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CAS No. : | 14648-57-8 | MDL No. : | MFCD01837553 |
Formula : | C12H20O | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | YUBKBLFRGDNIDR-UHFFFAOYSA-N |
M.W : | 180.29 | Pubchem ID : | 4401951 |
Synonyms : |
|
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P280-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
2.31 parts of the salt represented by formula (I-1-a) and 20 parts of acetonitrile are mixed,The mixture was stirred at 23 C for 30 minutes.1.80 parts of carbonyldiimidazole was added to the obtained mixed solution,The mixture was stirred at 60 C for 2 hours.2.17 parts of the compound represented by the formula (I-27-b) was added to the obtained reaction solution, and the mixture was stirred at 60 C. for 2 hours and then cooled to 23 C. Chloroform (40 parts) and ion-exchanged water (20 parts) were added to the obtained reaction mixture, and the mixture was stirred at 23 C. for 30 minutes, then, separated, and the organic layer was taken out. 20 parts of ion-exchanged water was added to the obtained organic layer, the mixture was stirred at 23 C. for 30 minutes, and then liquid-separated to take out the organic layer. This water washing operation was repeated 5 times. The obtained organic layer was concentrated, and the concentrated mixture was applied to a column (silica gel 60N (spherical, neutral) 100-210 μm; manufactured by Kanto Chemical Co., Inc., developing solvent: n-heptane / ethyl acetate = 1/1). By fractionating, 2.18 parts of a compound represented by the formula (I-27-c) was obtained. |
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