AZD6482 - KIN-193

Based on 21 reference(s) in Google Scholar 8 10 21

Axon 2926

CAS [1173900-33-8]

MF C22H24N4O4
MW 408.45

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

AZD6482

Description

AZD6482 is a potent and selective inhibitor of the p110β isoform of PI3K with an IC50 value of 0.69 nM. In addition, AZD6482 can inhibit the growth of tumors driven by p110β or PTEN-loss in vivo.

KEYWORDS: AZD6482 | supplier | PI3K p110β inhibitor | KIN-193 | AZD-6482 | AZD 6482 | KIN193 | KIN 193 | CAS [1173900-33-8] | Phosphatidylinositol | PI3K | Inhibitor | Enzymes | PTEN

J Ni et al. Functional characterization of an isoform-selective inhibitor of PI3K-p110ß as a potential anticancer agent. Cancer Discov. 2012 May;2(5):425-33.

Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153

PI3K inhibitor (p110 β specific)

Chemical name

(R)-2-(1-(7-Methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid

Parent CAS No.

[1173900-33-8]

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Size	Unit Price	Stock
5 mg	$132.00	In Stock
25 mg	$462.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	$198.00	In Stock

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AZD6482 - KIN-193

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Parent CAS No.

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AZD6482 - KIN-193

Description

Chemical name

Parent CAS No.

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