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Featured Products
Axon 2608
CAS [1622849-58-4]
MF C21H19N3O4MW 377.39
Potent inhibitor of Receptor-interacting serine/threonine-protein kinase 1 (RIPK1 or RIP1; IC50 value 2.8 nM for inhibition of S166 phosphorylation of hWT RIP1) exhibiting a remarkable specificity over >450 other kinases. GSK'481 protects against TNF-induced inflammation and lethal shock.
KEYWORDS: GSK481 | supplier | RIP1 kinase inhibitor | GSK'481 | CAS [1622849-58-4] | Phosphorylation | RIP | inflammation | TNF | RIPK1
(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)isoxazole-3-carboxamide
[1622849-58-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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