3-(Trifluoromethyl)phenylacetylene
Catalogue Number PC5947
Synonym(s):
3-(Trifluoromethyl)phenylacetylene is a fluorinated aromatic building block that is commonly used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of a tricyclic lead compound as a potent heparanse-1 inhibitor,[1] and in the synthesis of a prosta... Read More
- CAS Number
705-28-2
- Commodity Code
2902900000
- MDL Number
MFCD00467355
- Purity
- 98%
- Formula Weight
- 170.13 g/mol
- Density
- 1.178 g/cm3
- Boiling Point
- 146 °C
- Ref Index
- 1.464
- Flash Point
- 21 °C
- MSDS
- Typical Batch COA
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Product Description
3-(Trifluoromethyl)phenylacetylene is a fluorinated aromatic building block that is commonly used in the preparation of pharmaceutical and agrochemical components. It has been used in the synthesis of a tricyclic lead compound as a potent heparanse-1 inhibitor,[1] and in the synthesis of a prostaglandin EP4 receptor antagonist for treating autoimmune diseases and osteoarthritis.[2]
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1) https://www.sciencedirect.com/science/article/abs/pii/S0960894X22005261?via%3Dihub
2) https://worldwide.espacenet.com/patent/search/family/066631353/publication/EP3736276A1?q=pn%3DEP3736276