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Anagrelide HCl

Catalog No.
A4352
Thrombocytopenic agent
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$61.00
In stock
10mg
$55.00
In stock
50mg
$187.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Anagrelide is a selective thrombocytopenic agent [1].

Anagrelide is a FDA-approved drug for the treatment of essential thrombocythemia. It is originally identified as a potential inhibitor of platelet aggregation. Anagrelide selectively affects thrombocytes while shows no significant effect on white blood cells, erythrocytes, or coagulation. Anagrelide is revealed to be available in 0.5mg capsules for oral administration.

Anagrelide is a potent inotropic agent for dogs with remarkable vasodilatory activity. Additionally, anagrelide can reduce renal blood flow. Furthermore, anagrelide has shown to play roles in other chronic myeloproliferative disorders, such as polycythemia vera, chronic myeloid leukemia and agnogenic myeloid metaplasia. Anagrelide has some side effects involving headache, diarrhea, edema, palpitations, and abdominal pain [1].

References:
[1] Oertel MD. Anagrelide, a selective thrombocytopenic agent. Am J Health Syst Pharm. 1998 Oct 1;55(19):1979-86.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt292.55
Cas No.58579-51-4
Formula C10H8Cl3N3O
Solubilityinsoluble in EtOH; insoluble in H2O; ≥4.9 mg/mL in DMSO
Chemical Name6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one;hydrochloride
SDFDownload SDF
Canonical SMILESC1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control