Rifampin

Catalog No.

B2021

DNA-dependent RNA polymerase inhibitor

Grouped product items
Size	Price	Stock
10mM (in 1mL DMSO)	$61.00	In stock
1g	$55.00	In stock
5g	$209.00	In stock

For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Background

Rifampicin is a bactericidal antibiotic drug of the rifamycin group.

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	822.94
Cas No.	13292-46-1
Formula	C43H58N4O12
Solubility	≥26.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
SDF	Download SDF
Canonical SMILES	O[C@H]([C@H](C)[C@H]([C@H](/C=C/C=C(C)/C(NC1=C2O)=O)C)O)[C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O[C@@]3(C)OC4=C(C)C(O)=C2C(C(/C1=C/NN5CCN(C)CC5)=O)=C4C3=O)OC)OC(C)=O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Animal experiment:[1]
Animal models	Male Parkes strain mice (20 ~ 25g) inoculated in the left hind footpad with 1 × 10⁴ viable units of Mycobacterium marinum (M. marinum)
Dosage form	0.003%, 0.01%, 0.03% and 0.1% rifampin in the diet Administered by oral route
Applications	Rifampin at dosages of 0.003% and 0.01% in the diet was not suppressive to bacillary growth. A dosage of 0.03% resulted in a transient fall in viable bacillary count, which was followed by recovery of growth 10 days after inoculation. The highest dose (0.1%) was highly bactericidal, with the viable count of M. marinum reduced to, and maintained below, the detectable level of 2.0 × 10² organisms per foot pad after 7 days of treatment.
Note	The technical data provided above is for reference only.
	References: 1. Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy, 1976, 22(3-4): 242-252.

Purity = 97.35%