成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 23235-01-0 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 23235-01-0
Chemical Structure| 23235-01-0
Structure of 23235-01-0 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 23235-01-0 ]

Related Doc. of [ 23235-01-0 ]

Alternatived Products of [ 23235-01-0 ]
Product Citations

Product Details of [ 23235-01-0 ]

CAS No. :23235-01-0 MDL No. :
Formula : C5H7NO2 Boiling Point : -
Linear Structure Formula :HCCCH2CH(NH2)COOH InChI Key :-
M.W : 113.11 Pubchem ID :-
Synonyms :
Chemical Name :(S)-2-Aminopent-4-ynoic acid

Calculated chemistry of [ 23235-01-0 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 8
Num. arom. heavy atoms : 0
Fraction Csp3 : 0.4
Num. rotatable bonds : 2
Num. H-bond acceptors : 3.0
Num. H-bond donors : 2.0
Molar Refractivity : 28.79
TPSA : 63.32 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -8.27 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.86
Log Po/w (XLOGP3) : -1.8
Log Po/w (WLOGP) : -0.5
Log Po/w (MLOGP) : -2.31
Log Po/w (SILICOS-IT) : -0.54
Consensus Log Po/w : -0.86

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : 0.72
Solubility : 600.0 mg/ml ; 5.31 mol/l
Class : Highly soluble
Log S (Ali) : 0.99
Solubility : 1100.0 mg/ml ; 9.7 mol/l
Class : Highly soluble
Log S (SILICOS-IT) : 0.63
Solubility : 480.0 mg/ml ; 4.25 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 2.21

Safety of [ 23235-01-0 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 23235-01-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 23235-01-0 ]

[ 23235-01-0 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 23235-01-0 ]
  • [ 102774-86-7 ]
  • [ 198561-07-8 ]
  • 2
  • [ 23235-01-0 ]
  • [ 82911-69-1 ]
  • [ 198561-07-8 ]
  • 3
  • [ 636-58-8 ]
  • [ 23235-01-0 ]
  • C13H19N3O6S [ No CAS ]
  • 4
  • [ 636-58-8 ]
  • [ 23235-01-0 ]
  • C35H32N4O12S [ No CAS ]
  • 5
  • [ 198561-07-8 ]
  • [ 23235-01-0 ]
YieldReaction ConditionsOperation in experiment
92% With piperidine; In N,N-dimethyl-formamide; at 20℃; for 0.5h; Fmoc-protected propargyl glycine (200mg) was dissolved in 20mL of piperidine/DMF solution (1:4). Reaction was stirred for 30min at room temperature. The volume was reduced by rotary evaporation and 25mL of cold ether was added to precipitate the amino acid. The suspended mixture was centrifuged at 4000rpm at 4C for 10min and washed twice with cold ether (10mL×2). The amino acid was loaded onto a C18 cartridge for flash purification (ACN/H2O). 1H NMR (D2O, 400MHz): delta 3.89 (t, 1H, J=5.4Hz), 2.87-2.81 (m, 2H,), 2.52 (t, 1H, J=2.6Hz). 13C NMR (D2O, 101MHz): delta 172.7, 77.5, 73.4, 52.8, 20.4.HRMS (ESI) calculated (M-H) 112.0404, found 112.0415.
Recommend Products
Same Skeleton Products
Historical Records

Related Functional Groups of
[ 23235-01-0 ]

Amino Acid Derivatives

Chemical Structure| 23235-03-2

[ 23235-03-2 ]

(R)-2-Aminopent-4-ynoic acid

Similarity: 1.00

Chemical Structure| 50428-03-0

[ 50428-03-0 ]

2-Aminopent-4-ynoic acid

Similarity: 1.00

Chemical Structure| 198774-27-5

[ 198774-27-5 ]

(S)-2-Aminopent-4-ynoic acid hydrochloride

Similarity: 0.97

Chemical Structure| 16900-57-5

[ 16900-57-5 ]

2-Aminopent-4-ynoic acid hydrochloride

Similarity: 0.97

Chemical Structure| 87205-47-8

[ 87205-47-8 ]

(R)-2-Aminopent-4-ynoic acid hydrochloride

Similarity: 0.97

; ;