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CAS No. : | 63126-52-3 | MDL No. : | MFCD00077879 |
Formula : | C8H16N2O4 | Boiling Point : | No data available |
Linear Structure Formula : | - | InChI Key : | PCYDYHRBODKVEL-WDSKDSINSA-N |
M.W : | 204.22 | Pubchem ID : | 6999257 |
Synonyms : |
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Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
In dichloromethane; water; at 20℃; for 1.0h; | Example 26B; 2-Butyl-f 1.3.21dioxaborolane-(S.S)-4.5-dicarboxylic acid bis-dimethylamide; 2-(But-1-yl)-tetrahydro-4H-1,3,6,2-dioxazaborocine [CAS 92527-13-4] was prepared from n-butylboronic acid and 2-(2-hydroxy-ethylamino)-ethanol [CAS 111-42-2] as reported in Organic Synthesis, 1998, 76, 86-96. This dioxazaborocine (3 g, 17.5 mmol) and (2S,3S)-2,3-dihydroxy-N,N,N',N'- tetramethyl-butanediamide [CAS 63126-52-3] (4.65 g) were dissolved in anhydrous dichloromethane (95 ml.) under N2. Brine (30 ml_) was added. The resulting mixture was stirred at room temperature for 1 hour. The two layers were separated, and the aqueous layer was extracted with dichloromethane (30 ml_). The combined organic layers were washed with brine, dried over MgSO4, filtered and concentrated in vacuo to provide the title compound as an oil. 1H NMR (300 MHz, CDCI3): delta 0.82-0.9 (m, 5H), 1.25-1.45 (m, 4H), 2.98 (s, 6H), 3.2 (s, 6H), 5.52 (S, 2H). MS (DCI-NH3) m/z 271 (M+H)+. |