成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 6451-86-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 6451-86-1
Chemical Structure| 6451-86-1
Structure of 6451-86-1 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 6451-86-1 ]

Related Doc. of [ 6451-86-1 ]

Alternatived Products of [ 6451-86-1 ]
Product Citations

Product Details of [ 6451-86-1 ]

CAS No. :6451-86-1 MDL No. :MFCD00666893
Formula : C15H13BrO3 Boiling Point : -
Linear Structure Formula :- InChI Key :RUBXMEDWBCBLEZ-UHFFFAOYSA-N
M.W : 321.17 Pubchem ID :10903319
Synonyms :

Calculated chemistry of [ 6451-86-1 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 19
Num. arom. heavy atoms : 12
Fraction Csp3 : 0.13
Num. rotatable bonds : 5
Num. H-bond acceptors : 3.0
Num. H-bond donors : 0.0
Molar Refractivity : 77.0
TPSA : 35.53 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : Yes
CYP2C9 inhibitor : Yes
CYP2D6 inhibitor : Yes
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.77 cm/s

Lipophilicity

Log Po/w (iLOGP) : 2.89
Log Po/w (XLOGP3) : 3.51
Log Po/w (WLOGP) : 3.7
Log Po/w (MLOGP) : 2.88
Log Po/w (SILICOS-IT) : 4.26
Consensus Log Po/w : 3.45

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -4.18
Solubility : 0.0212 mg/ml ; 0.0000661 mol/l
Class : Moderately soluble
Log S (Ali) : -3.94
Solubility : 0.0369 mg/ml ; 0.000115 mol/l
Class : Soluble
Log S (SILICOS-IT) : -5.97
Solubility : 0.000347 mg/ml ; 0.00000108 mol/l
Class : Moderately soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 2.27

Safety of [ 6451-86-1 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 6451-86-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6451-86-1 ]

[ 6451-86-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6451-86-1 ]
  • [ 133730-34-4 ]
  • [ 796843-31-7 ]
  • 2
  • [ 61439-59-6 ]
  • [ 6451-86-1 ]
  • [ 593-51-1 ]
  • [ 25895-60-7 ]
  • N-methyl-(4-benzyloxyphenethyl)-2-bromo-5-benzyloxy-4-methoxybenzylamine cyanoborohydride [ No CAS ]
YieldReaction ConditionsOperation in experiment
95.3% In 1,4-dioxane; acetic acid; at 20℃; 24 g to oxybenzylphenyl ethanol, 35 g 2 - bromo -5 - benzyloxy -4 - methoxy benzaldehyde and 10 g of methyl amine hydrochloride dispersed dissolved in 300 ml 1, 4 - dioxane, 30 g sodium dissolved in 10 ml acetic acid in, under the room temperature condition in the solution into the raw materials, the reaction at room temperature, HPLC monitoring reaction to the raw material of the basic reaction is complete, water quenching reaction, for 500 ml methylene chloride and 200 ml water extraction, in the organic phase, to obtain N - methyl - (4 - oxybenzylphenyl ethyl) -2 - bromo -5 - benzyloxy -4 - methoxybenzylamine cyano boron hydrogenated compound of the dichloromethane solution, measured by HPLC in this solution - N - methyl (4 - oxybenzylphenyl ethyl) -2 - bromo -5 - benzyloxy -4 - methoxybenzylamine cyano boron hydrogenated compound has a purity of 95.3percent.
Recommend Products
Same Skeleton Products

Technical Information

? Alkyl Halide Occurrence ? Barbier Coupling Reaction ? Baylis-Hillman Reaction ? Benzylic Oxidation ? Birch Reduction ? Blanc Chloromethylation ? Bucherer-Bergs Reaction ? Clemmensen Reduction ? Complex Metal Hydride Reductions ? Corey-Chaykovsky Reaction ? Corey-Fuchs Reaction ? Fischer Indole Synthesis ? Friedel-Crafts Reaction ? General Reactivity ? Grignard Reaction ? Hantzsch Dihydropyridine Synthesis ? Henry Nitroaldol Reaction ? Hiyama Cross-Coupling Reaction ? Horner-Wadsworth-Emmons Reaction ? Hydride Reductions ? Hydrogenolysis of Benzyl Ether ? Julia-Kocienski Olefination ? Kinetics of Alkyl Halides ? Knoevenagel Condensation ? Kumada Cross-Coupling Reaction ? Leuckart-Wallach Reaction ? McMurry Coupling ? Meerwein-Ponndorf-Verley Reduction ? Mukaiyama Aldol Reaction ? Nomenclature of Ethers ? Nozaki-Hiyama-Kishi Reaction ? Passerini Reaction ? Paternò-Büchi Reaction ? Petasis Reaction ? Pictet-Spengler Tetrahydroisoquinoline Synthesis ? Preparation of Aldehydes and Ketones ? Preparation of Alkylbenzene ? Preparation of Amines ? Preparation of Ethers ? Prins Reaction ? Reactions of Aldehydes and Ketones ? Reactions of Alkyl Halides with Reducing Metals ? Reactions of Amines ? Reactions of Benzene and Substituted Benzenes ? Reactions of Dihalides ? Reactions of Ethers ? Reformatsky Reaction ? Schlosser Modification of the Wittig Reaction ? Schmidt Reaction ? Stetter Reaction ? Stille Coupling ? Stobbe Condensation ? Substitution and Elimination Reactions of Alkyl Halides ? Suzuki Coupling ? Tebbe Olefination ? Ugi Reaction ? Vilsmeier-Haack Reaction ? Wittig Reaction ? Wolff-Kishner Reduction
Historical Records

Pharmaceutical Intermediates of
[ 6451-86-1 ]

Avoralstat Intermediates

Chemical Structure| 24207-22-5

[ 24207-22-5 ]

2-Bromo-3-methoxy-6-methylpyridine

Chemical Structure| 13682-77-4

[ 13682-77-4 ]

Potassium trifluoro(vinyl)borate

Chemical Structure| 23003-35-2

[ 23003-35-2 ]

2-Bromo-6-methylpyridin-3-ol

Chemical Structure| 1121-78-4

[ 1121-78-4 ]

5-Hydroxy-2-methylpyridine

Chemical Structure| 2973-59-3

[ 2973-59-3 ]

2-Bromo-5-hydroxy-4-methoxybenzaldehyde

Related Functional Groups of
[ 6451-86-1 ]

Aryls

Chemical Structure| 85604-06-4

[ 85604-06-4 ]

5-(Benzyloxy)-2-bromobenzaldehyde

Similarity: 0.95

Chemical Structure| 60632-40-8

[ 60632-40-8 ]

2-Bromo-4-hydroxy-5-methoxybenzaldehyde

Similarity: 0.93

Chemical Structure| 43192-32-1

[ 43192-32-1 ]

2-Bromo-5-ethoxybenzaldehyde

Similarity: 0.91

Chemical Structure| 162147-12-8

[ 162147-12-8 ]

2-Bromo-5-isopropoxybenzaldehyde

Similarity: 0.88

Chemical Structure| 7507-86-0

[ 7507-86-0 ]

2-Bromo-5-methoxybenzaldehyde

Similarity: 0.88

Bromides

Chemical Structure| 85604-06-4

[ 85604-06-4 ]

5-(Benzyloxy)-2-bromobenzaldehyde

Similarity: 0.95

Chemical Structure| 60632-40-8

[ 60632-40-8 ]

2-Bromo-4-hydroxy-5-methoxybenzaldehyde

Similarity: 0.93

Chemical Structure| 43192-32-1

[ 43192-32-1 ]

2-Bromo-5-ethoxybenzaldehyde

Similarity: 0.91

Chemical Structure| 162147-12-8

[ 162147-12-8 ]

2-Bromo-5-isopropoxybenzaldehyde

Similarity: 0.88

Chemical Structure| 7507-86-0

[ 7507-86-0 ]

2-Bromo-5-methoxybenzaldehyde

Similarity: 0.88

Aldehydes

Chemical Structure| 85604-06-4

[ 85604-06-4 ]

5-(Benzyloxy)-2-bromobenzaldehyde

Similarity: 0.95

Chemical Structure| 60632-40-8

[ 60632-40-8 ]

2-Bromo-4-hydroxy-5-methoxybenzaldehyde

Similarity: 0.93

Chemical Structure| 43192-32-1

[ 43192-32-1 ]

2-Bromo-5-ethoxybenzaldehyde

Similarity: 0.91

Chemical Structure| 162147-12-8

[ 162147-12-8 ]

2-Bromo-5-isopropoxybenzaldehyde

Similarity: 0.88

Chemical Structure| 7507-86-0

[ 7507-86-0 ]

2-Bromo-5-methoxybenzaldehyde

Similarity: 0.88

Ethers

Chemical Structure| 85604-06-4

[ 85604-06-4 ]

5-(Benzyloxy)-2-bromobenzaldehyde

Similarity: 0.95

Chemical Structure| 60632-40-8

[ 60632-40-8 ]

2-Bromo-4-hydroxy-5-methoxybenzaldehyde

Similarity: 0.93

Chemical Structure| 43192-32-1

[ 43192-32-1 ]

2-Bromo-5-ethoxybenzaldehyde

Similarity: 0.91

Chemical Structure| 162147-12-8

[ 162147-12-8 ]

2-Bromo-5-isopropoxybenzaldehyde

Similarity: 0.88

Chemical Structure| 7507-86-0

[ 7507-86-0 ]

2-Bromo-5-methoxybenzaldehyde

Similarity: 0.88

; ;