成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 443-82-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 443-82-3
Chemical Structure| 443-82-3
Structure of 443-82-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 443-82-3 ]

Related Doc. of [ 443-82-3 ]

Alternatived Products of [ 443-82-3 ]
Product Citations

Product Details of [ 443-82-3 ]

CAS No. :443-82-3 MDL No. :MFCD00000323
Formula : C8H9F Boiling Point : -
Linear Structure Formula :- InChI Key :AWLDSXJCQWTJPC-UHFFFAOYSA-N
M.W : 124.16 Pubchem ID :96489
Synonyms :

Safety of [ 443-82-3 ]

Signal Word:Danger Class:3
Precautionary Statements:P210-P403+P235 UN#:1993
Hazard Statements:H225 Packing Group:Ⅲ
GHS Pictogram:

Application In Synthesis of [ 443-82-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 443-82-3 ]
  • Downstream synthetic route of [ 443-82-3 ]

[ 443-82-3 ] Synthesis Path-Upstream   1~8

  • 1
  • [ 87-59-2 ]
  • [ 443-82-3 ]
YieldReaction ConditionsOperation in experiment
63.4% With sodium nitrite In Et3N-3HF; diethyl ether EXAMPLE 5
Diazotization of 2,3-dimethylaniline in Et3N-3HF
2,3-Dimethylaniline (2.3 g, 0.02 mol) was syringed into Et3N-3HF (30 cm3) at 0° C.
The addition of sodium nitrite (2.0 g, 0.03 mol) caused the evolution of gas under the influence of ultrasound, which was significant during the first 25 minutes.
The clear reaction mixture gradually turned yellow and progressively darkened with the formation of tar.
The brown mixture was poured into water (150 cm3) and extracted with diethyl ether (180 cm3*2).
The remaining tarry residue was transferred to a Soxhlet apparatus and extracted repeatedly with diethyl ether (30 cm3) over 24 hours.
The ether extracts were dried over magnesium sulphate and fractional removal of diethyl ether afforded a brown oil.
Distillation of the oil at 142-143° C. at; atmospheric pressure afforded 1-fluoro-2,3-dimethylbenzene (1.47 g, 63.4percent) as a clear liquid.
The 1H n.m.r. spectrum had signals at δ&H (CDCl3) 2.18, 2-CH3 (d, J=2.0 Hz, 3H); 2.28, 3-CH3 (s, 3H); 6.88, 6-H (t, J=7.6 Hz, 1H) and 6.91, 4-H (d, J=7.6 Hz, 1H) and 7.03, 5-H (q, J=8.0 Hz and J=6.0 Hz, 1H).
The 19F n.m.r. spectrum had a signal at δF (CDCl3) 118.3, 1-F (tq, J=7.6 Hz and J=2.0 Hz).
The mass spectrum produced a molecular ion at m/z 124 and the expected fragmentation pattern for 1-fluoro-2,3-dimethylbenzene at m/z 109, 101, 96, 86, 83 and 77.
Reference： [1] Patent: US6179970, 2001, B2,
[2] Journal of the Chemical Society. Perkin Transactions 1, 2002, # 3, p. 402 - 415
[3] Proceedings - Indian Academy of Sciences, Section A, 1959, vol. <A> 50, p. 51,56, 58, 59
[4] Journal of Organic Chemistry, 1961, vol. 26, p. 3208 - 3211
  • 2
  • [ 36018-19-6 ]
  • [ 443-82-3 ]
Reference： [1] Journal of Organic Chemistry, 1998, vol. 63, # 8, p. 2493 - 2496
  • 3
  • [ 1412414-17-5 ]
  • [ 443-82-3 ]
YieldReaction ConditionsOperation in experiment
90 %Spectr. With lithium hydroxide monohydrate; silver trifluoromethanesulfonate; Selectfluor In ethyl acetate at 55℃; Sealed tube General procedure: Trifluoroborate (0.50 mmol, 1.0 equiv), LiOH·H2O (25.2 mg, 0.60 mmol, 1.2 equiv), Selectfluor? (212 mg, 0.60 mmol, 1.2 equiv), AgOTf (386 mg, 1.5 mmol, 3.0 equiv) were weighed into a 20 mL microwave vial. EtOAc (5 mL) was added, and sealed with a microwave cap and the mixture was allowed to stir at 55 °C for 5-15 h. The resulting solution was cooled to room temperature. For the compounds reported with isolated yields (2a, 2b, 2c, 2d, 2e, 2g, 2h, 2j, 2k, 2l, 2m, 2o, 2p, 2t, 2u, 2x, 2v, 2y, 2ab, 2ac, and 2ag) the reaction mixture was diluted with MTBE or hexane (5 mL) and H2O (4.0 mL). Then organic phase was separated, the aqueous phase was extracted with MTBE (2*5 mL). The combined organic phases were dried over anhydrous Na2SO4. The filtrate was concentrated in rotavapor and the residue was purified by column chromatography on Combiflash with hexanes/EtOAc to afford the desired compounds. The volatile and low yielding products were not isolated and their yields were determined only by 19F NMR of the reaction mixture. For the compounds reported with 19F NMR yields, 4-fluorobenzonitrile (0.50 mmol) was added as reference to the reaction mixture, stirred for 5 min, and then diluted with MTBE or hexane (5 mL) and H2O (3.0 mL).
The layers were separated and an an aliquote of the organic phase was withdrawn for the 19F NMR measurement in CDCl3.
Reference： [1] Tetrahedron, 2014, vol. 70, # 51, p. 9676 - 9681
  • 4
  • [ 62590-16-3 ]
  • [ 443-82-3 ]
  • [ 51736-79-9 ]
Reference： [1] Chemical Communications, 1997, # 13, p. 1163 - 1164
[2] Journal of the Chemical Society. Perkin Transactions 1, 2002, # 3, p. 402 - 415
  • 5
  • [ 95-47-6 ]
  • [ 452-64-2 ]
  • [ 62037-88-1 ]
  • [ 443-82-3 ]
Reference： [1] Journal of Organic Chemistry, 1991, vol. 56, # 26, p. 7347 - 7350
  • 6
  • [ 36018-19-6 ]
  • [ 120-82-1 ]
  • [ 443-82-3 ]
Reference： [1] Patent: US5874656, 1999, A,
  • 7
  • [ 95-47-6 ]
  • [ 452-64-2 ]
  • [ 443-82-3 ]
Reference： [1] Tetrahedron, 1993, vol. 49, # 36, p. 8129 - 8138
  • 8
  • [ 95-47-6 ]
  • [ 443-82-3 ]
Reference： [1] Journal of Organic Chemistry, 1978, vol. 43, # 5, p. 835 - 837
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 443-82-3 ]

Fluorinated Building Blocks

Chemical Structure| 452-67-5

[ 452-67-5 ]

2,5-Difluorotoluene

Similarity: 1.00

Chemical Structure| 443-88-9

[ 443-88-9 ]

2-Fluoro-1,3-dimethylbenzene

Similarity: 0.96

Chemical Structure| 452-76-6

[ 452-76-6 ]

2,4-Difluoro-1-methylbenzene

Similarity: 0.96

Chemical Structure| 696-01-5

[ 696-01-5 ]

2-Fluoro-1,4-dimethylbenzene

Similarity: 0.96

Chemical Structure| 443-84-5

[ 443-84-5 ]

2,6-Difluorotoluene

Similarity: 0.93

; ;