||
LOXIMVI | Growth Inhibition Assay | IC50=0.00116 μM | SANGER | ||
RERF-LC-MS | Growth Inhibition Assay | IC50=0.00113 μM | SANGER | ||
KNS-62 | Growth Inhibition Assay | IC50=0.00112 μM | SANGER | ||
EPLC-272H | Growth Inhibition Assay | IC50=0.00111 μM | SANGER | ||
LNCaP-Clone-FGC | Growth Inhibition Assay | IC50=0.0011 μM | SANGER | ||
NBsusSR | Growth Inhibition Assay | IC50=0.0011 μM | SANGER | ||
NB13 | Growth Inhibition Assay | IC50=0.00107 μM | SANGER | ||
TE-5 | Growth Inhibition Assay | IC50=0.00106 μM | SANGER | ||
VM-CUB-1 | Growth Inhibition Assay | IC50=0.00105 μM | SANGER | ||
BB30-HNC | Growth Inhibition Assay | IC50=0.00105 μM | SANGER | ||
NCI-H1792 | Growth Inhibition Assay | IC50=0.00104 μM | SANGER | ||
CAL-33 | Growth Inhibition Assay | IC50=0.00104 μM | SANGER | ||
EFO-27 | Growth Inhibition Assay | IC50=0.00102 μM | SANGER | ||
BPH-1 | Growth Inhibition Assay | IC50=0.00102 μM | SANGER | ||
SW48 | Growth Inhibition Assay | IC50=0.00101 μM | SANGER | ||
RKO | Growth Inhibition Assay | IC50=0.000989 μM | SANGER | ||
CHL-1 | Growth Inhibition Assay | IC50=0.000958 μM | SANGER | ||
BCPAP | Growth Inhibition Assay | IC50=0.000947 μM | SANGER | ||
D-263MG | Growth Inhibition Assay | IC50=0.000947 μM | SANGER | ||
GMS-10 | Growth Inhibition Assay | IC50=0.000941 μM | SANGER | ||
KYSE-140 | Growth Inhibition Assay | IC50=0.000933 μM | SANGER | ||
ES5 | Growth Inhibition Assay | IC50=0.00091 μM | SANGER | ||
Detroit562 | Growth Inhibition Assay | IC50=0.000902 μM | SANGER | ||
A549 | Growth Inhibition Assay | IC50=0.000882 μM | SANGER | ||
8505C | Growth Inhibition Assay | IC50=0.000854 μM | SANGER | ||
KYSE-510 | Growth Inhibition Assay | IC50=0.00084 μM | SANGER | ||
SW954 | Growth Inhibition Assay | IC50=0.000823 μM | SANGER | ||
YH-13 | Growth Inhibition Assay | IC50=0.000791 μM | SANGER | ||
HOS | Growth Inhibition Assay | IC50=0.000782 μM | SANGER | ||
K5 | Growth Inhibition Assay | IC50=0.000778 μM | SANGER | ||
NTERA-S-cl-D1 | Growth Inhibition Assay | IC50=0.000773 μM | SANGER | ||
ES1 | Growth Inhibition Assay | IC50=0.00077 μM | SANGER | ||
LXF-289 | Growth Inhibition Assay | IC50=0.000758 μM | SANGER | ||
HN | Growth Inhibition Assay | IC50=0.000758 μM | SANGER | ||
HSC-2 | Growth Inhibition Assay | IC50=0.000755 μM | SANGER | ||
P12-ICHIKAWA | Growth Inhibition Assay | IC50=0.000745 μM | SANGER | ||
EW-3 | Growth Inhibition Assay | IC50=0.000745 μM | SANGER | ||
SCC-4 | Growth Inhibition Assay | IC50=0.000739 μM | SANGER | ||
CHP-212 | Growth Inhibition Assay | IC50=0.00073 μM | SANGER | ||
Ca-Ski | Growth Inhibition Assay | IC50=0.000728 μM | SANGER | ||
YKG-1 | Growth Inhibition Assay | IC50=0.000707 μM | SANGER | ||
G-402 | Growth Inhibition Assay | IC50=0.000706 μM | SANGER | ||
Daoy | Growth Inhibition Assay | IC50=0.0007 μM | SANGER | ||
MHH-ES-1 | Growth Inhibition Assay | IC50=0.0007 μM | SANGER | ||
PA-1 | Growth Inhibition Assay | IC50=0.000687 μM | SANGER | ||
SCC-25 | Growth Inhibition Assay | IC50=0.00068 μM | SANGER | ||
TE-9 | Growth Inhibition Assay | IC50=0.000676 μM | SANGER | ||
DMS-273 | Growth Inhibition Assay | IC50=0.000674 μM | SANGER | ||
PFSK-1 | Growth Inhibition Assay | IC50=0.000657 μM | SANGER | ||
639-V | Growth Inhibition Assay | IC50=0.000647 μM | SANGER | ||
SJSA-1 | Growth Inhibition Assay | IC50=0.000615 μM | SANGER | ||
EC-GI-10 | Growth Inhibition Assay | IC50=0.000592 μM | SANGER | ||
8-MG-BA | Growth Inhibition Assay | IC50=0.000589 μM | SANGER | ||
SW780 | Growth Inhibition Assay | IC50=0.000587 μM | SANGER | ||
PSN1 | Growth Inhibition Assay | IC50=0.000581 μM | SANGER | ||
NCI-H720 | Growth Inhibition Assay | IC50=0.00058 μM | SANGER | ||
TE-11 | Growth Inhibition Assay | IC50=0.000569 μM | SANGER | ||
NEC8 | Growth Inhibition Assay | IC50=0.000561 μM | SANGER | ||
ETK-1 | Growth Inhibition Assay | IC50=0.000558 μM | SANGER | ||
A2058 | Growth Inhibition Assay | IC50=0.000544 μM | SANGER | ||
CGTH-W-1 | Growth Inhibition Assay | IC50=0.000542 μM | SANGER | ||
GI-1 | Growth Inhibition Assay | IC50=0.000528 μM | SANGER | ||
NMC-G1 | Growth Inhibition Assay | IC50=0.000517 μM | SANGER | ||
HT-1080 | Growth Inhibition Assay | IC50=0.000501 μM | SANGER | ||
FTC-133 | Growth Inhibition Assay | IC50=0.000489 μM | SANGER | ||
MC-IXC | Growth Inhibition Assay | IC50=0.000479 μM | SANGER | ||
HGC-27 | Growth Inhibition Assay | IC50=0.000471 μM | SANGER | ||
SW1710 | Growth Inhibition Assay | IC50=0.000466 μM | SANGER | ||
RPMI-7951 | Growth Inhibition Assay | IC50=0.000448 μM | SANGER | ||
SBC-1 | Growth Inhibition Assay | IC50=0.00043 μM | SANGER | ||
Ca9-22 | Growth Inhibition Assay | IC50=0.000423 μM | SANGER | ||
GAMG | Growth Inhibition Assay | IC50=0.000416 μM | SANGER | ||
ES7 | Growth Inhibition Assay | IC50=0.000389 μM | SANGER | ||
COLO-800 | Growth Inhibition Assay | IC50=0.000388 μM | SANGER | ||
RH-1 | Growth Inhibition Assay | IC50=0.000386 μM | SANGER | ||
VA-ES-BJ | Growth Inhibition Assay | IC50=0.000375 μM | SANGER | ||
TE-8 | Growth Inhibition Assay | IC50=0.000366 μM | SANGER | ||
CAL-27 | Growth Inhibition Assay | IC50=0.000339 μM | SANGER | ||
NCI-H510A | Growth Inhibition Assay | IC50=0.000336 μM | SANGER | ||
HuO-3N1 | Growth Inhibition Assay | IC50=0.000302 μM | SANGER | ||
SF539 | Growth Inhibition Assay | IC50=0.000302 μM | SANGER | ||
HO-1-N-1 | Growth Inhibition Assay | IC50=0.000281 μM | SANGER | ||
A498 | Growth Inhibition Assay | IC50=0.000278 μM | SANGER | ||
BFTC-905 | Growth Inhibition Assay | IC50=0.000268 μM | SANGER | ||
ES8 | Growth Inhibition Assay | IC50=0.00026 μM | SANGER | ||
NB14 | Growth Inhibition Assay | IC50=0.00026 μM | SANGER | ||
KOSC-2 | Growth Inhibition Assay | IC50=0.000255 μM | SANGER | ||
HSC-4 | Growth Inhibition Assay | IC50=0.000239 μM | SANGER | ||
GT3TKB | Growth Inhibition Assay | IC50=0.000232 μM | SANGER | ||
CAL-62 | Growth Inhibition Assay | IC50=0.000185 μM | SANGER | ||
D-566MG | Growth Inhibition Assay | IC50=0.000182 μM | SANGER | ||
ESS-1 | Growth Inhibition Assay | IC50=0.000179 μM | SANGER | ||
HCE-T | Growth Inhibition Assay | IC50=0.000162 μM | SANGER | ||
NCI-H292 | Growth Inhibition Assay | IC50=0.000159 μM | SANGER | ||
HT-144 | Growth Inhibition Assay | IC50=0.000157 μM | SANGER | ||
5637 | Growth Inhibition Assay | IC50=0.000143 μM | SANGER | ||
HSC-3 | Growth Inhibition Assay | IC50=0.000132 μM | SANGER | ||
IST-SL1 | Growth Inhibition Assay | IC50=0.00312 μM | SANGER | ||
LS-411N | Growth Inhibition Assay | IC50=0.00314 μM | SANGER | ||
22RV1 | Growth Inhibition Assay | IC50=0.00315 μM | SANGER | ||
MKN28 | Growth Inhibition Assay | IC50=0.00317 μM | SANGER | ||
ONS-76 | Growth Inhibition Assay | IC50=0.00322 μM | SANGER | ||
SH-4 | Growth Inhibition Assay | IC50=0.00322 μM | SANGER | ||
MIA-PaCa-2 | Growth Inhibition Assay | IC50=0.00324 μM | SANGER | ||
CaR-1 | Growth Inhibition Assay | IC50=0.00327 μM | SANGER | ||
AGS | Growth Inhibition Assay | IC50=0.00328 μM | SANGER | ||
SF126 | Growth Inhibition Assay | IC50=0.00329 μM | SANGER | ||
UACC-62 | Growth Inhibition Assay | IC50=0.0033 μM | SANGER | ||
NCI-H28 | Growth Inhibition Assay | IC50=0.00334 μM | SANGER | ||
A2780 | Growth Inhibition Assay | IC50=0.00335 μM | SANGER | ||
CTV-1 | Growth Inhibition Assay | IC50=0.00337 μM | SANGER | ||
LC-2-ad | Growth Inhibition Assay | IC50=0.0034 μM | SANGER | ||
NCI-H1770 | Growth Inhibition Assay | IC50=0.00342 μM | SANGER | ||
HuO9 | Growth Inhibition Assay | IC50=0.00346 μM | SANGER | ||
U-266 | Growth Inhibition Assay | IC50=0.00348 μM | SANGER | ||
MLMA | Growth Inhibition Assay | IC50=0.00355 μM | SANGER | ||
U-87-MG | Growth Inhibition Assay | IC50=0.00355 μM | SANGER | ||
GI-ME-N | Growth Inhibition Assay | IC50=0.00358 μM | SANGER | ||
HL-60 | Growth Inhibition Assay | IC50=0.00359 μM | SANGER | ||
EGI-1 | Growth Inhibition Assay | IC50=0.00362 μM | SANGER | ||
NCI-H23 | Growth Inhibition Assay | IC50=0.00364 μM | SANGER | ||
NCI-H226 | Growth Inhibition Assay | IC50=0.00368 μM | SANGER | ||
NCI-H520 | Growth Inhibition Assay | IC50=0.00372 μM | SANGER | ||
L-363 | Growth Inhibition Assay | IC50=0.00376 μM | SANGER | ||
CAL-12T | Growth Inhibition Assay | IC50=0.00376 μM | SANGER | ||
BT-20 | Growth Inhibition Assay | IC50=0.00376 μM | SANGER | ||
SNB75 | Growth Inhibition Assay | IC50=0.00381 μM | SANGER | ||
A4-Fuk | Growth Inhibition Assay | IC50=0.0039 μM | SANGER | ||
BE-13 | Growth Inhibition Assay | IC50=0.00393 μM | SANGER | ||
NCI-H1395 | Growth Inhibition Assay | IC50=0.00396 μM | SANGER | ||
SW620 | Growth Inhibition Assay | IC50=0.00397 μM | SANGER | ||
KNS-81-FD | Growth Inhibition Assay | IC50=0.00399 μM | SANGER | ||
RD | Growth Inhibition Assay | IC50=0.004 μM | SANGER | ||
HLE | Growth Inhibition Assay | IC50=0.00405 μM | SANGER | ||
OVCAR-3 | Growth Inhibition Assay | IC50=0.00407 μM | SANGER | ||
KM12 | Growth Inhibition Assay | IC50=0.00408 μM | SANGER | ||
HCC2998 | Growth Inhibition Assay | IC50=0.00408 μM | SANGER | ||
D-502MG | Growth Inhibition Assay | IC50=0.0041 μM | SANGER | ||
KNS-42 | Growth Inhibition Assay | IC50=0.00412 μM | SANGER | ||
LS-123 | Growth Inhibition Assay | IC50=0.00425 μM | SANGER | ||
SiHa | Growth Inhibition Assay | IC50=0.0043 μM | SANGER | ||
T47D | Growth Inhibition Assay | IC50=0.00431 μM | SANGER | ||
EW-24 | Growth Inhibition Assay | IC50=0.00433 μM | SANGER | ||
CAL-120 | Growth Inhibition Assay | IC50=0.00435 μM | SANGER | ||
JAR | Growth Inhibition Assay | IC50=0.00437 μM | SANGER | ||
QIMR-WIL | Growth Inhibition Assay | IC50=0.00438 μM | SANGER | ||
OCUB-M | Growth Inhibition Assay | IC50=0.00438 μM | SANGER | ||
Calu-6 | Growth Inhibition Assay | IC50=0.00447 μM | SANGER | ||
MDA-MB-453 | Growth Inhibition Assay | IC50=0.00451 μM | SANGER | ||
MKN45 | Growth Inhibition Assay | IC50=0.00453 μM | SANGER | ||
ECC10 | Growth Inhibition Assay | IC50=0.0046 μM | SANGER | ||
RVH-421 | Growth Inhibition Assay | IC50=0.00461 μM | SANGER | ||
TGBC11TKB | Growth Inhibition Assay | IC50=0.00469 μM | SANGER | ||
MOLT-4 | Growth Inhibition Assay | IC50=0.00471 μM | SANGER | ||
LN-405 | Growth Inhibition Assay | IC50=0.00482 μM | SANGER | ||
S-117 | Growth Inhibition Assay | IC50=0.00486 μM | SANGER | ||
RPMI-8226 | Growth Inhibition Assay | IC50=0.00497 μM | SANGER | ||
KYSE-150 | Growth Inhibition Assay | IC50=0.00499 μM | SANGER | ||
NCI-H1666 | Growth Inhibition Assay | IC50=0.00505 μM | SANGER | ||
Mewo | Growth Inhibition Assay | IC50=0.00505 μM | SANGER | ||
AN3-CA | Growth Inhibition Assay | IC50=0.00507 μM | SANGER | ||
COLO-680N | Growth Inhibition Assay | IC50=0.00508 μM | SANGER | ||
FADU | Growth Inhibition Assay | IC50=0.0051 μM | SANGER | ||
GB-1 | Growth Inhibition Assay | IC50=0.00511 μM | SANGER | ||
KASUMI-1 | Growth Inhibition Assay | IC50=0.00511 μM | SANGER | ||
NOMO-1 | Growth Inhibition Assay | IC50=0.00513 μM | SANGER | ||
BV-173 | Growth Inhibition Assay | IC50=0.0053 μM | SANGER | ||
RO82-W-1 | Growth Inhibition Assay | IC50=0.00531 μM | SANGER | ||
LB2241-RCC | Growth Inhibition Assay | IC50=0.00531 μM | SANGER | ||
NCI-H2170 | Growth Inhibition Assay | IC50=0.00535 μM | SANGER | ||
SK-N-AS | Growth Inhibition Assay | IC50=0.00535 μM | SANGER | ||
NCI-H1651 | Growth Inhibition Assay | IC50=0.0054 μM | SANGER | ||
NCI-SNU-5 | Growth Inhibition Assay | IC50=0.00545 μM | SANGER | ||
SN12C | Growth Inhibition Assay | IC50=0.0055 μM | SANGER | ||
KY821 | Growth Inhibition Assay | IC50=0.00551 μM | SANGER | ||
SW1573 | Growth Inhibition Assay | IC50=0.00554 μM | SANGER | ||
OE19 | Growth Inhibition Assay | IC50=0.00559 μM | SANGER | ||
MPP-89 | Growth Inhibition Assay | IC50=0.00567 μM | SANGER | ||
HuCCT1 | Growth Inhibition Assay | IC50=0.00568 μM | SANGER | ||
SW1783 | Growth Inhibition Assay | IC50=0.0057 μM | SANGER | ||
8305C | Growth Inhibition Assay | IC50=0.00576 μM | SANGER | ||
OVCAR-4 | Growth Inhibition Assay | IC50=0.00586 μM | SANGER | ||
MMAC-SF | Growth Inhibition Assay | IC50=0.00586 μM | SANGER | ||
COLO-824 | Growth Inhibition Assay | IC50=0.0059 μM | SANGER | ||
HCC38 | Growth Inhibition Assay | IC50=0.006 μM | SANGER | ||
NCI-H1648 | Growth Inhibition Assay | IC50=0.00601 μM | SANGER | ||
NCI-H1573 | Growth Inhibition Assay | IC50=0.00607 μM | SANGER | ||
MFM-223 | Growth Inhibition Assay | IC50=0.00616 μM | SANGER | ||
NCI-H810 | Growth Inhibition Assay | IC50=0.00622 μM | SANGER | ||
EM-2 | Growth Inhibition Assay | IC50=0.00623 μM | SANGER | ||
D-283MED | Growth Inhibition Assay | IC50=0.00624 μM | SANGER | ||
NCI-H1755 | Growth Inhibition Assay | IC50=0.00624 μM | SANGER | ||
KYSE-70 | Growth Inhibition Assay | IC50=0.00624 μM | SANGER | ||
SW626 | Growth Inhibition Assay | IC50=0.00624 μM | SANGER | ||
WM-115 | Growth Inhibition Assay | IC50=0.00627 μM | SANGER | ||
NB69 | Growth Inhibition Assay | IC50=0.00629 μM | SANGER | ||
DOHH-2 | Growth Inhibition Assay | IC50=0.0063 μM | SANGER | ||
MEL-JUSO | Growth Inhibition Assay | IC50=0.00639 μM | SANGER | ||
IGR-1 | Growth Inhibition Assay | IC50=0.00641 μM | SANGER | ||
ACN | Growth Inhibition Assay | IC50=0.00644 μM | SANGER | ||
KARPAS-45 | Growth Inhibition Assay | IC50=0.00652 μM | SANGER | ||
HC-1 | Growth Inhibition Assay | IC50=0.00656 μM | SANGER | ||
MZ2-MEL | Growth Inhibition Assay | IC50=0.00658 μM | SANGER | ||
NCI-H1355 | Growth Inhibition Assay | IC50=0.00679 μM | SANGER | ||
HuP-T4 | Growth Inhibition Assay | IC50=0.00679 μM | SANGER | ||
AsPC-1 | Growth Inhibition Assay | IC50=0.00683 μM | SANGER | ||
SCC-15 | Growth Inhibition Assay | IC50=0.00689 μM | SANGER | ||
CP50-MEL-B | Growth Inhibition Assay | IC50=0.00693 μM | SANGER | ||
DMS-114 | Growth Inhibition Assay | IC50=0.00696 μM | SANGER | ||
KYSE-520 | Growth Inhibition Assay | IC50=0.007 μM | SANGER | ||
NCI-H2228 | Growth Inhibition Assay | IC50=0.00725 μM | SANGER | ||
COLO-829 | Growth Inhibition Assay | IC50=0.00725 μM | SANGER | ||
NCI-H2052 | Growth Inhibition Assay | IC50=0.00727 μM | SANGER | ||
HOP-92 | Growth Inhibition Assay | IC50=0.0073 μM | SANGER | ||
MDA-MB-231 | Growth Inhibition Assay | IC50=0.0073 μM | SANGER | ||
SK-MEL-30 | Growth Inhibition Assay | IC50=0.00732 μM | SANGER | ||
NCI-H2087 | Growth Inhibition Assay | IC50=0.00748 μM | SANGER | ||
SW900 | Growth Inhibition Assay | IC50=0.00755 μM | SANGER | ||
NCI-H358 | Growth Inhibition Assay | IC50=0.00758 μM | SANGER | ||
NCI-H2126 | Growth Inhibition Assay | IC50=0.00773 μM | SANGER | ||
TGBC24TKB | Growth Inhibition Assay | IC50=0.00781 μM | SANGER | ||
786-0 | Growth Inhibition Assay | IC50=0.00786 μM | SANGER | ||
no-10 | Growth Inhibition Assay | IC50=0.00788 μM | SANGER | ||
SCH | Growth Inhibition Assay | IC50=0.00818 μM | SANGER | ||
COLO-741 | Growth Inhibition Assay | IC50=0.0082 μM | SANGER | ||
NCI-H82 | Growth Inhibition Assay | IC50=0.00822 μM | SANGER | ||
MOLT-16 | Growth Inhibition Assay | IC50=0.00827 μM | SANGER | ||
IST-MES1 | Growth Inhibition Assay | IC50=0.0084 μM | SANGER | ||
NCI-H1623 | Growth Inhibition Assay | IC50=0.00856 μM | SANGER | ||
NCI-H1299 | Growth Inhibition Assay | IC50=0.00857 μM | SANGER | ||
SNU-423 | Growth Inhibition Assay | IC50=0.00857 μM | SANGER | ||
ALL-PO | Growth Inhibition Assay | IC50=0.0086 μM | SANGER | ||
DK-MG | Growth Inhibition Assay | IC50=0.0086 μM | SANGER | ||
LB1047-RCC | Growth Inhibition Assay | IC50=0.0088 μM | SANGER | ||
OMC-1 | Growth Inhibition Assay | IC50=0.00906 μM | SANGER | ||
TGBC1TKB | Growth Inhibition Assay | IC50=0.0091 μM | SANGER | ||
DBTRG-05MG | Growth Inhibition Assay | IC50=0.00917 μM | SANGER | ||
HPAF-II | Growth Inhibition Assay | IC50=0.00926 μM | SANGER | ||
A204 | Growth Inhibition Assay | IC50=0.00934 μM | SANGER | ||
TK10 | Growth Inhibition Assay | IC50=0.00977 μM | SANGER | ||
BHT-101 | Growth Inhibition Assay | IC50=0.0098 μM | SANGER | ||
SK-N-DZ | Growth Inhibition Assay | IC50=0.00983 μM | SANGER | ||
ChaGo-K-1 | Growth Inhibition Assay | IC50=0.00988 μM | SANGER | ||
NCI-H661 | Growth Inhibition Assay | IC50=0.01005 μM | SANGER | ||
AM-38 | Growth Inhibition Assay | IC50=0.01024 μM | SANGER | ||
ML-2 | Growth Inhibition Assay | IC50=0.01029 μM | SANGER | ||
TCCSUP | Growth Inhibition Assay | IC50=0.01036 μM | SANGER | ||
SW1990 | Growth Inhibition Assay | IC50=0.01047 μM | SANGER | ||
HCC1395 | Growth Inhibition Assay | IC50=0.01056 μM | SANGER | ||
PANC-10-05 | Growth Inhibition Assay | IC50=0.01056 μM | SANGER | ||
CAKI-1 | Growth Inhibition Assay | IC50=0.01073 μM | SANGER | ||
HuP-T3 | Growth Inhibition Assay | IC50=0.01077 μM | SANGER | ||
HT-1197 | Growth Inhibition Assay | IC50=0.01084 μM | SANGER | ||
MOLT-13 | Growth Inhibition Assay | IC50=0.01086 μM | SANGER | ||
NCI-H1563 | Growth Inhibition Assay | IC50=0.01087 μM | SANGER | ||
NCI-N87 | Growth Inhibition Assay | IC50=0.01093 μM | SANGER | ||
LB373-MEL-D | Growth Inhibition Assay | IC50=0.01094 μM | SANGER | ||
EFO-21 | Growth Inhibition Assay | IC50=0.011 μM | SANGER | ||
LU-134-A | Growth Inhibition Assay | IC50=0.01102 μM | SANGER | ||
DU-145 | Growth Inhibition Assay | IC50=0.01107 μM | SANGER | ||
SF295 | Growth Inhibition Assay | IC50=0.01126 μM | SANGER | ||
ABC-1 | Growth Inhibition Assay | IC50=0.01146 μM | SANGER | ||
TE-6 | Growth Inhibition Assay | IC50=0.01148 μM | SANGER | ||
GAK | Growth Inhibition Assay | IC50=0.01158 μM | SANGER | ||
LU-139 | Growth Inhibition Assay | IC50=0.01166 μM | SANGER | ||
EW-18 | Growth Inhibition Assay | IC50=0.01169 μM | SANGER | ||
MSTO-211H | Growth Inhibition Assay | IC50=0.01173 μM | SANGER | ||
KU812 | Growth Inhibition Assay | IC50=0.01198 μM | SANGER | ||
NCI-H441 | Growth Inhibition Assay | IC50=0.01198 μM | SANGER | ||
LU-99A | Growth Inhibition Assay | IC50=0.012 μM | SANGER | ||
NB10 | Growth Inhibition Assay | IC50=0.01209 μM | SANGER | ||
NCI-H1650 | Growth Inhibition Assay | IC50=0.01229 μM | SANGER | ||
YAPC | Growth Inhibition Assay | IC50=0.01237 μM | SANGER | ||
HT55 | Growth Inhibition Assay | IC50=0.01242 μM | SANGER | ||
NB7 | Growth Inhibition Assay | IC50=0.01243 μM | SANGER | ||
NCI-H2030 | Growth Inhibition Assay | IC50=0.01254 μM | SANGER | ||
EW-22 | Growth Inhibition Assay | IC50=0.01256 μM | SANGER | ||
UMC-11 | Growth Inhibition Assay | IC50=0.01283 μM | SANGER | ||
MKN7 | Growth Inhibition Assay | IC50=0.01283 μM | SANGER | ||
OE33 | Growth Inhibition Assay | IC50=0.013 μM | SANGER | ||
SK-LU-1 | Growth Inhibition Assay | IC50=0.01324 μM | SANGER | ||
LAMA-84 | Growth Inhibition Assay | IC50=0.01328 μM | SANGER | ||
IA-LM | Growth Inhibition Assay | IC50=0.0133 μM | SANGER | ||
HuH-7 | Growth Inhibition Assay | IC50=0.01354 μM | SANGER | ||
J82 | Growth Inhibition Assay | IC50=0.0139 μM | SANGER | ||
CFPAC-1 | Growth Inhibition Assay | IC50=0.01406 μM | SANGER | ||
MN-60 | Growth Inhibition Assay | IC50=0.01429 μM | SANGER | ||
A704 | Growth Inhibition Assay | IC50=0.01438 μM | SANGER | ||
SW684 | Growth Inhibition Assay | IC50=0.01452 μM | SANGER | ||
NOS-1 | Growth Inhibition Assay | IC50=0.0146 μM | SANGER | ||
U-118-MG | Growth Inhibition Assay | IC50=0.0147 μM | SANGER | ||
NCI-H596 | Growth Inhibition Assay | IC50=0.01477 μM | SANGER | ||
RS4-11 | Growth Inhibition Assay | IC50=0.01516 μM | SANGER | ||
KP-N-YS | Growth Inhibition Assay | IC50=0.01523 μM | SANGER | ||
MS-1 | Growth Inhibition Assay | IC50=0.01545 μM | SANGER | ||
A101D | Growth Inhibition Assay | IC50=0.01549 μM | SANGER | ||
DSH1 | Growth Inhibition Assay | IC50=0.016 μM | SANGER | ||
CAS-1 | Growth Inhibition Assay | IC50=0.01609 μM | SANGER | ||
NCI-H2347 | Growth Inhibition Assay | IC50=0.01636 μM | SANGER | ||
T-24 | Growth Inhibition Assay | IC50=0.01705 μM | SANGER | ||
MEG-01 | Growth Inhibition Assay | IC50=0.01737 μM | SANGER | ||
NCI-H2291 | Growth Inhibition Assay | IC50=0.01838 μM | SANGER | ||
SW872 | Growth Inhibition Assay | IC50=0.01867 μM | SANGER | ||
no-11 | Growth Inhibition Assay | IC50=0.01887 μM | SANGER | ||
NB5 | Growth Inhibition Assay | IC50=0.01891 μM | SANGER | ||
MZ7-mel | Growth Inhibition Assay | IC50=0.01934 μM | SANGER | ||
BT-474 | Growth Inhibition Assay | IC50=0.01943 μM | SANGER | ||
OAW-28 | Growth Inhibition Assay | IC50=0.01956 μM | SANGER | ||
ES6 | Growth Inhibition Assay | IC50=0.02008 μM | SANGER | ||
PC-3 | Growth Inhibition Assay | IC50=0.02036 μM | SANGER | ||
COR-L88 | Growth Inhibition Assay | IC50=0.02054 μM | SANGER | ||
D-392MG | Growth Inhibition Assay | IC50=0.02068 μM | SANGER | ||
LB2518-MEL | Growth Inhibition Assay | IC50=0.02161 μM | SANGER | ||
LoVo | Growth Inhibition Assay | IC50=0.02172 μM | SANGER | ||
HCC1954 | Growth Inhibition Assay | IC50=0.02192 μM | SANGER | ||
COLO-792 | Growth Inhibition Assay | IC50=0.02196 μM | SANGER | ||
KLE | Growth Inhibition Assay | IC50=0.02323 μM | SANGER | ||
MDA-MB-157 | Growth Inhibition Assay | IC50=0.02349 μM | SANGER | ||
PANC-08-13 | Growth Inhibition Assay | IC50=0.02465 μM | SANGER | ||
NCI-H727 | Growth Inhibition Assay | IC50=0.02474 μM | SANGER | ||
NCI-H1155 | Growth Inhibition Assay | IC50=0.02477 μM | SANGER | ||
GCIY | Growth Inhibition Assay | IC50=0.02502 μM | SANGER | ||
MKN1 | Growth Inhibition Assay | IC50=0.02576 μM | SANGER | ||
NCI-H1092 | Growth Inhibition Assay | IC50=0.02654 μM | SANGER | ||
RMG-I | Growth Inhibition Assay | IC50=0.027 μM | SANGER | ||
NB12 | Growth Inhibition Assay | IC50=0.0272 μM | SANGER | ||
RCM-1 | Growth Inhibition Assay | IC50=0.02819 μM | SANGER | ||
C3A | Growth Inhibition Assay | IC50=0.02822 μM | SANGER | ||
NCI-H747 | Growth Inhibition Assay | IC50=0.02837 μM | SANGER | ||
LB771-HNC | Growth Inhibition Assay | IC50=0.02837 μM | SANGER | ||
EW-13 | Growth Inhibition Assay | IC50=0.02904 μM | SANGER | ||
CAL-72 | Growth Inhibition Assay | IC50=0.02918 μM | SANGER | ||
HH | Growth Inhibition Assay | IC50=0.02998 μM | SANGER | ||
UACC-257 | Growth Inhibition Assay | IC50=0.0303 μM | SANGER | ||
OAW-42 | Growth Inhibition Assay | IC50=0.0303 μM | SANGER | ||
CAPAN-1 | Growth Inhibition Assay | IC50=0.03052 μM | SANGER | ||
SNU-C2B | Growth Inhibition Assay | IC50=0.03063 μM | SANGER | ||
NKM-1 | Growth Inhibition Assay | IC50=0.03169 μM | SANGER | ||
GR-ST | Growth Inhibition Assay | IC50=0.03185 μM | SANGER | ||
SW1463 | Growth Inhibition Assay | IC50=0.03337 μM | SANGER | ||
MEL-HO | Growth Inhibition Assay | IC50=0.03421 μM | SANGER | ||
NCI-H2342 | Growth Inhibition Assay | IC50=0.03633 μM | SANGER | ||
ACHN | Growth Inhibition Assay | IC50=0.0371 μM | SANGER | ||
RH-18 | Growth Inhibition Assay | IC50=0.03763 μM | SANGER | ||
HCC2218 | Growth Inhibition Assay | IC50=0.0379 μM | SANGER | ||
OS-RC-2 | Growth Inhibition Assay | IC50=0.03869 μM | SANGER | ||
KP-N-YN | Growth Inhibition Assay | IC50=0.03876 μM | SANGER | ||
COLO-668 | Growth Inhibition Assay | IC50=0.03887 μM | SANGER | ||
LU-65 | Growth Inhibition Assay | IC50=0.03904 μM | SANGER | ||
NB6 | Growth Inhibition Assay | IC50=0.03952 μM | SANGER | ||
HT | Growth Inhibition Assay | IC50=0.04007 μM | SANGER | ||
COLO-684 | Growth Inhibition Assay | IC50=0.04095 μM | SANGER | ||
NCI-H1693 | Growth Inhibition Assay | IC50=0.04305 μM | SANGER | ||
LAN-6 | Growth Inhibition Assay | IC50=0.04335 μM | SANGER | ||
MDA-MB-175-VII | Growth Inhibition Assay | IC50=0.04417 μM | SANGER | ||
KMOE-2 | Growth Inhibition Assay | IC50=0.04469 μM | SANGER | ||
DMS-79 | Growth Inhibition Assay | IC50=0.04579 μM | SANGER | ||
MHH-NB-11 | Growth Inhibition Assay | IC50=0.04614 μM | SANGER | ||
NCI-H69 | Growth Inhibition Assay | IC50=0.04849 μM | SANGER | ||
KE-37 | Growth Inhibition Assay | IC50=0.0501 μM | SANGER | ||
Ramos-2G6-4C10 | Growth Inhibition Assay | IC50=0.05067 μM | SANGER | ||
NCI-H1793 | Growth Inhibition Assay | IC50=0.05093 μM | SANGER | ||
HT-1376 | Growth Inhibition Assay | IC50=0.05186 μM | SANGER | ||
EKVX | Growth Inhibition Assay | IC50=0.05384 μM | SANGER | ||
Capan-2 | Growth Inhibition Assay | IC50=0.05396 μM | SANGER | ||
DoTc2-4510 | Growth Inhibition Assay | IC50=0.05446 μM | SANGER | ||
UACC-893 | Growth Inhibition Assay | IC50=0.05462 μM | SANGER | ||
SK-MEL-3 | Growth Inhibition Assay | IC50=0.05788 μM | SANGER | ||
SK-MEL-1 | Growth Inhibition Assay | IC50=0.058 μM | SANGER | ||
SW948 | Growth Inhibition Assay | IC50=0.05996 μM | SANGER | ||
P30-OHK | Growth Inhibition Assay | IC50=0.06167 μM | SANGER | ||
NH-12 | Growth Inhibition Assay | IC50=0.06244 μM | SANGER | ||
KU-19-19 | Growth Inhibition Assay | IC50=0.06361 μM | SANGER | ||
A431 | Growth Inhibition Assay | IC50=0.06374 μM | SANGER | ||
NCI-H2405 | Growth Inhibition Assay | IC50=0.06383 μM | SANGER | ||
KARPAS-299 | Growth Inhibition Assay | IC50=0.06582 μM | SANGER | ||
BALL-1 | Growth Inhibition Assay | IC50=0.06674 μM | SANGER | ||
KURAMOCHI | Growth Inhibition Assay | IC50=0.07073 μM | SANGER | ||
LS-1034 | Growth Inhibition Assay | IC50=0.07369 μM | SANGER | ||
MFE-280 | Growth Inhibition Assay | IC50=0.07536 μM | SANGER | ||
HOP-62 | Growth Inhibition Assay | IC50=0.07676 μM | SANGER | ||
KG-1 | Growth Inhibition Assay | IC50=0.07787 μM | SANGER | ||
CW-2 | Growth Inhibition Assay | IC50=0.07832 μM | SANGER | ||
SW837 | Growth Inhibition Assay | IC50=0.08342 μM | SANGER | ||
MFH-ino | Growth Inhibition Assay | IC50=0.08501 μM | SANGER | ||
HCC1419 | Growth Inhibition Assay | IC50=0.08987 μM | SANGER | ||
HMV-II | Growth Inhibition Assay | IC50=0.0901 μM | SANGER | ||
BEN | Growth Inhibition Assay | IC50=0.09385 μM | SANGER | ||
SK-N-FI | Growth Inhibition Assay | IC50=0.09556 μM | SANGER | ||
JVM-2 | Growth Inhibition Assay | IC50=0.09716 μM | SANGER | ||
CAL-54 | Growth Inhibition Assay | IC50=0.1004 μM | SANGER | ||
T84 | Growth Inhibition Assay | IC50=0.10952 μM | SANGER | ||
SHP-77 | Growth Inhibition Assay | IC50=0.11641 μM | SANGER | ||
G-361 | Growth Inhibition Assay | IC50=0.12324 μM | SANGER | ||
Calu-3 | Growth Inhibition Assay | IC50=0.13816 μM | SANGER | ||
HCC1937 | Growth Inhibition Assay | IC50=0.14937 μM | SANGER | ||
KM-H2 | Growth Inhibition Assay | IC50=0.1501 μM | SANGER | ||
769-P | Growth Inhibition Assay | IC50=0.15843 μM | SANGER | ||
NCI-H1304 | Growth Inhibition Assay | IC50=0.16061 μM | SANGER | ||
D-542MG | Growth Inhibition Assay | IC50=0.16278 μM | SANGER | ||
ATN-1 | Growth Inhibition Assay | IC50=0.17441 μM | SANGER | ||
NCI-H2029 | Growth Inhibition Assay | IC50=0.20243 μM | SANGER | ||
ZR-75-30 | Growth Inhibition Assay | IC50=0.20643 μM | SANGER | ||
SW1116 | Growth Inhibition Assay | IC50=0.21117 μM | SANGER | ||
CCRF-CEM | Growth Inhibition Assay | IC50=0.27614 μM | SANGER | ||
LU-135 | Growth Inhibition Assay | IC50=0.27739 μM | SANGER | ||
MC116 | Growth Inhibition Assay | IC50=0.28309 μM | SANGER | ||
LS-513 | Growth Inhibition Assay | IC50=0.28773 μM | SANGER | ||
NCI-H630 | Growth Inhibition Assay | IC50=0.29376 μM | SANGER | ||
L-428 | Growth Inhibition Assay | IC50=0.29883 μM | SANGER | ||
UM-UC-3 | Growth Inhibition Assay | IC50=0.31291 μM | SANGER | ||
NCI-H1838 | Growth Inhibition Assay | IC50=0.31784 μM | SANGER | ||
HEL | Growth Inhibition Assay | IC50=0.3224 μM | SANGER | ||
OCI-AML2 | Growth Inhibition Assay | IC50=0.32298 μM | SANGER | ||
A3-KAW | Growth Inhibition Assay | IC50=0.33477 μM | SANGER | ||
IGROV-1 | Growth Inhibition Assay | IC50=0.33755 μM | SANGER | ||
Mo-T | Growth Inhibition Assay | IC50=0.33853 μM | SANGER | ||
HDLM-2 | Growth Inhibition Assay | IC50=0.339 μM | SANGER | ||
HCC1569 | Growth Inhibition Assay | IC50=0.34309 μM | SANGER | ||
COLO-678 | Growth Inhibition Assay | IC50=0.37002 μM | SANGER | ||
COR-L105 | Growth Inhibition Assay | IC50=0.3793 μM | SANGER | ||
SK-MEL-24 | Growth Inhibition Assay | IC50=0.38382 μM | SANGER | ||
COLO-320-HSR | Growth Inhibition Assay | IC50=0.43976 μM | SANGER | ||
C8166 | Growth Inhibition Assay | IC50=0.49023 μM | SANGER | ||
COLO-679 | Growth Inhibition Assay | IC50=0.62172 μM | SANGER | ||
TE-12 | Growth Inhibition Assay | IC50=0.65394 μM | SANGER | ||
HAL-01 | Growth Inhibition Assay | IC50=0.6622 μM | SANGER | ||
H-EMC-SS | Growth Inhibition Assay | IC50=0.70546 μM | SANGER | ||
SNU-449 | Growth Inhibition Assay | IC50=0.72748 μM | SANGER | ||
C32 | Growth Inhibition Assay | IC50=0.74112 μM | SANGER | ||
K-562 | Growth Inhibition Assay | IC50=0.77024 μM | SANGER | ||
DJM-1 | Growth Inhibition Assay | IC50=0.78781 μM | SANGER | ||
RCC10RGB | Growth Inhibition Assay | IC50=0.79183 μM | SANGER | ||
CAL-85-1 | Growth Inhibition Assay | IC50=0.907 μM | SANGER | ||
NY | Growth Inhibition Assay | IC50=0.93352 μM | SANGER | ||
NCI-H1993 | Growth Inhibition Assay | IC50=1.19289 μM | SANGER | ||
SK-OV-3 | Growth Inhibition Assay | IC50=1.22089 μM | SANGER | ||
點擊查看更多細胞系數(shù)據(jù) |
產(chǎn)品描述 | Docetaxel多西他賽是一種taxol類似物,是一種microtubules解聚抑制劑,通過結(jié)合于穩(wěn)定的微管發(fā)揮作用。 | |
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靶點 |
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體外研究(In Vitro) | ||||
體外研究活性 | Docetaxel是一種細胞毒性劑,尤其對于增殖細胞,Docetaxel促進微管蛋白束的形成,還能誘導持續(xù)的有絲分裂阻滯,隨后分裂阻滯的細胞凋亡或永久抑制分裂。 Docetaxel抑制微管的動態(tài)不穩(wěn)定性及踏車現(xiàn)象,導致染色體不能分開到子細胞中,這樣又會反過來觸發(fā)有絲分裂過早結(jié)束,而不是在細胞周期的特定時期進行抑制作用。[2] Docetaxel (150 ng/mL) 處理人類小細胞肺癌 N417細胞系 1小時,抑制50% 細胞生長。 Docetaxel 處理 KB 人類表皮癌細胞, T24 人類膀胱癌細胞, Calc18 人類乳腺癌細胞, 和HCT116人類結(jié)腸腺癌96-120小時,IC50值分別為8 ng/mL, 4 ng/mL, 5 ng/mL, 和 7 ng/mL。[3] Docetaxel 處理人類癌細胞Hs746T (胃), AGS (胃), HeLa (子宮頸), CaSki (子宮頸), BxPC3 (胰腺), Capan-1 (胰腺) 24小時,抑制克隆存活,IC50 分別為 1 nM, 1 nM, 0.3 nM, 0.3 nM, 0.3 nM, 0.3 nM。[4] 通過克隆形成實驗測評Docetaxel處理人類 卵巢癌細胞系 OVCA432, A2780, A2780/cp8 12天期間,IC50值分別達到0.06 nM, 0.6 nM, 和3 nM。[5]Docetaxel 作用于9種培養(yǎng)的人類胃癌細胞系 (MKN-7, -28, -45, NUGC-4 和KATO-III, ST-SA-1, NAKAJIMA 和ST-KM, KKLS)時,IC50 分別為 >1.2 μM, 0.6 nM, 0.1 nM, 3.5 nM, 4 nM, 99 nM, 0.3 nM,0.5 nM, 0.9 nM。[6]在體外,Docetaxel在極低濃度時,抑制內(nèi)皮細胞遷移,這并不影響微管的大體形態(tài)或抑制細胞增殖,對微管動力學產(chǎn)生更微妙的影響。Docetaxel 抑制 HUVEC 遷移,IC50 為1 pM。Docetaxel 抑制血管生成因子胸甘磷酸化酶或血管內(nèi)皮生長因子刺激的HUVEC趨化性,IC 50 為10 pM 。[7] Docetaxel (30 μM) 在添加10%人血清的培養(yǎng)基中溫育12小時,誘導人單核細胞。[8] | |||
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細胞實驗 | 細胞系 | 人類胃癌細胞系 MKN-28 | ||
濃度 | 6 nM | |||
孵育時間 | 3 天 | |||
方法 | 180 μL培養(yǎng)基中的2000個細胞接種到96孔板中,20 μL 藥物溶液同時按一式三份加到每孔中。實驗板在37°C下含5% CO2的培養(yǎng)箱中溫育3天。在第3天,每孔加入25 μL MTT 試劑。溫育4小時后,除去培養(yǎng)基。每孔加入0.2 mL DMSO,使用機械式攪拌機充分混合,溶解形成的MTT-甲臜晶體。在540 nm (OD)處測定吸光值。 | |||
實驗圖片 | 檢測方法 | 檢測指標 | 實驗圖片 | PMID |
Western blot |
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