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[ CAS No. 622405-78-1 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
Chemical Structure| 622405-78-1
Chemical Structure| 622405-78-1
Structure of 622405-78-1 * Storage: {[proInfo.prStorage]}

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Quality Control of [ 622405-78-1 ]

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Product Details of [ 622405-78-1 ]

CAS No. :622405-78-1 MDL No. :MFCD11041112
Formula : C14H23NO8 Boiling Point : No data available
Linear Structure Formula :- InChI Key :MAYFFZZPEREGBQ-UHFFFAOYSA-N
M.W : 333.33 Pubchem ID :44622261
Synonyms :
Chemical Name :2,5-Dioxopyrrolidin-1-yl 2,5,8,11-tetraoxatetradecan-14-oate

Safety of [ 622405-78-1 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P305+P351+P338 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 622405-78-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 622405-78-1 ]

[ 622405-78-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 622405-78-1 ]
  • [ 1397-89-3 ]
  • C57H91NO22 [ No CAS ]
YieldReaction ConditionsOperation in experiment
In dimethyl sulfoxide; at 20℃; for 2h; AMB (Merck KGaA, Darmstadt, Germany) and MS(PEG)4 (MW: 333.3 Da, Thermo FisherScientific, Rockford, IL) were dissolved in anhydrous dimethylsulfoxide (DMSO) (Sigma-Aldrich, St. Louis, MO) to a concentration of 125 mM and 250 mM respectively. Differentmolar ratios of AMB toMS(PEG)4 were reacted in DMSO for 2 hours at room temperature,after which more DMSO was added to obtain an AMB concentration of 20 mM. The mixturewas then dispersed in a phosphate buffered saline solution with 3 mM EDTA at pH 8(PBS-EDTA) to a final concentration of 2 mM of AMB. To remove DMSO and unreactedMS(PEG)4 in the AMB-PEG formulation, concentration and diafiltration with PBS-EDTAwas performed using Amicon Ultra 0.5 mL 10 kDa centrifugal filters (Millipore, Billerica,MA), which retained AMB-PEG, at 4 C. Dynamic Light Scattering (DLS) analysis (describedbelow) was subsequently carried out on diafiltered and non-diafiltered samples, and it wasestablished that the diafiltration step did not significantly affect the particle size distributionof the AMB-PEG formulation. AMB-PEG formulations were then filtered using a 0.22 mumPVDF syringe filter (Millipore) prior to in vitro toxicity and activity tests.
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