成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 1361227-58-8 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1361227-58-8
Chemical Structure| 1361227-58-8
Structure of 1361227-58-8 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 1361227-58-8 ]

Related Doc. of [ 1361227-58-8 ]

Alternatived Products of [ 1361227-58-8 ]
Product Citations

Product Details of [ 1361227-58-8 ]

CAS No. :1361227-58-8 MDL No. :MFCD28137969
Formula : C25H15Br Boiling Point : -
Linear Structure Formula :- InChI Key :UIUSRIQSFHZPSQ-UHFFFAOYSA-N
M.W : 395.29 Pubchem ID :21032472
Synonyms :

Calculated chemistry of [ 1361227-58-8 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 26
Num. arom. heavy atoms : 24
Fraction Csp3 : 0.04
Num. rotatable bonds : 0
Num. H-bond acceptors : 0.0
Num. H-bond donors : 0.0
Molar Refractivity : 110.44
TPSA : 0.0 ?2

Pharmacokinetics

GI absorption : Low
BBB permeant : No
P-gp substrate : Yes
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : Yes
CYP2C9 inhibitor : Yes
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -3.69 cm/s

Lipophilicity

Log Po/w (iLOGP) : 3.88
Log Po/w (XLOGP3) : 7.07
Log Po/w (WLOGP) : 6.79
Log Po/w (MLOGP) : 6.66
Log Po/w (SILICOS-IT) : 7.24
Consensus Log Po/w : 6.33

Druglikeness

Lipinski : 1.0
Ghose : None
Veber : 0.0
Egan : 1.0
Muegge : 2.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -7.43
Solubility : 0.0000148 mg/ml ; 0.0000000373 mol/l
Class : Poorly soluble
Log S (Ali) : -6.89
Solubility : 0.0000512 mg/ml ; 0.000000129 mol/l
Class : Poorly soluble
Log S (SILICOS-IT) : -10.98
Solubility : 0.0000000042 mg/ml ; 0.0 mol/l
Class : Insoluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 2.0
Synthetic accessibility : 3.84

Safety of [ 1361227-58-8 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P280-P305+P351+P338 UN#:N/A
Hazard Statements:H302 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1361227-58-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1361227-58-8 ]

[ 1361227-58-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 654664-63-8 ]
  • [ 1361227-58-8 ]
  • C43H26 [ No CAS ]
YieldReaction ConditionsOperation in experiment
94% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water; for 30h;Schlenk technique; The structural formula and synthesis route of compound 1-112 are shown in the following formula:In a 200mL Schlenk bottle,3-bromo-9,9'-spirobifluorene 3.95 g (10.00 mmol) was added,2-Bactofurazine borate 2.72 g (10.00 mmol),Tetrakis(triphenylphosphine) palladium 0.26 g (0.23 mmol),Anhydrous potassium carbonate 2.76g (20.0mmol),Tetrahydrofuran 50mL,Water 8mL,Under argon gas protection,The reaction was stirred at 70C for 30 hours.The reaction is complete.Evaporate the solvent,With 50mL twoChloroform and 50mL of water dissolve the residue,Washed,Separate the organic layer,The aqueous layer was extracted twice with 15 mL of dichloromethane.Combine organic layers,Wash twice with neutral to 50mLAfter the solvent is evaporated,The residue was separated by column chromatography (350 mesh silica gel,The eluent is petroleum ether:Chloroform = 2.5:1 (V/V),The solvent was distilled off and after drying, 5.11 g of white crystals were obtained with a yield of 94%.MS(EI): m/z 542.21 [M+].Elemental Analysis Calculated Value for C43H26 (%): C 95.17, H 4.83; Found: 95.19, H4.80.
  • 2
  • [ 1036378-83-2 ]
  • [ 1361227-58-8 ]
  • 3-triphenyl-9,9'-spirobifluorene [ No CAS ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records
; ;