成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 13534-89-9 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 13534-89-9
Chemical Structure| 13534-89-9
Structure of 13534-89-9 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 13534-89-9 ]

Related Doc. of [ 13534-89-9 ]

Alternatived Products of [ 13534-89-9 ]
Product Citations

Product Details of [ 13534-89-9 ]

CAS No. :13534-89-9 MDL No. :MFCD00234014
Formula : C5H3Br2N Boiling Point : No data available
Linear Structure Formula :- InChI Key :SLMHHOVQRSSRCV-UHFFFAOYSA-N
M.W : 236.89 Pubchem ID :817102
Synonyms :

Calculated chemistry of [ 13534-89-9 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 8
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.0
Num. rotatable bonds : 0
Num. H-bond acceptors : 1.0
Num. H-bond donors : 0.0
Molar Refractivity : 39.64
TPSA : 12.89 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.92 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.96
Log Po/w (XLOGP3) : 2.57
Log Po/w (WLOGP) : 2.61
Log Po/w (MLOGP) : 2.01
Log Po/w (SILICOS-IT) : 2.8
Consensus Log Po/w : 2.39

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -3.48
Solubility : 0.0779 mg/ml ; 0.000329 mol/l
Class : Soluble
Log S (Ali) : -2.49
Solubility : 0.769 mg/ml ; 0.00325 mol/l
Class : Soluble
Log S (SILICOS-IT) : -3.74
Solubility : 0.0435 mg/ml ; 0.000184 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.69

Safety of [ 13534-89-9 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P305+P351+P338 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 13534-89-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13534-89-9 ]

[ 13534-89-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 13534-89-9 ]
  • [ 452972-08-6 ]
  • 2
  • [ 13534-89-9 ]
  • [ 25475-67-6 ]
  • N-(3-bromopyridin-2-yl)isoquinolin-3-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
80% With tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; In 1,4-dioxane; for 10h;Inert atmosphere; General procedure: A round-bottomed flask was charged with Pd2(dba)3 (5 mol percent ), ligand (10 molpercent), aryl halide (1mmol), appropriate isoquinolinamine (1 mmol), base (1.5 mmol) and dry solvent (5 mL). Theflask was flushed with argon for 5 min. The mixture was heated at reflux under magnetic stirring.After cooling down to room temperature, the reaction mixture was concentrated and the residuewas purified by flash column chromatography on silica gel.
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 13534-89-9 ]

Bromides

Chemical Structure| 53242-19-6

[ 53242-19-6 ]

5,6-Dibromopyridin-3-amine

Similarity: 0.88

Chemical Structure| 89284-11-7

[ 89284-11-7 ]

5,6-Dibromopyridin-2-amine

Similarity: 0.83

Chemical Structure| 58530-53-3

[ 58530-53-3 ]

2,4-Dibromopyridine

Similarity: 0.79

Chemical Structure| 109-04-6

[ 109-04-6 ]

2-Bromopyridine

Similarity: 0.76

Chemical Structure| 626-05-1

[ 626-05-1 ]

2,6-Dibromopyridine

Similarity: 0.74

Related Parent Nucleus of
[ 13534-89-9 ]

Pyridines

Chemical Structure| 53242-19-6

[ 53242-19-6 ]

5,6-Dibromopyridin-3-amine

Similarity: 0.88

Chemical Structure| 89284-11-7

[ 89284-11-7 ]

5,6-Dibromopyridin-2-amine

Similarity: 0.83

Chemical Structure| 58530-53-3

[ 58530-53-3 ]

2,4-Dibromopyridine

Similarity: 0.79

Chemical Structure| 109-04-6

[ 109-04-6 ]

2-Bromopyridine

Similarity: 0.76

Chemical Structure| 626-05-1

[ 626-05-1 ]

2,6-Dibromopyridine

Similarity: 0.74

; ;