成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 10157-76-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 10157-76-3
Chemical Structure| 10157-76-3
Structure of 10157-76-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 10157-76-3 ]

Related Doc. of [ 10157-76-3 ]

Alternatived Products of [ 10157-76-3 ]
Product Citations

Product Details of [ 10157-76-3 ]

CAS No. :10157-76-3 MDL No. :MFCD00041919
Formula : C19H32O3S Boiling Point : -
Linear Structure Formula :CH3C6H4SO3C12H25 InChI Key :QHKNLARMWXIVSM-UHFFFAOYSA-N
M.W : 340.52 Pubchem ID :82417
Synonyms :

Calculated chemistry of [ 10157-76-3 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 23
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.68
Num. rotatable bonds : 13
Num. H-bond acceptors : 3.0
Num. H-bond donors : 0.0
Molar Refractivity : 98.46
TPSA : 51.75 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : Yes
CYP2D6 inhibitor : No
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -3.39 cm/s

Lipophilicity

Log Po/w (iLOGP) : 4.63
Log Po/w (XLOGP3) : 7.03
Log Po/w (WLOGP) : 6.7
Log Po/w (MLOGP) : 4.73
Log Po/w (SILICOS-IT) : 5.42
Consensus Log Po/w : 5.7

Druglikeness

Lipinski : 1.0
Ghose : None
Veber : 1.0
Egan : 1.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -5.72
Solubility : 0.000656 mg/ml ; 0.00000193 mol/l
Class : Moderately soluble
Log S (Ali) : -7.93
Solubility : 0.00000397 mg/ml ; 0.0000000117 mol/l
Class : Poorly soluble
Log S (SILICOS-IT) : -7.26
Solubility : 0.0000188 mg/ml ; 0.0000000553 mol/l
Class : Poorly soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 2.0
Synthetic accessibility : 3.44

Safety of [ 10157-76-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 10157-76-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10157-76-3 ]

[ 10157-76-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10157-76-3 ]
  • [ 84851-56-9 ]
  • [ 119839-17-7 ]
YieldReaction ConditionsOperation in experiment
88.5% In N-methyl-acetamide; EXAMPLE 33 1.8 g (10 mmol) of (+)-methyl 4-(1-hydroxyethyl)benzoate (V-1) obtained in Example 1 was dissolved in 30 ml of dimethylformamide and then cooled to 10 C. 0.3 g (13 mmol) of sodium hydride was added thereto and stirred at a temperature of 30-35 C. for a hour. Then, 4.8 g (14 mmol) of n-dodecyl tosylate was added at a temperature of 20-25 C., and thereafter stirred at 40 C. for 3 hours. After completion of the reaction, the reaction mixture was poured into ice-water and then subjected to extraction-treatment with 100 ml of ether. The organic layer was water-washed and then concentrated in vacuo. The residue was then purified through a column chromatography to obtain 3.08 g of (+)-methyl 4-(1dodecyloxyethyl)benzoate (VII-33). Yield: 88.5%, nD20 =1.4762, [alpha]D20 +29.6 (c=1, CHCl3).
Recommend Products
Same Skeleton Products

Technical Information

Historical Records
; ;