[ CAS No. 99-93-4 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

2D 3D

Structure of 99-93-4 * Storage: {[proInfo.prStorage]}

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	Inquiry	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price) ]}	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ item.pr_usastock ]}		{[ item.pr_chinastock ]}	{[ item.pr_remark ]}	Login		Inquiry

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

For Research Only 120K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 99-93-4 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 99-93-4 ]

SDS Specification

Alternatived Products of [ 99-93-4 ]

Product Citations

Synthesis of Alkylsilanes for Use as Molecular Diodes and Synthesis of Chemically Modified Alginate for Environmentally Sensitive Oral Drug Delivery

Morningstar, John Tanner ; Wake Forest University,2022.

Abstract: Molecular electronics is a continuously growing field which attempts to solve the problem that their solid-state counterparts encounter with continuing to grow smaller while maintaining the same functionality. Although successful molecular electronics have been created, their level of functionality does not yet match solid states. Furthering the field involves elucidating the mechanism of rectification and continuing to grow the library of compounds available. To accomplish this, we have successfully synthesized twenty new alkylsilanes which exhibit rectification behavior. We were able to draw several conclusions about promising scaffolds through examination of terminal groups with electron withdrawing and donating substituents, nitrogen heterocycles, and sterically hindered substituents. Additionally, our compounds were subjected to doping of the selfassembled monolayer devices which we found to benefit rectification. It was hypothesized that adding electron withdrawing groups, large and soft atoms, and groups with non-bonding electrons would also boost rectification. We obtained compounds with R ratios as high as 8500. This value is the highest our group has achieved to date. Biopolymers are commonly used as drug delivery scaffolds due to their safety and resistance to environmental stimuli. Alginate is one such polymer which has garnered increased attention as of late. To improve the properties of alginate for this purpose, we have developed a method to quantitatively modify the backbone of alginate with small molecules via sodium periodate oxidation and reductive amination of the corresponding oxidized product. Examining the difference in modified alginate with a small unsubstituted aromatic ring as well as an aromatic ketone, ester, and carboxylic acid allowed us to determine which molecules are beneficial to environmental pH sensitivity. xiv We successfully synthesized three new quantitatively modified alginates and examined their pH sensitivity using hydrogel beading studies. Each new compound shows distinct pH response; however, our expectations were met as our original benzoic acid modified product still holds the most desirable degradation profile.

Purchased from AmBeed: 89-71-4 ; 394-47-8 ; 3609-53-8 ; 100-68-5 ; 3112-85-4 ; 99-93-4

Product Details of [ 99-93-4 ]

CAS No. :	99-93-4	MDL No. :	MFCD00002359
Formula :	C₈H₈O₂	Boiling Point :	-
Linear Structure Formula :	HOC₆H₄C(O)CH₃	InChI Key :	TXFPEBPIARQUIG-UHFFFAOYSA-N
M.W :	136.15	Pubchem ID :	7469
Synonyms :	P-hydroxyacetophenone	Chemical Name :	4'-Hydroxyacetophenone

Calculated chemistry of [ 99-93-4 ] Expand+

Physicochemical Properties

Num. heavy atoms :	10
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.12
Num. rotatable bonds :	1
Num. H-bond acceptors :	2.0
Num. H-bond donors :	1.0
Molar Refractivity :	38.66
TPSA :	37.3 ?2

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	Yes
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.17 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.3
Log Po/w (XLOGP3) :	1.35
Log Po/w (WLOGP) :	1.59
Log Po/w (MLOGP) :	1.12
Log Po/w (SILICOS-IT) :	1.68
Consensus Log Po/w :	1.41

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-1.91
Solubility :	1.66 mg/ml ; 0.0122 mol/l
Class :	Very soluble
Log S (Ali) :	-1.74
Solubility :	2.5 mg/ml ; 0.0184 mol/l
Class :	Very soluble
Log S (SILICOS-IT) :	-2.13
Solubility :	1.02 mg/ml ; 0.00746 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.0

Safety of [ 99-93-4 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P280-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 99-93-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 99-93-4 ]
Downstream synthetic route of [ 99-93-4 ]

[ 99-93-4 ] Synthesis Path-Upstream 1~4

1
[ 99-93-4 ]
[ 23600-83-1 ]

Reference： [1] Journal of Organic Chemistry, 2003, vol. 68, # 25, p. 9563 - 9573

2
[ 7789-45-9 ]
[ 99-93-4 ]
[ 61791-99-9 ]

Reference： [1] Patent: EP2216052, 2010, A1,

3
[ 67-56-1 ]
[ 99-93-4 ]
[ 32136-81-5 ]

Reference： [1] European Journal of Organic Chemistry, 2016, vol. 2016, # 31, p. 5257 - 5262

4
[ 99-93-4 ]
[ 32136-81-5 ]

Reference： [1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 1, p. 191 - 194
[2] Helvetica Chimica Acta, 1994, vol. 77, p. 1595 - 1610

[ 99-93-4 ] Synthesis Path-Downstream 1~15

1
[ 102123-74-0 ]
[ 99-93-4 ]
[ 152438-66-9 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1993,vol. 41,p. 1079 - 1090

2
[ 2895-21-8 ]
[ 99-93-4 ]
N-isopropyl-(4-acetoxyphenyl)acetamide [ No CAS ]

Reference： [1]Journal of Chemical Research - Part S,1996,p. 424 - 425

3
[ 284462-56-2 ]
[ 32315-10-9 ]
[ 5369-19-7 ]
[ 350-46-9 ]
[ 99-93-4 ]
[ 75919-92-5 ]

Yield	Reaction Conditions	Operation in experiment
		Syntheses of Exemplified Compounds (see Tables for Compound Characterization) Entry 1: 4-(3-N-Methylcarbamoylphenoxy)aniline was prepared according to Method A13. According to Method C3, <strong>[5369-19-7]3-tert-butylaniline</strong> was reacted with bis(trichloromethyl)carbonate followed by 4-(3-N-Methylcarbamoylphenoxy)aniline to afford the urea. Entry 2: 4-Fluoro-1-nitrobenzene and p-hydroxyacetophenone were reacted according to Method A13, Step 1 to afford the 4-(4-acetylphenoxy)-1-nitrobenzene.
		Syntheses of Exemplified Compounds (See Tables for Compound Characterization) Entry 1: 4-(3-N-Methylcarbamoylphenoxy)aniline was prepared according to Method A13. According to Method C3, <strong>[5369-19-7]3-tert-butylaniline</strong> was reacted with bis(trichloromethyl)carbonate followed by 4-(3-N-Methylcarbamoylphenoxy)aniline to afford the urea. Entry 2: 4-Fluoro-1-nitrobenzene and p-hydroxyacetophenone were reacted according to Method A13, Step 1 to afford the 4-(4-acetylphenoxy)-1-nitrobenzene.
		SYNTHESES OF EXEMPLIFIED COMPOUNDS (See Tables for Compound Characterization) Entry 1: 4-(3-N-Methylcarbamoylphenoxy)aniline was prepared according to Method A13. According to Method C3, <strong>[5369-19-7]3-tert-butylaniline</strong> was reacted with bis(trichloromethyl)carbonate followed by 4-(3-N-Methylcarbamoylphenoxy)aniline to afford the urea. Entry 2: 4-Fluoro-1-nitrobenzene and p-hydroxyacetophenone were reacted according to Method A13, Step 1 to afford the 4-(4-acetylphenoxy)-1-nitrobenzene.

Reference： [1]Patent: US2003/144278,2003,A1
[2]Patent: US2001/11135,2001,A1
[3]Patent: US2002/165394,2002,A1

4
[ 1668-54-8 ]
[ 99-93-4 ]
[ 1465740-18-4 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,p. 5968 - 5970

5
[ 34800-90-3 ]
[ 99-93-4 ]
C₂₀H₁₈N₂O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
70.5%	In ethanol;Reflux;	General procedure: solutionof acid hydrazide (0.01 mol) and appropriate benzaldehyde/acetophenone (0.01 mol) in ethanol was refluxed for 5-6 h. The precipitated title compounds were then filtered off, washed with water and recrystallized from ethanol.

Reference： [1]Medicinal Chemistry,2013,vol. 9,p. 249 - 274

6
[ 92-55-7 ]
[ 99-93-4 ]
C₁₃H₉NO₅ [ No CAS ]

Reference： [1]Journal of Heterocyclic Chemistry,2015,vol. 52,p. 527 - 531

7
[ 92-55-7 ]
[ 99-93-4 ]
(3'R,4'R)-4'-(4-hydroxybenzoyl)-1'-methyl-3'-(5-nitro-2-furyl)spiro[indene-2,2'-pyrrolidine]-1,3-dione [ No CAS ]

Reference： [1]Journal of Heterocyclic Chemistry,2015,vol. 52,p. 527 - 531

8
[ 1120-95-2 ]
[ 99-93-4 ]
1-(4-(pyridazin-3-yloxy)phenyl)ethanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
13%	With potassium carbonate; In N,N-dimethyl-formamide; at 140℃; for 1h;Microwave irradiation;	A mixture of 1-(4-hydroxyphenyl)ethanone (283 mg, 2.08 mmol), <strong>[1120-95-2]3-<strong>[1120-95-2]chloropyridazine</strong></strong> (238 mg, 2.08 mmol) and potassium carbonate (574 mg, 4.16 mmol) in DMF (5 mL) is irradiated in a microwave reactor (Biotage Initiator) for 60 mm. at 140 oC. After cooling, the reaction mixture is filtered through Celite pad and the filter cake is washed with EtOAc. The filtrate and washings are washed with water and brine, dried over sodium sulfate, filtered and concentrated in vacuo. The residue is purified by column chromatography (Biotage) on silica gel (25 g) eluting with 10-80percent ethyl acetate in DCM to give the the titled compound (58 mg, 13percent yield) as a white solid.1HNMR (270 MHz, DMSO-d6): delta 9.07 (dd, J = 4.6, 1.3 Hz, 1H), 8.06 (d, J = 8.5 Hz, 2H), 7.84 (dd, J = 9.2, 4.6 Hz, 1H), 7.59-7.55 (m, 1H), 7.36 (d, J = 8.5 Hz, 2H), 2.60 (s, 3H).MS (ESI) mlz: 215.1 (M+H)÷.
13%	With potassium carbonate; In d7-N,N-dimethylformamide; at 140℃; for 1h;Microwave irradiation;	A mixture of i-(4-hydroxyphenyl)ethanone (283 mg, 2.08 mmol), <strong>[1120-95-2]3-<strong>[1120-95-2]chloropyridazine</strong></strong> (238 mg, 2.08 mmol) and potassium carbonate (574 mg, 4.16 mmol) in DMF (5 mL) was iffadiated in a microwave reactor (Biotage Initiator) for 60 mm. at 140°C. After cooling, the reaction mixture was filtered through Celite pad and the filtrate was washed with EtOAc. The filtrate was diluted with water and the organic layer was separated. After the extraction of the aqueous layer with EtOAc, the combined organic layers were washed with brine, dried over sodium sulfate, filtered and the filtrate was concentrated in vacuo. The residue was purified by column chromatography (Biotage) on silica gel (25 g) eluting with 10-80percent EtOAc in DCM to give the titled compound (58 mg, 13percent yield) as a white solid.1HNMR (270 MHz, DMSO-d6): delta 9.07 (dd, J = 4.6, 1.3 Hz, 1H), 8.06 (d, J = 8.5 Hz, 2H), 7.84 (dd, J = 9.2, 4.6 Hz, 1H), 7.59-7.55 (m, 1H), 7.36 (d, J = 8.5 Hz, 2H), 2.60 (s, 3H).

Reference： [1]Patent: WO2015/136947,2015,A1 .Location in patent: Paragraph 0242; 0243
[2]Patent: WO2017/43092,2017,A1 .Location in patent: Paragraph 0177; 0178

9
[ 1480-65-5 ]
[ 99-93-4 ]
C₁₃H₁₀ClNO₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; In N,N-dimethyl-formamide; at 100℃; for 6h;	General procedure for the synthesis of ClA mixture of 4?-hydroxyacetophenone (5.00 g, 36.7 mmol), <strong>[1480-65-5]5-chloro-2-fluoropyridine</strong> (5.79 g, 44.0 mmol) and K2C03 (10.1 g, 73.4 mmol) in DMF (150 mL) was stirred at 100 °C for 6 hours. After cooling to room temperature, the reaction mixture was diluted with EtOAc (200 mL), then filtered and the filtrate was washed with brine (150 mL x3), dried over anhydrous Na2SO4 and concentrated under reduced pressure to afford a residue. The residue was washed with PE/ EtOAc = 20/1(40 mL) to afford Cl.

Reference： [1]Patent: WO2016/16421,2016,A1 .Location in patent: Page/Page column 43

10
[ 186534-02-1 ]
[ 99-93-4 ]
(E)-1-(4-hydroxyphenyl)-3-(3,5,6-trimethylpyrazin-2-yl)prop-2-en-1-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
33.8%	With potassium hydroxide; In ethanol; for 10h;Cooling with ice;	Reaction step <strong>[186534-02-1]3,5,6-trimethylpyrazine-2-carbaldehyde</strong> (2.0 g, 13.3 mmol) was sequentially added to a 100 mL three-necked flask,4-hydroxyacetophenone (1.5 g, 11.0 mmol),Anhydrous ethanol 10mL,8.0 mL of a 20% KOH solution was slowly added dropwise under ice-cooling,Ice bath under the reaction 10h,TLC (petroleum ether - ethyl acetate 2: 1) detection reaction is almost complete,The reaction solution was poured into 100 mL of ice water,The pH was adjusted to 6-7 with 10% dilute hydrochloric acid,A yellow precipitate precipitated.filter,The filter cake was recrystallized from absolute ethanol,Dried to give 1.0 g of yellow crystals,The yield was 33.8%

Reference： [1]Patent: CN105237487,2016,A .Location in patent: Paragraph 0042; 0043; 0044; 0045

11
[ 28785-06-0 ]
[ 99-93-4 ]
1-(4-hydroxyphenyl)-3-(4-propylphenyl)propenone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
73%		General procedure: To the solution of (0.05 mol, 6.8 g) of 1-(4-Hydroxy-phenyl)-ethanone (1) in 30 ml of methanol on an ice bath, freshly prepared2 N methanolic NaOH solution (50 ml) was added and stirred for20 min. To this 0.05 mol of appropriate aldehyde (2a?l) was addedand the reaction mixture was stirred at room temperature for20?24 h. The reaction mixture was cooled in an ice bath andneutralized with dilute hydrochloric acid. The obtained precipitatewas separated by filtration and washed with distilled water to givethe crude product. The product (3a?o) so obtained was recrystallizedfrom 75percent methanol. The purity of the products was checkedon TLC by using a mixture of ethyl acetate and hexane as mobilephase.

Reference： [1]Bioorganic and Medicinal Chemistry,2017,vol. 25,p. 1949 - 1962

12
[ 28785-06-0 ]
[ 99-93-4 ]
[3-(4-hydroxyphenyl)-5-(4-propylphenyl)-4,5-dihydropyrazol-1-yl]pyridin-3-yl-methanone [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry,2017,vol. 25,p. 1949 - 1962

13
[ 4490-82-8 ]
[ 99-93-4 ]
(E)-1-(4-hydroxyphenyl)ethanone O-butyloxime [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
79%	In ethanol; at 20℃;	Hydroxylamine HCl (33 mg, 0.26 mmol) was added at room temperature to a solution of 4-hydroxyacetophenone (30 mg, 0.22 mmol) in EtOH (1 mL). The reaction mixture was stirred on TLC until all the starting material was consumed and quenched with H2O.The resulting mixture was diluted with EtOA and the organic phase was washed with H2O and brine, dried over MgSO4 and concentrated in vacuo.The residue was purified via flash column chromatography on silica gel (EtOAc: hexane = 1: 6 to 1: 5) to give a colorless liquid36 mg (79%) of Compound 14a

Reference： [1]Patent: KR2017/52873,2017,A .Location in patent: Paragraph 0141-0144

14
[ 41014-43-1 ]
[ 99-93-4 ]
1-(4-(benzo[d]oxazol-2-ylmethoxy)phenyl)ethanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
49.44%	With potassium carbonate; In acetone; for 4h;Reflux;	General procedure: To a solution of various substituted phenols (1 mmol) in dry acetone (30 mL) K2CO3 (1 mmol)and compound 3 or 4 (1 mmol) were added. After being stirred for 4 h at reflux temperature, thereaction mixture was cooled, filtered, and concentrated under vacuum. Then the residue was dilutedwith 30 mL ethyl acetate and sequentially washed with 30 mL 1 M HCl, aq. NaHCO3 solution andbrine in order. The organic layer was dried over MgSO4 and concentrated in vacuo. Purification of theresidue by chromatography on silica gel furnished target compounds. 1H-NMR, 13C-NMR and massspectroscopy (MS) of compounds 5a-m and 6a-m are shown in Supplementary Materials.

Reference： [1]Molecules,2018,vol. 23

15
[ 4903-09-7 ]
[ 99-93-4 ]
C₁₆H₁₃ClO₃ [ No CAS ]

Reference： [1]ChemMedChem,2018,vol. 13,p. 2208 - 2216

Recommend Products

Same Skeleton Products

Related Products

Isomers

Technical Information

? Acidity of Phenols ? Baeyer-Villiger Oxidation ? Barbier Coupling Reaction ? Baylis-Hillman Reaction ? Bucherer-Bergs Reaction ? Chan-Lam Coupling Reaction ? Clemmensen Reduction ? Corey-Bakshi-Shibata (CBS) Reduction ? Corey-Chaykovsky Reaction ? Electrophilic Substitution of the Phenol Aromatic Ring ? Etherification Reaction of Phenolic Hydroxyl Group ? Fischer Indole Synthesis ? Grignard Reaction ? Halogenation of Phenols ? Henry Nitroaldol Reaction ? Horner-Wadsworth-Emmons Reaction ? Hydride Reductions ? Lawesson's Reagent ? Leuckart-Wallach Reaction ? McMurry Coupling ? Meerwein-Ponndorf-Verley Reduction ? Oxidation of Phenols ? Passerini Reaction ? Paternò-Büchi Reaction ? Pechmann Coumarin Synthesis ? Petasis Reaction ? Peterson Olefination ? Pictet-Spengler Tetrahydroisoquinoline Synthesis ? Preparation of Aldehydes and Ketones ? Preparation of Amines ? Prins Reaction ? Reactions of Aldehydes and Ketones ? Reactions of Amines ? Reformatsky Reaction ? Reimer-Tiemann Reaction ? Robinson Annulation ? Schlosser Modification of the Wittig Reaction ? Schmidt Reaction ? Specialized Acylation Reagents-Ketenes ? Stobbe Condensation ? Tebbe Olefination ? Ugi Reaction ? Wittig Reaction ? Wolff-Kishner Reduction

Historical Records

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

[ CAS No. 99-93-4 ] {[proInfo.proName]}

Quality Control of [ 99-93-4 ]

Related Doc. of [ 99-93-4 ]

Product Citations

Product Details of [ 99-93-4 ]

Calculated chemistry of [ 99-93-4 ] Expand+

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 99-93-4 ]

Application In Synthesis of [ 99-93-4 ]

[ 99-93-4 ] Synthesis Path-Upstream 1~4

[ 99-93-4 ] Synthesis Path-Downstream 1~15

Technical Information

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry