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[ CAS No. 4235-95-4 ] {[proInfo.proName]}

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Chemical Structure| 4235-95-4
Chemical Structure| 4235-95-4
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Product Citations

Product Citations

Conthagamage, Udyogi NK ; Rajeshwar T, Rajitha ; van der Ham, Stijn , et al. DOI: PubMed ID:

Abstract: Rotaxanes equipped with actuators hold great potential for developing highly functional molecular machines. Such systems could significantly enhance our ability to study and manipulate biological and artificial membranes. Here, we introduce a rotaxane with a ring featuring two azobenzene photoswitches, which retain their photoreversibility and can be stochastically shuttled along the axle in solution. Studies in model bilayers, supported by molecular dynamics simulations, show how azobenzene photoswitching alters the interaction of rotaxanes with surrounding lipids, leading to changes in lipid packing. Such changes in the lipid bilayer were leveraged to induce the light-triggered release of sulforhodamine B from large unilamellar vesicles. Additionally, light activation of the rotaxanes is shown to induce reversible contraction and expansion of giant unilamellar vesicles. The results provide novel insights into the interactions and operation of rotaxanes in lipid bilayers and their impact on membrane properties. This will aid in developing systems for precise membrane manipulation for applications in biomedicine and bioengineering.

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Product Details of [ 4235-95-4 ]

CAS No. :4235-95-4 MDL No. :MFCD00135191
Formula : C44H84NO8P Boiling Point : -
Linear Structure Formula :C36H68NPO8(CH2)8 InChI Key :SNKAWJBJQDLSFF-NVKMUCNASA-N
M.W : 786.11 Pubchem ID :10350317
Synonyms :
DOPC;sn-3-Dioleoyllecithin;PC(18:1(9Z)/18:1(9Z));18:1 (Δ9-Cis) PC;PDD 111;1,2-DOPC;1,2-Dioleoyl-sn-glycero-3-PC
Chemical Name :(R)-2,3-Bis(oleoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

Safety of [ 4235-95-4 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 4235-95-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4235-95-4 ]

[ 4235-95-4 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 4235-95-4 ]
  • [ 61-73-4 ]
  • C44H84NO8P*C34H24N6O14S4(4-)*4Na(1+) [ No CAS ]
  • 2
  • [ 57-09-0 ]
  • [ 4235-95-4 ]
  • [ 61-73-4 ]
  • 2C19H42N(1+)*2Br(1-)*C34H24N6O14S4(4-)*4Na(1+)*2C44H84NO8P [ No CAS ]
  • 3
  • [ 57-09-0 ]
  • [ 4235-95-4 ]
  • [ 61-73-4 ]
  • C19H42N(1+)*Br(1-)*C44H84NO8P*C34H24N6O14S4(4-)*4Na(1+) [ No CAS ]
  • 4
  • [ 57-09-0 ]
  • [ 4235-95-4 ]
  • [ 61-73-4 ]
  • 3C19H42N(1+)*3Br(1-)*3C44H84NO8P*C34H24N6O14S4(4-)*4Na(1+) [ No CAS ]
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