REVIEW Toltrazuril is a triazinone used to treat coccidiosis, an infection of intestinal epithelium caused by protozoan parasites of family Eimeriidae. All livestock species, as well as wild animals, can be infected. Toltrazuril has demonstrated powerful anticoccidial activity against multiple life cycle stages of various Eimeria spp. in birds and mammals.
Gallenkamp, Bernd; Guenther, Andreas; Mohrmann, Karl Heinrich; Schmidt, Thomas 1,3,5-Triazine-2,4,6(1H,3H,5H)-triones Ger. Offen. (1986), DE 3516632 A1 19861113.
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Lantzsch, Reinhard 1-Methyl-1,3,5-triazine-2,4,6(1H,3H,5H)-triones Ger. Offen. (1986), DE 3516631 A1 19861113.
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Wroblowsky, Heinz Juergen; Heinrich, Josef; Doering, Fritz Multi-step process for the preparation of toltrazuril Ger. Offen. (1994), DE 4239000 A1 19940526.
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