GABAergic, cholinergic, and monoaminergic neuronal systems enhancer
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REVIEW A nootropic antidementia drug of the racetam family. Nefiracetam's cytoprotective actions are mediated by enhancement of GABAergic, cholinergic, and monoaminergic neuronal systems that give antiamnesia effects to the Alzheimer's type and cerebrovascular type of dementia.
REFERENCES
[1]
Vincent F, Nguyen MT, Emerling DE, Kelly MG, Duncton MA (2009). Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Bioorg Med Chem Lett. 19(23):6793-6. PMID 19850474.
[2]
Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Fukunaga K, Narahashi T (2009). Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons. Neuroscience. 160(2):484-91. PMID 19272425.
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