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CAS No. : | 1309666-78-1 | MDL No. : | MFCD22201525 |
Formula : | C16H24O6S | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | OVLSSENVXOKYAD-UHFFFAOYSA-N |
M.W : | 344.42 | Pubchem ID : | 60146215 |
Synonyms : |
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Chemical Name : | tert-Butyl 3-(2-(tosyloxy)ethoxy)propanoate |
Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P280-P301+P312-P302+P352-P305+P351+P338 | UN#: | |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
55% | With triethylamine; In tetrahydrofuran; at 0 - 20℃; for 16h; | To a solution of Compound (g-2) (0.20 g, 1.1 mmol) and triethylamine (0.31 g, 3.2 mmol) in THF (15 mL) was added p-toluenesulfonyl chloride (0.30 g, 1.6 mmol) at 0 C. over 10 minutes, and then the reaction mixture was stirred at at room temperature 16 hours. The solvent was removed in vacuo, and the residue was purified by preparative TLC (pentane:ethyl acetate=4:1) to give Compound (h-1) (0.20 g, 55% yield). (1098) 1H-NMR (CDCl3, 400 MHz) delta: 7.71 (d, J=8.2 Hz, 2H), 7.27 (d, J=8.2 Hz, 2H), 4.07-4.05 (m, 2H), 3.55-3.54 (m, 4H), 2.39-2.33 (m, 5H), 1.36 (s, 9H). |