成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 3336-41-2 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 3336-41-2
Chemical Structure| 3336-41-2
Structure of 3336-41-2 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 3336-41-2 ]

Related Doc. of [ 3336-41-2 ]

Alternatived Products of [ 3336-41-2 ]
Product Citations

Product Details of [ 3336-41-2 ]

CAS No. :3336-41-2 MDL No. :MFCD00002550
Formula : C7H4Cl2O3 Boiling Point : -
Linear Structure Formula :- InChI Key :AULKDLUOQCUNOK-UHFFFAOYSA-N
M.W : 207.01 Pubchem ID :18749
Synonyms :

Calculated chemistry of [ 3336-41-2 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 12
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.0
Num. rotatable bonds : 1
Num. H-bond acceptors : 3.0
Num. H-bond donors : 2.0
Molar Refractivity : 45.44
TPSA : 57.53 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.72 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.31
Log Po/w (XLOGP3) : 2.59
Log Po/w (WLOGP) : 2.4
Log Po/w (MLOGP) : 2.17
Log Po/w (SILICOS-IT) : 2.04
Consensus Log Po/w : 2.1

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.56

Water Solubility

Log S (ESOL) : -3.06
Solubility : 0.181 mg/ml ; 0.000873 mol/l
Class : Soluble
Log S (Ali) : -3.45
Solubility : 0.074 mg/ml ; 0.000357 mol/l
Class : Soluble
Log S (SILICOS-IT) : -2.43
Solubility : 0.762 mg/ml ; 0.00368 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.33

Safety of [ 3336-41-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 3336-41-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3336-41-2 ]

[ 3336-41-2 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 91-22-5 ]
  • [ 3336-41-2 ]
  • [ 87-65-0 ]
  • 2
  • [ 67-56-1 ]
  • [ 3336-41-2 ]
  • [ 3337-59-5 ]
YieldReaction ConditionsOperation in experiment
84.9% With toluene-4-sulfonic acid; for 6h;Reflux; [0246] 62.1 g (0.30 mol) of <strong>[3336-41-2]4-hydroxy-3,5-dichlorobenzoic acid</strong> was dissolved in 300 mL of methanol. 3 g of p-toluenesulfonic acid was added. The reaction mixture was heated and refluxed for 6 hours. The solvent was removed under reduced pressure. The residue was dissolved in 500 mL of dichloromethane, washed with water three times (200 mL3), and dried over anhydrous magnesium sulfate. The desiccant was removed by filtration, and the solvent was removed to obtain 56.3 g of the target product with a yield of 84.9%. m/z 219.01(M-H).
  • 3
  • [ 628-17-1 ]
  • [ 3336-41-2 ]
  • 3,5-dichloro-4-pentyloxy-benzoic acid [ No CAS ]
  • 7
  • [ 3336-41-2 ]
  • 4-ethoxymethyl-2,6-dichloro-phenol [ No CAS ]
  • 9
  • [ 163205-74-1 ]
  • [ 3336-41-2 ]
  • 11
  • [ 99-96-7 ]
  • [ 3336-41-2 ]
YieldReaction ConditionsOperation in experiment
63.5% With hydrogenchloride; dihydrogen peroxide; In water; 10 mLof 33percent hydrogen peroxide was added to a suspension of 3.5 g (0.025 mol) of 4-hydroxybenzoic acid I in10 mL of hydrochloric acid and 20 mL of water. The formed white precipitate was filtered off, washed with hot water, and recrystallized from ethanol. Yield 3.19 g (63.5percent), white crystals, mp 265°C. 1H NMR spectrum, , ppm: 7.84 s (2H, H2,6). Found, percent: C40.64; H 1.87; Cl 34.34. C7H4Cl2O2. Calculated, percent: C40.58; H 1.93; Cl 34.30.
  • 12
  • [ 3336-41-2 ]
  • [ 112-82-3 ]
  • [ 59100-50-4 ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 3336-41-2 ]

Aryls

Chemical Structure| 3337-59-5

[ 3337-59-5 ]

Methyl 3,5-dichloro-4-hydroxybenzoate

Similarity: 0.93

Chemical Structure| 3964-58-7

[ 3964-58-7 ]

3-Chloro-4-hydroxybenzoic acid

Similarity: 0.93

Chemical Structure| 320-72-9

[ 320-72-9 ]

3,5-Dichloro-2-hydroxybenzoic acid

Similarity: 0.92

Chemical Structure| 37908-97-7

[ 37908-97-7 ]

3,5-Dichloro-4-methoxybenzoic acid

Similarity: 0.90

Chemical Structure| 1829-32-9

[ 1829-32-9 ]

3-Chloro-2-hydroxybenzoic acid

Similarity: 0.90

Chlorides

Chemical Structure| 3337-59-5

[ 3337-59-5 ]

Methyl 3,5-dichloro-4-hydroxybenzoate

Similarity: 0.93

Chemical Structure| 3964-58-7

[ 3964-58-7 ]

3-Chloro-4-hydroxybenzoic acid

Similarity: 0.93

Chemical Structure| 320-72-9

[ 320-72-9 ]

3,5-Dichloro-2-hydroxybenzoic acid

Similarity: 0.92

Chemical Structure| 37908-97-7

[ 37908-97-7 ]

3,5-Dichloro-4-methoxybenzoic acid

Similarity: 0.90

Chemical Structure| 1829-32-9

[ 1829-32-9 ]

3-Chloro-2-hydroxybenzoic acid

Similarity: 0.90

Carboxylic Acids

Chemical Structure| 3964-58-7

[ 3964-58-7 ]

3-Chloro-4-hydroxybenzoic acid

Similarity: 0.93

Chemical Structure| 320-72-9

[ 320-72-9 ]

3,5-Dichloro-2-hydroxybenzoic acid

Similarity: 0.92

Chemical Structure| 37908-97-7

[ 37908-97-7 ]

3,5-Dichloro-4-methoxybenzoic acid

Similarity: 0.90

Chemical Structure| 1829-32-9

[ 1829-32-9 ]

3-Chloro-2-hydroxybenzoic acid

Similarity: 0.90

Chemical Structure| 34113-69-4

[ 34113-69-4 ]

4-Chloro-3-hydroxybenzoic acid

Similarity: 0.89

; ;