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  I741    AKSci Bulk Reagent
(2S,4S)-2-(Dimethylaminocarbonyl)-4-mercapto-1-(4'-nitrobenzyloxycarbonyl)-1-pyrrolidine
, 98%
 
4-Nitrobenzyl (2S,4S)-2-(Dimethylcarbamoyl)-4-mercapto-1-pyrrolidinecarboxylate




IDENTITY
CAS Number:96034-64-9
MDL Number:MFCD08063348
MF:C15H19N3O5S
MW:353.39
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:119°C (246°F)
Optical Rotation:+8.5 ° - +10.5 ° (c=1% w/v in Chloroform)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 (2S,4S)-2-(Dimethylaminocarbonyl)-4-mercapto-1-(4'-nitrobenzyloxycarbonyl)-1-pyrrolidine is an advanced intermediate for the side chain used in the preparation of the carbopenem Meropenem.

REFERENCES
[1]Tewari, Neera; George, Vinod; Mane, Avinash Sheshrao; Meeran, Hashim Nizar Poovanathil Nagoor; Prasad, Mohan A process for the preparation of carbapenem compounds PCT Int. Appl. (2007), WO 2007029084 A2 20070315.
[2] Ageno, Takafumi; Okajima, Motonori; Koga, Teruyoshi Improved process for producing intermediate for side chain of carbapenem PCT Int. Appl. (2010), WO 2010073706 A1 20100701.
[3] Sureshkumar, Kanagaraj; Senthilkumar, Udayampalayam Palanisamy; Maruthi Chandrasekhara Kishor, Addanki; Vinod Babu, Dasari; John Bosco, John Peter; Karthikeyan, Lakshmi Narayanan An improved process for the preparation of carbapenem antibiotic PCT Int. Appl. (2010), WO 2010097686 A1 20100902.
[4] Karale, Sanjay Nivrutti; Jangale, Arvind Atamaram; Kaldate, Ram Dattatraya An improved process for the preparation of meropenem PCT Int. Appl. (2011), WO 2011141847 A1 20111117.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Notavailable


Current as of November 8, 2024


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All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Carbapenems


PubChem
  @PubMed
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