Wnt-C59 - C59
Axon 2287
CAS [1243243-89-1]
MF C25H21N3O
MW 379.45
- Purity: 98%
- Soluble in DMSO
Description
Nanomolar and orally available inhibitor of mammalian PORCN acyltransferase activity (IC50 value of 74 pM) that blocks activation of all evaluated human Wnts ( Wnt palmitoylation, Wnt interaction with the carrier protein Wntless/WLS, Wnt secretion, and Wnt activation of β-catenin reporter activity).The tumor growth inhibition of Wnt-C59 in MMTV-WNT1 transgenic mice is associated with decreased Wnt/β-catenin signaling in tumors.
Highly potent porcupine (Porcn) inhibitor
Chemical name
2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide
Parent CAS No.
[1243243-89-1]
Order
Size | Unit Price | Stock | |
---|---|---|---|
2 mg | $82.50 | In Stock | |
5 mg | $115.50 | In Stock | |
25 mg | $401.50 | In Stock |
Special Offers
Size | Unit Price | Stock | |
---|---|---|---|
2 x 5 mg | $176.00 | In Stock | |
2 x 25 mg | $594.00 | In Stock |
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