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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Pancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skeletal muscle relaxant. Pancuronium dibromide interrupts neuromuscular transmission by competing with acetylcholine for receptor sites on the motor end-plate. Pancuroni
Animal models
Rats
Dosage form
2 mg/kg, i.v.
Application
Two effects of pancuronium bromide on heart rate in vivo: A short-lasting injection effect, which may be due to an indirect sympathomimetic action, and a longer-lasting potentiation of cardiac sympathetic responses which is at least partly due to blockade of neuronal noradrenaline uptake.
Other notes
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.
References:
[1] Docherty JR, McGrath JC. Potentiation of cardiac sympathetic nerve responses in vivo by pancuronium bromide. Br J Pharmacol. 1977 Nov;61(3):472P-473P.
