3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt, R 41468 (+)-tartrate salt
IDENTITY
CAS Number:
83846-83-7
MDL Number:
MFCD11864992
MF:
C26H28FN3O9
MW:
545.51
EINECS:
281-062-8
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:
>98% (HPLC)
Physical Form (at 20°C):
Solid
Melting Point:
163-168°C
Long-Term Storage:
Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
UN #:
UN2811
Hazard Class:
6.1; Poison
Packing Group:
III
A hazmat fee may apply to certain package sizes and shipment methods. Please check pricing table for an indicator of applicable hazmat fees.
BIOLOGICAL INFO
Application(s):
A selective serotonin agonist
REVIEW Ketanserin tartrate is a salt of Ketanserin. Ketanserin is reported to have a high affinity for multiple G protein-coupled receptors, such as serotonin receptors. Ketanserin is a selective SR-2/SR-1C antagonist. It has been used to distinguish between SR-1D and SR-1B subtypes. Additional studies have noted that Ketanserin is able to differentiate between recombinant human forms of these receptors with a higher affinity for SR-1Dalfa receptors compared to SR-1Dbeta receptors. Ketanserin tartrate is an inhibitor of SR-2A and SR-2C.
REFERENCES
[1]
Van Nueten, J.M., et al. 1981. J. Pharmacol. Exp. Ther. 218: 217-230. PMID: 6113280
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