Product Description

Trimethylsilyl trifluoromethanesulphonate, also knows as Trimethylsilyl triflate or {[(Trifluoromethyl)sulphonyl]oxy}trimethylsilane, is an organosilicon.

In trifluoroacetic, it has been found to cleave, in the presence of thioanisole, a number of protecting groups currently employed in peptide synthesis, without significant side reactions and with a much faster rate of reaction than trifluoromethanesulphonic acid in trifluoroacetic acid. This new deprotecting reagent has been used in solution and solid phase peptide syntheses of nueromedin U-25 (a 25-residue peptide) and a rabit stomach peptide (an 8-residue peptide), respectively.

As one of the UK’s most established chemical distributors, we have a global reach. With over 25,000 compounds as potential precursors in stock, and with more than 3,000 diverse compounds created in our UK labs, you can trust Apollo to deliver the solution you need.

We have stock locations in both the UK and USA, so please get in touch if you would like to learn more about how to buy Trimethylsilyl trifluoromethanesulphonate.