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MK-4827 tosylate

Catalog No.
B1164
PARP1/PARP2 inhibitor
Grouped product items
SizePriceStock Qty
2mg
$58.00
Ship with 10-15 days
5mg
$81.00
Ship with 10-15 days
10mg
$137.00
Ship with 10-15 days
50mg
$535.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt492.59
Cas No.1038915-73-9
FormulaC26H28N4O4S
SolubilitySoluble in DMSO
Chemical Name(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carbimidic acid compound with 4-methylbenzenesulfonic acid (1:1)
SDFDownload SDF
Canonical SMILESN=C(O)C1=CC=CC(C1=N2)=CN2C3=CC=C([C@]4([H])CCCNC4)C=C3.CC5=CC=C(S(O)(=O)=O)C=C5
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

MK-4827 tosylate