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EPZ 015666 - GSK 3235025

Based on 6 reference(s) in Google Scholar 8 10 6

Axon 2831

CAS [1616391-65-1]

MF C20H25N5O3
MW 383.44

  • Purity: 99%
  • Optical purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

EPZ 015666

Description

EPZ 015666 (GSK 3235025) is a potent, selective and orally available inhibitor of PRMT5 (IC50 value of 22 nM). EPZ 015666 exhibits antiproliferative effects in both in vitro and in vivo models of MCL.

KEYWORDS: EPZ015666 | supplier | PRMT5 inhibitor | GSK3235025 | EPZ-015666 | EPZ 015666 | GSK-3235025 | GSK 3235025 | CAS [1616391-65-1] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes

Potent, selective and orally available inhibitor of PRMT5

Chemical name

(S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide

Parent CAS No.

[1616391-65-1]

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10 mg $137.50 In Stock
50 mg $467.50 In Stock
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2 x 10 mg $220.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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