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Featured Products
Axon 2215
CAS [914471-09-3]
MF C9H7ClFN5O2MW 271.64
Potent competitive inhibitor of indoleamine 2,3-dioxygenase (IDO1, IC50 value 67 nM) with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model; This INCB024360-analog decreased kynurenine levels by >50% in plasma and inhibited B16-GM-CSF tumor growth in a dose dependent fashion.
INCB 024360 (or Epacadostat; Axon 1733) is available from Axon Medchem as well.
4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
[914471-09-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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